Sentences with word «dexmedetomidine»

Listen to a short podcast and learn more about Canine Noise Aversion in shelters and how SILEO ® (dexmedetomidine oromucosal gel) can be used for treatment.

Mice were anesthetized with intramuscular injections of dexmedetomidine hydrochloride (0.4 mg / kg; Pfizer), followed by ketamine hydrochloride (40 mg / kg; Bioniche Pharma).

Dexdomitor ® (dexmedetomidine hydrochloride)- A sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.

After completion of the pilot study, the research team hopes to publish the results with the eventual goal of pursuing a larger, randomized controlled study that can provide the kind of data needed to support the use of PCA with dexmedetomidine in a clinical setting.

In the US, most cats that undergo surgery are given the sedative drug dexmedetomidine (DXM) to calm them down prior to general anesthesia, which puts them to sleep.

In Dr. Chlan's study, ICU patients gave themselves pre-measured doses of dexmedetomidine via a monitored IV - fusion pump if they started to feel anxious.

Supported by a grant from Ohio State's Center for Clinical and Translational Science, the research team has just embarked on similar pilot study with burn patients self - administering dexmedetomidine during dressing changes.

In an effort to stop that cycle, the research team turned to the results of an earlier study conducted by Dr. Chlan which allowed critically ill patients on mechanical ventilation to self - administer a sedative called dexmedetomidine.

Sileo, aka dexmedetomidine, has a low risk of complications, but those complications are serious.

Some supplements containing amino acids, such as L - theanine or alpha - casozepine, can be useful, said Landsberg, adding that he also may use selective serotonin reuptake inhibitors like fluoxetine, clomipramine or the recently licensed dexmedetomidine, an oral mucosal gel licensed for as - needed use before a fear - or anxiety - inducing event, or trazodone or benzodiazepine.

Although dexmedetomidine (the active ingredient in SILEO) can not be absorbed through intact skin, it can be absorbed through breaks in the skin and through mucous membranes.

Dog owners now have a new treatment option with SILEO ® (dexmedetomidine oromucosal gel), the first and only medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of noise aversion in dogs.

Although the active ingredient in SILEO, dexmedetomidine hydrochloride, is approved for use as a sedative for humans, it has not been evaluated in pregnant women.

This presentation considers the pharmacology, clinical presentation and nuanced usage of several injectable anesthesia regimes utilizing the drug dexmedetomidine.

SILEO is an oromucosal gel formulation of dexmedetomidine, a highly selective alpha - 2 adrenoceptor agonist that blocks norepinephrine.

For moderate to severe pain, stronger medications, such as injectable or continuous rate infusion of pure opioid (e.g., fentanyl, hydromorphone) + / - other medications (e.g., dexmedetomidine, ketamine, lidocaine) should be considered.

FLORHAM PARK, N.J., June 19, 2014 — Zoetis Inc. today announced a lower concentration of DEXDOMITOR ® (dexmedetomidine), a sedative and preanesthetic.

SILEO ® (dexmedetomidine oromucosal gel) is the first and only FDA - approved medication indicated for the treatment of canine noise aversion.

SILEO (dexmedetomidine oromucosal gel): This is a new oromucosal gel formulation.

Do not use SILEO in dogs with severe cardiovascular disease, respiratory, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue or in dogs hypersensitive to dexmedetomidine or to any of the excipients.

Veterinarians will often administer small doses of an antidote to DXM to counterbalance the bradycardia and raise the heart rate, but Dr. Manuel - Martin Flores and his colleagues at the Cornell University Hospital for Animals observed that cats subjected to the stresses of these dexmedetomidine - antidote treatments did not do well and often developed dangerously low blood pressure.

SILEO ® (dexmedetomidine oromucosal gel) is a new treatment for canine noise aversion, and the first and only one to be approved by the FDA.

Important Safety Information: Do not use SILEO in dogs with severe cardiovascular disease, respiratory, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue or in dogs hypersensitive to dexmedetomidine or to any of the excipients.

Some versions of human medications have received approval by the Food and Drug Administration for specific mental - health uses in pets, including the antidepressant clomipramine (Clomicalm) for separation anxiety in dogs, the sedative dexmedetomidine (Sileo) for dogs with noise - aversion problems, and selegiline (Anipryl), a drug often used to treat Parkinson's disease in humans, for canine cognitive dysfunction.

FLORHAM PARK, N.J. — May 16, 2016 — Dogs that experience fear and anxiety in response to loud noise such as fireworks, thunder, and construction work now have a new treatment option with the launch of SILEO ® (dexmedetomidine oromucosal gel), the first and only medication approved by the U.S. Food and Drug Administration (FDA) for treatment of noise aversion in dogs.

The efficacy and safety of SILEO ® (dexmedetomidine oromucosal gel) have been proven in several placebo - controlled studies.

The primary active ingredient is dexmedetomidine hydrochloride.

Dexmedesed ® (dexmedetomidine hydrochloride) Federal law restricts this drug to use by or on the order of a licensed veterinarian.