Sentences with phrase «diagnostic biomarkers in»
DNA methylation profiles of the brain - derived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression
https://www.cambridge.org/ Not exact matches
Related Articles: Merck's Keytruda held back by docs who don't want to wait for diagnostics Bristol's Opdivo - Yervoy combo ups response rates in first - line lung cancer patients Roche's Tecentriq bursts onto immuno - oncology scene, with Merck and BMS in its sights Bristol - Myers» new Opdivo ad touts biomarker advantage over Merck's Keytruda Merck's Keytruda lines up its survival data for stepped - up battle with BMS» Opdivo
ProAxsis is a diagnostics company based in Northern Ireland, developing a range of products to identify active protease biomarkers of diseases.
The members of the initiative hope to improve early detection of cancer by making an impact in a variety of areas, including doing epidemiologic studies on risk factors, developing new and improved methods of diagnostic imaging, discovering and verifying new biomarkers as indicators of cancer, and developing new technologies to aid early detection.
«Researchers isolate novel urinary biomarkers that may indicate adrenal cancer: A quartet of metabolites found in urine samples may help solve diagnostic and treatment dilemmas associated with clinically silent adrenal masses.»
The combination of longitudinal biomarkers improves diagnostic accuracy compared with use of a single marker and provides a powerful tool in personalized medicine.
The information potential held by miRNAs, combined with the fact that they are stable in serum and plasma, has led to a rapidly growing interest in using miRNAs in blood as diagnostic and prognostic biomarkers.
His research focuses predominantly on oncology molecular diagnostics, particularly the source and utility of miRNA biomarkers in blood, and the development of innovative molecular diagnostics for the identification of mutations that can guide therapeutic decision - making.
«Our group, which includes more than 180 myeloma researchers worldwide, has updated the definition of multiple myeloma for diagnostic purposes to include validated biomarkers in addition to the current clinical symptoms used for diagnosis which include, elevated blood calcium levels, kidney failure, anemia and bone lesions,» said lead author S. Vincent Rajkumar, M.D. a hematologist at Mayo Clinic.
«Using biomarkers for cancer detection is an important advance in managing women with dense breasts and navigating many diagnostic challenges.
However, single biomarkers are biologically implausible as a diagnostic test for complex diseases like CFS and are likely to perform poorly in larger populations.
The identification of diagnostic tests or biomarkers that predict progression to active TB disease would greatly enhance TB control efforts in the United States and globally and allow physicians and public health officials to focus efforts on treatment of latent TB infection of those at greatest risk of progression to active, transmissible and potentially fatal disease.
«Lastly, the technique we have pioneered will likely be a valuable tool for scientists and clinicians studying the biology of complex nanoparticle populations,» Dr. Zhang said, «and may aid in the development of diagnostic tests using them as biomarkers.»
Our faculty pursues research in DNA analysis, GIS, disease diagnostics and other biomarkers, ecological anthropology, forensic anthropology, fossil excavation, modern Mayan cultures, Global and One Health, and both historic and prehistoric archaeology.
The Policies and Guidelines, ratified by IRDiRC members for implementation in their respective rare disease research programs, are structured around 11 major topics: data sharing and standards, ontologies, diagnostics, biomarkers, patient registries, biobanks, natural histories, therapeutics, model systems, publication and intellectual property, and communications.
A recent study reported that two oxysterol species, 15HC and 15KC, were increased more than three-fold in the blood of multiple sclerosis patients, suggesting a potential use for these oxysterols as diagnostic biomarkers.
And we are now taking advantage of the different skills that we have in the consortium to try to interpret these and see how they evaluate the potential to be a biomarker of either progression or an early diagnostic tool.
«Having been a partner with Roche for several years, we have every confidence that the combination of our own expertise and Roche's considerable capabilities in clinical development, biomarkers and diagnostics will help us maximize the potential for this programme,» commented Stuart W. Peltz, Ph.D., President and CEO of PTC.
According to a release from Dr. Hassan Dihazi, editor in chief, the journal covers all areas of proteomics including basic proteomic research; structural, functional, property, and interaction analysis of cellular systems, organelles, and protein complexes; and protein expression profiling for the discovery and validation of diagnostic and prognostic disease biomarkers.
RBM's initial molecular diagnostic test, VeriPsychTM, is a blood - based test that aids in the confirmation of diagnosis of recent - onset schizophrenia by evaluating a proprietary set of 51 biomarkers.
Our LabPMM labs in the USA, Europe, and Asia offer an ever - expanding menu focused on biomarkers that have demonstrated clinical utility to support patient stratification & enrollment in clinical trials, companion diagnostic development, and optimized treatment for patients.
Harshini Mukundan, of Los Alamos» Nuclear and Radiochemistry group made critical breakthroughs in optical detection techniques of diseases such as tuberculosis, allowing rapid detection in the field, and discovered an entirely new class of diagnostic molecules that led to chemical recognition of various biomarkers.
ACD technology is used in proprietary diagnostic tests for cancer management and to validate biomarkers for targeted therapeutic development.
SAN DIEGO, March 28, 2017 (GLOBE NEWSWIRE)-- Invivoscribe ® Technologies Inc., a global company with decades of experience providing internationally standardized clonality and biomarker testing solutions for the fields of oncology, personalized molecular diagnostics ®, and personalized molecular medicine ®, reports that its next - generation sequencing (NGS) LymphoTrack ® Assay kits are being used by its LabPMM ® clinical laboratories, pharmaceutical partners, and cancer centers to identify and monitor chimeric antigen receptor T - cells (CAR - T) and engineered T - cell receptors in peripheral blood of subjects in support of immuno - therapeutic drug development and treatment regimen development for both hematologic and solid tumors.
View the video and see where Olink Proteomics is today (at the forefront of targeted protein biomarker discovery), and where we see our future, in the development of precision diagnostics and the realization of precision medicine.
Biomarkers included are available to order as individual tests, or as a comprehensive profile to help provide simultaneous diagnostic information about multiple conditions in a single blood draw.
If cancer is actually suspected there is also a Biomarker screen that can aid in a diagnostic workup and therapeutic monitoring.