The initial application to
diabetic retinopathy shows proof - of - principle in a very important disease, but the approach can be adapted to other powerful drugs and diseases where localized activity is needed.»
Not exact matches
According to the World Health Organization (WHO),
diabetic retinopathy is the leading cause of blindness in adults of working age, and its incidence is
showing an upward trend.
«Our results
show that normalized blood glucose levels alone are not sufficient to fully treat
diabetic retinopathy,» said Dr. Alice Ly (PROT), lead author of the study.
Previous studies have
shown a link between OSA and
diabetic retinopathy.
The results
showed that
diabetic retinopathy prevalence was higher in patients with OSA (42.9 %) compared to those without OSA (24.1 %).
Meanwhile, the study also
showed that patients who received treatment for OSA using a machine connected to a face mask that delivers pressure to prevent the blockage of the airways during sleep had a lower risk of developing advanced
diabetic retinopathy compared to patients who did not receive the treatment.
Harris et al. [2] also provided evidence of the presence of retinal hypoxia in the early stages of diabetes by
showing that contrast sensitivity was improved when patients with early
diabetic retinopathy were made hyperoxic.
Development of this drug was based on earlier work by Dr. Feener's lab, which
showed that activation of PKal can induce retinal edema in experimental models of
diabetic retinopathy.
Dr. Rotimi's lab has
shown that a polymorphism in the endothelial nitric oxide gene is associated with
diabetic retinopathy in Africans.
A new study published in the journal Science Translational Medicine reveals new steps in the development of
diabetic retinopathy and
shows that they can be prevented using targeted drugs.
Dr. Kempner was the first to
show the world that a diet composed entirely of extremely low fat foods — rice and fruit — could not only reverse type 2 diabetes, but also reverse hypertension, kidney disease and
diabetic retinopathy, provided that the amount of fat in the diet was kept extremely low (5).