Sentences with phrase «develops over a number of years»

Kidney disease is one more potential complication of poorly controlled diabetes, and, unfortunately, it can develop over a number of years before symptoms show.

Recently introduced in Abu Dhabi public schools, the New School Model was developed over a number of years by local educators and consultants.

PAT online has been developed over a number of years in response to feedback from teachers.

Ballarat Heritage Homestay is a concept in accommodation that has been nurtured and developed over a number of years.

Not exact matches

While emerging market indexes have been on a wild ride over the past few years, she thinks a number of developing nations are on the cusp of great things.

Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.

Over the years, the iFranchise Group has developed a number of approaches to draw out meaningful answers.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Worse, over the past 12 years, these low numbers have barely budged, meaning that the vast majority of employees worldwide are failing to develop and contribute at work.

On the profits front, we've developed a number of approaches over the years to understand what drives cyclical fluctuations in profit margins (see for example Recognizing the Valuation Bubble in Equities and The Coming Retreat in Corporate Earnings).

Journalist Peter Seewald became famous for his books written in collaboration with Joseph Ratzinger, later Benedict XVI: what began as one interview for a major German newspaper developed into a series of books over a number of years, exploring deep theological issues and the complex debates of our time.

Nonetheless, the fear of mission board executives that growing numbers of enthusiastic but poorly prepared volunteers would undo some of the self - sufficiency that had been developed in national churches over the years is not completely unfounded.

Boston Showcase has developed a number of long - term relationships over the years, but that does not mean maintaining its clientele has always been easy.

Over the past 10 years, Chef Segarra has developed a broad range of skills and experience working with top chefs in a number of acclaimed and Michelin - starred restaurants across the country.

We've developed these processes over a number of years because we recognise the need for brands to consider their packaging design and explore plastic - free alternatives.

Over the years I've collected and developed a number of recipes for pasta sauces that don't need cooking yet are still hot with chile heat and keep me out of the kitchen.

As American consumers gain interest in Scottish artisanal products, Atalanta's product team and Scottish Dairy have been working for over a year to develop strong relationships with a number of individual producers in order to find the right products for the marketplace.

Over the last 20 years, he and the Circle team have developed a number of qualities that set Circle apart from other agencies.

«As these drugs are considerably cheaper than current therapies, they can improve treatment in the developing world where the number of deaths from cancer is predicted to increase significantly over the next ten years,» said Dr Federica Sotgia, another leader of the study.

A number of theories have been developed over the years to explain more recent extinctions such as those at the end of the last ice age, including human hunting, climate change, disease, and even a cosmic impact such as an asteroid or comet.

This year, forecasters with the National Oceanic and Atmospheric Administration are expecting to see above - average storm numbers in the Atlantic, despite the uncertainty of whether an El Niño will develop over the summer.

Because there have already been a number of good articles on Next Wave over the last few years that will help you develop the proper networking message, I won?t duplicate that information here.

By tuning the model to replicate population data, such as the number of people at risk for developing TB and the fraction of TB patients who have drug resistance, the model can predict changes in the TB disease burden — or number of cases — over many years.

TESS relies upon a number of innovations developed by the MIT team over the past seven years.

The number of people in Bangladesh dying from chronic diseases such as cancer, diabetes and hypertension — long considered diseases of the wealthy because the poor didn't tend to live long enough to develop them — increased dramatically among the nation's poorest households over a 24 - year period, suggests new research from the Johns Hopkins Bloomberg School of Public Health

Over the years, I have developed and combined a number of strategies that have helped my keep my training on track despite having a very busy schedule.

In the meanwhile, a big number of studies have shown that consuming a moderate amount of full - fat diary products instead their low - fat versions can reduce the risk of developing heart disease and diabetes, while in healthy people over 60 years of age, a higher cholesterol has been associated with a lower risk of mortality.

Over the years I have developed a number of survival strategies that I want to share with you.

Lucie developed her knowledge and skills in the fitness industry over a number of years alongside working in the science sector and holds three medical science degrees, a Bachelors (BSc), a Masters (MSc) and a Doctorate (PhD).

Over the past year, I've developed a number of presentations focused on wellness.

A fair number of boomers have done some personal growth work over the years and have developed useful interpersonal skills.

I have met a number of guys over the years on match.com that I developed activity partner relationships with.

Sheen's next major success was also a comedy, the 1991 military - film satire Hot Shots, and while box - office blockbusters tended to elude him, Sheen worked steadily over the next several years, and racked up a respectable number of box - office successes.By this time, Sheen had developed a reputation as a hard - living star who spoke his mind regardless of the consequences, but his fun - loving image began to take on a darker hue in the mid -»90s.

The article says that over the next several years the nea will spend $ 600,000 and involve the faculties of 29 elementary, middle, and high schools in an effort to review literature, identify objectives, and eventually develop curricula and programs in a number of subject areas.

A few agreed to reduce the number of not - yet - proficient students by 50 percent over the next six years, but most developed their own twist on «annual measurable objectives.»

Learning progressions, typically extending over a number of years of learning, describe typical sequences and paths of learning and make explicit what it means to develop deeper understandings and more advanced skills in an area of learning.

Over the last 5 years, the school has increased the number of community programmes offered and developed relationships with a range of clubs and organisations, seeing their community income grow from # 24,800 in 2006/7 to # 82,200 in 2011/12.

The intervention was developed and trialled in New Zealand over 20 years ago and is now implemented in a number of education systems.

Over the next ten years, she worked on a number of programs for KDE, culminating with the Kentucky Instructional Discipline and Support (K.I.D.S) project, a statewide initiative to help schools and districts develop positive, proactive, and instructional discipline policies.

Well that's what has been happening, as new exams have been developed and are being phased in over a number of years.

Over the last number of years, a number of initiatives have been piloted with a view to identifying how a structured information process might be developed e.g. meetings with parents who are enrolling their children in primary or post primary schools, or parents who are seeking the establishment of a special class or home tuition for their children.

«Only a select number of drivers have driven the Lotus circuit over the years, but now anyone can get a closer look at where some of the most iconic British sports and racing cars have been tested and developed.»

From their website: «Over the years, Impelsys has developed successful ebook strategies for a number of leading publishers worldwide.

The number of listed companies in Asian emerging markets has grown by 206 % over the last 20 years versus 36 % in developed countries.1 Investors who seek exposure to the growing number of listed companies in Asia can do so by investing in this Fund.

Over twenty years later, the number of dogs presenting with this disease prompted the Swedish Kennel Club to become one of the first to develop a program to reduce the incidence of hip dysplasia.

There are a number of nifty ideas I've developed over the years to allow aggressive dogs good veterinary care.

The most critical of the 20 policies that we have developed over the past 10 years of being in the trenches of animal rescue and welfare is number one.

If you don't even know how number of total employees has grown and developed over the last three years, you can not do that math.

The Ministry of Culture noted that the online games industry has been developing rapidly over the past few years but that the regulations put into place have not been clear and this has led to a number of online game operators not following the rules that were put in place to protect a user's rights.

Having developed a number of titles over the years for their various platforms, it's become increasingly apparent that unless you are published by Nintendo you don't tend to do very well.