As a cat matures, there is a natural immunity that
develops against this parasite.
Not exact matches
H. contortus has become resistant to all major treatments
against parasitic worms, so its genome is a good model to understand how drug resistance
develops in this complex group of closely related
parasites and will also reveal further potential drug and vaccine targets.
This finding also paves the way for practical applications: the ETH spin - off Malcisbo, which came from the microbiologist's laboratory, endeavours, on the basis of these surface sugar structures to
develop novel vaccines
against parasites and pathogenic germs for livestock and humans.
Researchers at Stanford University purified the proteasome from the malaria
parasite and examined its activity
against hundreds of different peptide sequences using a novel method
developed at the University of California, San Francisco.
«Exploring this further opens up the possibility that we could use this knowledge
against the
parasite by
developing tools with crucial chemicals found in human odour.»
We've already moved away from using quinine to treat cases as the malaria
parasite has become more resistant to it, but if further drug resistance were to
develop against our most valuable malaria drug, artemisinin, we would be facing a grave situation.
This discovery will help to
develop crop plants that feature enhanced protection
against this type of
parasites.
Krogstad said that the same biotechnology that helped the team
develop the new drug has also identified similar drugs that also hold promise
against drug - resistant
parasites.
Medical researchers have
developed a new treatment
against drug - resistant strains of the Plasmodium falciparum
parasite that causes malaria.
A better approach, however, may be to
develop drugs
against the PfEMP1 gene - switching mechanism, which presumably varies little from
parasite to
parasite.
It would be the only vaccine yet
developed against a human
parasite, an achievement of Nobel caliber.
«A global disaster,» predicts another, contemplating what could happen if malaria
parasites worldwide
developed resistance
against the new artemisinin - based combination therapies (ACTs) that have become the gold standard.
«As drug resistance is a major problem for malaria control and eradication, it is critical that that we continue to
develop new antimalarials that act
against previously unexploited targets in the
parasite to keep priming the drug pipeline.»
Scientists have been working for decades to
develop a vaccine
against malaria, but the Plasmodium
parasite is a formidable foe.
Previous studies had shown that the apicoplast - targeting drugs have a delayed - death effect: They allow the
parasite to grow and replicate in the liver, where the immune system can
develop antibodies
against the invaders.
«But the differences discovered in the distribution machinery in
parasites and humans are of particular interest for
developing new medicines
against the sleeping sickness and other illnesses caused by trypanosomes in humans and animals.»
The findings could also help to
develop new medicines
against the diseases caused by the
parasites.
Their team has
developed an experimental vaccine
against Leishmania
parasites.
Developing a vaccine
against a
parasite that is notorious for hiding from the host immune response would take many years during which several bird species would likely become extinct.
Giving your dog SENTINEL ® Brand Products every 30 days prevents flea eggs from
developing into adults, breaking the life cycle, and prevents infestations while protecting your dog
against potentially deadly heartworms and a broad spectrum of intestinal
parasites.
Happily, given its significance in
developing countries, the paper, «Antibodies to PfSEA - 1 block
parasite egress from RBCs and protect
against malaria infection,» is not behind the Science subscription wall.