Sentences with phrase «diagnostic assays»
"Diagnostic assays" refers to tests or examinations conducted to identify or analyze a specific condition, illness, or disease in a person or a sample. These tests help healthcare professionals determine the presence, extent, or characteristics of the health issue, aiding in correct diagnosis and appropriate treatment. Full definition
Their pilot studies provide the basis for diagnostic assays for...
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It will be extremely important to identify and characterize those viruses as quickly as possible — to get a head start on the development of diagnostic assays for surveillance and drugs, or vaccines for treatment — before they have a chance to really spread.»
Identification of Borrelia burgdorferi ospC genotypes in canine tissue following tick infestation: implications for Lyme disease vaccine and diagnostic assay design.
Within our lab we exploit the unique DNA methylation profiles of brain cells to create molecular diagnostic assays capable of detecting peripheral neurological cell free DNA.
Esko is collaborating with Zacharon Pharmaceuticals, a San Diego - based biotechnology company, to develop a commercial diagnostic assay for differentiating forms of MPS from urine and blood samples, a screening test for newborns and a tool for measuring the biochemical response of MPS patients to existing and novel therapies.
Since we are developing a technology that makes the current and long - standing internationally accepted standards for disease screening in developing countries more portable — rather than creating an entirely new diagnostic assay — we anticipate that a relatively fast time to adoption by clinicians and health workers may be possible.
Wondji says: «For the first time, we have been able to identify a molecular marker for metabolic resistance (the type of resistance most likely to lead to control failure) in a mosquito population and to design a DNA - based diagnostic assay.
This proof - of - principle work hints at the possibility of doing away with computers to read diagnostic assays in the future, says Milan Stojanovic of Columbia University.
«By requiring both a documentable fever and a positive diagnostic assay result for Ebola infection before initiating treatment in these animals, we were able to use MB - 003 as a true therapeutic countermeasure,» said senior author Gene Olinger, Ph.D., of USAMRIID.
So we wanted to elucidate the molecular basis of that resistance in the population and design a field applicable diagnostic assay for its monitoring.»
NIAID's Bradley Groveman, foreground, and Christina Orru using the RT - QuIC diagnostic assay, which they helped adapt to detect Parkinson's disease and dementia with Lewy bodies.
«For field use, where you don't have very much refrigeration — in the developing world, for example — you could have an infinitely stable diagnostic assay for infectious disease.»
The need for diagnostic devices for biodefense is not going away, Singh said, since there are always new diseases springing up that lack good diagnostic assays.
The study compared four PD - L1 IHC diagnostic assays developed in conjunction with four PD - 1 / PD - L1 immune checkpoint inhibitors, which are used in NSCLC clinical trials.
Thus, translating research grade NGS to a clinical cancer diagnostic assay requires extensive optimization and investment.
Genetic testing panels — focused diagnostic assays that interrogate a specific set of genes associated with a certain phenotype or disorder — have been a routine part of clinical care for decades.
Prior to Joining MHRP, Dr. Manak was the Chief Scientist of SeraCare Life Sciences Inc., where he led the development of seroconversion and performance panels widely used by the in vitro diagnostics community for development, evaluation and validation of in vitro diagnostic assays used in screening and monitoring of infectious diseases.
We continue to refine our understanding of the different stages of the infection and how this relates to the results of available diagnostic assays.
Represented Becton, Dickinson and Company in a patent infringement suit brought by Gen - Probe involving methods of automating nucleic acid diagnostic assays and related consumable products.
Identification of Borrelia burgdorferi OspC genotypes in canine tissue following tick infestation: implications for Lyme disease vaccine and diagnostic assay design.
Invivoscribe's collaboration with Thermo Fisher is a core part of its global initiative to develop and provide standardized molecular diagnostic assays to support precision medicine in the oncology field.
Testing can be completed within a timeframe similar to that of recent commercial diagnostic assays (less than 24 hours to determine repeat size and / or methylation status, less than 24 hours to determine the interruption status and percent methylation) and are comparable in terms of hands - on time required.
A potential problem is that vaccinated cats will also test positive on the routine tests used to detect FIV - infected cats, but newer diagnostic assays are becoming available that may overcome this problem.
Dr. Manak has helped set up and direct various collaborative programs with developers of infectious disease tests including Hologic, Roche, Bio-Rad, SpotOn and SeraCare as well as partnerships with government agencies for evaluation of diagnostic assays and devices.
Diagnostic assays for on - farm use have different constraints compared with those used in traditional laboratory environment
The scientists next plan to evaluate the precise roles of the five genes and to validate the accuracy of their diagnostic assay in a prospective clinical study.
The Institute hopes to eventually obtain viral isolates for medical countermeasure development and receive data on the performance of the diagnostic assays.
«We're looking at diagnostic assays for Ebola and Marburg viruses that we can actually take out into the field in Africa — dreadfully resource - poor environments, incredibly hot and where we need diagnostic assays,» Hayhurst says, referring to the Southwest Foundation's intentions for this technology.
Use of genomics to design a diagnostic assay to discriminate between Streptococcus pneumoniae and Streptococcus pseudopneumoniae — Matthew A. Croxen — Microbial Genomics
«Eight men and women associated with the Biotech Center have discovered drugs and diagnostic assays that are in human use today — and more innovations lie ahead.»
Key functions of the Core are to collect, process and store well - characterized biospecimens, access the comprehensive Biorepository for the development and validation of screening and diagnostic assays, and enable virological and immunological studies.
Currently research interests revolve around transfusion - transmitted viruses, blood screening and diagnostics assays, and transfusion efficacy.
SEngine Precision Medicine, instead, is pursuing an innovative approach for the development of novel targets and drugs for cancer therapy by using primary patient organoids initially derived for our diagnostic assay.
Dr. Mark Manak heads up the research activities of MHRP's Department of Laboratory Diagnostics and Monitoring, focusing on evaluation of diagnostic assays and their applications in screening for HIV and related infectious diseases and monitoring efficacy of intervention programs.
Executed and documented experimental test designs for donor screening and diagnostic assays, feasibility of a new donor screening system
Accomplished and highly motivated research professional with extensive experience in infectious disease (hepatitis C virus (HCV), Respiratory syncytial virus (RSV), dengue viruses, Herpes virus (HSV) and influenza viruses) in vaccine development, assay design, development and validation / verification molecular diagnostic assay (MGB - Pleiades chemistry).