Sentences with phrase «diabetic mouse models»
In fact, the speed and kinetics of touching down to safe blood glucose levels are identical in diabetic mouse models treated with Ins - PBA - F and in healthy mice whose blood sugar is regulated by their own insulin.
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«By decreasing ROS levels within a chronic wound in a diabetic mouse model, my lab was able to normalize conditions and heal the wound,» Martins - Green said.
«Novel «smart» insulin automatically adjusts blood sugar in diabetic mouse model.»
«This is the first study conducted on the diabetic mouse model that supports the LYP gain - of - function hypothesis,» says Dr. Kissler.
Not exact matches
One of the most popular models is the immunodeficient nonobese diabetic severe combined immunodeficiency (NOD scid) gamma (NSG) transgenic mouse line, which can be endowed with a humanized immune system using CD34 + hematopoietic stem cells.
The group also tested low - dose topical application of growth factors on diabetic mice, which are a common model for impaired wound healing.
To rule out that the induction observed was due to other diabetic - associated alterations in the pancreas, we performed a control experiment in which we injected Tg - hIAPP mice with pancreas homogenate from a diabetic model not associated with IAPP aggregation.
The results demonstrated that this new molecule was safe and effective, causing significant improvement in mouse models of both acute uveitis and chronic diabetic inflammation, with no apparent side - effects.
Because PD - L1 / programmed cell death (PD - 1) deficiency accelerates development of diabetes in mouse models, Nasr et al. hypothesized that a defect in the PD - L1 / PD - 1 pathway may underpin the hyperglycemia observed in the nonobese diabetic (NOD) mouse model.
«Our plan is to apply such materials to diabetic wounds in mouse models in order to evaluate their efficacy.
Models of obesity - induced type 2 diabetes include the KK mouse and the Zucker diabetic fatty (ZDF) ratANCHOR ANCHOR.
The nonobese diabetic (NOD) mouse is a common model used for studying treatments for diabetes.
The Joslin researchers then transplanted these modified human diabetic cells into wounds in mice models of diabetes that also had suppressed immune systems so that they didn't reject human cells.