Sentences with phrase «developmental gene studies»

The soft body of D. cactiformis suggests that arthropods grew armour on their legs first, rather than their bodies, contradicting the results of some developmental gene studies.

Not exact matches

In February, the United Kingdom approved using the method on human embryos at the Francis Crick Institute in London, but only within a narrow capacity: Researchers can edit genes in non-viable human embryos for a limited period and only to study developmental biology related to in vitro fertilization.

The shared patterns of gene expression in the limbs and phallus are generated in part by a common set of noncoding DNA, also called «elements» or «enhancers,» which act to control gene expression in both of these structures, argues a study published October 1 in Developmental Cell.

Jiang said autism researchers worldwide could use the mouse model to study ways to compensate for the gene and improve symptoms in people with autism spectrum disorders and Phelan - McDermid Syndrome, a more profound developmental condition caused by mutations to SHANK3 and other genes in chromosome 22.

But a new study led by a University of Utah researcher and published in Developmental Psychology suggests that even though genes likely play a part, they may not be the whole story.

The study makes progress toward using gene editing to prevent genetic diseases, but there's still has a long way to go before clinical testing can begin, says Janet Rossant, a developmental biologist at the Hospital for Sick Children and the University of Toronto.

The study involved extracting Ribonucleic acid or RNA — found in the cells of all living organisms — to develop a transcriptome — the gene readouts in a cell — to examine what occurs during the different developmental stages of the cockroach pregnancy and to explore if those changes hold wider applications for other mammals.

The study of almost 8,000 families, published today (21 March) in Nature, found for the first time that mutations outside of genes can cause rare developmental disorders of the central nervous system.

«Only a limited number of studies have investigated the interplay between specific robust genes associated with the development of alcohol dependence and environments during the critical developmental period of adolescence,» said Bierut.

But this is the first time, to my knowledge, that the direct link is established from a novel gene to a novel structure to the invasion of a completely new ecological opportunity,» said Abderrahman Khila, an evolutionary and developmental genomicist at the Institute of Functional Genomics of Lyon, who led the study on the delicate insects called water striders.

The research team led by Prof. Dr. Ingrid Lohmann of the Centre for Organismal Studies (COS) studied the function of a special developmental gene of the Hox gene family.

«Information from this study could help lay the groundwork for therapies that address developmental missteps tied to Hox genes and their regulators.»

Ian Dworkin, a geneticist who studies fly evolution at McMaster University, noted that in the literature of evo - devo research — which looks at the role of developmental mechanisms in evolutionary changes — examples of co-opted genes are abundant.

Using the Drosophila melanogaster fruit fly as a model organism, the team led by Prof. Dr. Ingrid Lohmann at Heidelberg University's Centre for Organismal Studies was able to show how a special developmental gene from the Hox family influences germline stem cells.

This groundbreaking research allows researchers to directly study human development genes, says developmental biologist Dieter Egli of Columbia University.

Either way, previous studies have shown that proteins made from Jumonji genes work to control many other genes that orchestrate developmental processes — and that environmental stress, such as from heat, can change the way these genes turn on and off.

To find that gene, developmental biologist Deepak Srivastava of the University of Texas Southwestern Medical Center at Dallas and colleagues studied development of the mouse heart, in which a transcription factor called dHAND was known to turn on an array of crucial genes.

«The fungus lost a crucial energy - producing gene while the algae retained a full - length copy of this gene,» said Cloe Pogoda, lead author of the study and a graduate researcher in CU Boulder's Department of Molecular, Cellular and Developmental Biology.

The study team was able to diagnose children who had new mutations in genes already linked to developmental disorders - approximately one quarter of the patients in the study.

1) Co-authors of the gata5 study, published in Genes & Development, were lead author Jeremy Reiter, and Jonathan Alexander, both MD / PhD students funded by the NIH Medical Scientific Training Program and students in Stainier's lab, Deborah Yelon, PhD, a postdoctoral fellow in Stainier's lab, Adam Rodaway, PhD, and Roger Patient, PhD, both of Developmental Biology Research Centre, The Randall Institute, King's College London, and the late Nigel Holder, PhD, of the Department of Anatomy and Developmental Biology, University College London.

Henk Stunnenberg, leader of one of the research groups that carried out the study and coordinator of both Heroic and the recently started High Impact Project BLUEPRINT, said: «The epigenetic make - up - a layer of regulatory instructions on top of the genome - of the pure embryonic stem cells shows remarkable and unexpected features, in particular with respect to developmental genes.

The study zeros in on the genes that may lead to the marked extroverted behavior seen in children with Williams syndrome, demonstrating that «hyper - sociability» — especially the drive to greet and interact with strangers — follows a unique developmental path.

The study of almost 8,000 families, published in Nature, found for the first time that mutations outside of genes can cause rare developmental disorders of the central nervous system.

The finding is a landmark in the new field of evolutionary developmental biology, or «evo - devo,» as its proponents call it, in which scientists study the patterns of gene expression in embryos to peer backward in time.

A new study, led by Juha Kere (KI / SciLifeLab), has uncovered a link between a variant of the NCAN gene and developmental dyslexia.

Here we present 19 de novo mutations in this gene, including five missense mutations, identified by the Deciphering Developmental Disorder study.

The paucity of single nucleotide diversity among breeds is consistent with other studies (29 — 32) and stands in stark contrast to the abundance of coding repeat variation we found in these same genes known to be involved in the developmental processes under selection in the radiation in dog breed morphologies.

Genetic studies have indicated that genes often play an important role in the development of mental disorders, via developmental pathways interacting with environmental factors.

For instance, developmental studies of common dopamine (DA)- regulating gene polymorphisms and their interactions with environmental factors, both positive and negative, were recently examined in meta - analysis by Bakermans - Kranenburg and van Ijzendoorn (2011).