Sentences with phrase «diagnostic marker of»

Within diabetic populations, hyperglycaemia is considered the hallmark diagnostic marker of metabolic abnormality and a major contributor to T2DM associated macro - and micro - vascular complications.61 One study by Ash et al 36 saw 51 overweight / obese male subjects with T2DM assigned to one of three groups; (i) IER (four days 50 % ER, three days ad libitum intake / week), (ii) CER (30 % ER / day, all meals provided) and (iii) CER (30 % ER / day, food self - selected by the participant).

There are some signs that we are seeing through research that can be used as more early diagnostic markers of autism.

While we still do not know just how Alzheimer's progresses or what role the fibrils play, they are always found in Alzheimer's - ridden brains and are considered diagnostic markers of the disease.

Not exact matches

At one extreme, some certifiers have abandoned using SIDS as a cause - of - death explanation.7 At the other extreme, some certifiers will not classify a death as suffocation in the absence of a pathologic marker of asphyxia at autopsy (ie, pathologic findings diagnostic of oronasal occlusion or chest compression8), even with strong evidence from the scene investigation that suggests a probable accidental suffocation.

Mayo Clinic researchers have discovered a series of proteins that could be diagnostic markers to identify bipolar I disorder.

The company wanted to use it as a diagnostic marker for disease: If synthetic versions of antibodies could be tagged with aequorin in the lab, then whenever they matched up with an antigen (or surface protein) of a specific pathogen in blood or tissue, the sample would glow.

The goal is to identify new disease diagnostic markers and develop new therapies, according to the company's head of R&D in China, Andreas Tschirky, and chief scientific officer Li Chen.

Results again found a strong correlation between the presence of these epigenetic markers and AD, implying they may also provide a compelling diagnostic tool.

A detailed understanding of how TSPO binds to such markers opens up novel paths for diagnostic imaging and could constitute an important step along the way to early detection of such diseases and inflammations.

«We now also have a much better understanding of how TSPO recognizes and binds to diagnostic markers and drugs,» explains Markus Zweckstetter, head of research groups at the German Center for Neurodegenerative Diseases (DZNE), at the Max Planck Institute for Biophysical Chemistry, and at the Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB) at the University Medical Center of Göttingen (UMG).

The combination of longitudinal biomarkers improves diagnostic accuracy compared with use of a single marker and provides a powerful tool in personalized medicine.

«Our research translates this technological development over to the biosciences and offers the possibility of a new biomedical diagnostics technique capable of detecting the presence of even a single cancer marker molecule.»

Discovery improves understanding of the cause of allergic asthma and may serve as an early diagnostic marker.

But they provide additional gene markers in bipolar disorder that could potentially lead to the future development of diagnostics or treatments.»

Monitoring the levels of GARP on B cells may provide a very useful diagnostic marker for autoimmune disease.

Next steps involve further refinement of the process and identification of diagnostic risk markers for females.

For the first time, researchers report identifying a biological marker: the over-production of specific genes that could be a diagnostic indicator of mental illness in female psychiatric patients.

A type of antifungal antibody, called ASCA, is widely used as a diagnostic marker since it is highly elevated in the blood of patients with several chronic diseases including Crohn's.

A positive MST screen status turned out to be a marker for homelessness in the absence of further diagnostic information.»

At present, the most common, sporadic form of Alzheimer's disease is difficult to diagnose until symptoms are readily apparent and significant damage to the brain has occurred; findings from this study may provide clues to suitable diagnostic markers.

Also in patients where tissue diagnosis can not be obtained in spite of multiple biopsies, measurement of markers in bile fluid to improve our diagnostic ability would be of immense interest,» explained Dr. Navaneethan.

Gata5 a potential diagnostic marker for congenital heart disease The finding also suggests that gata5 could be a potential new diagnostic marker for congenital heart defects, as the researchers demonstrated that gata5 regulates the expression of a gene known as nkx2.5 which, when mutated in humans, causes human congenital heart defects and disease.

Floryne Buishand, 30, from the Netherlands, is a postdoctoral researcher at the National Cancer Institute / NIH, Bethesda, USA, studies genomic changes associated with endocrine cancers with the ultimate goal of identifying novel diagnostic and prognostic markers, as well as novel therapeutic targets.

The journal covers all aspects of surgical pathology, including classic diagnostic pathology, prognosis - related diagnosis (tumor stages, prognosis markers, such as MIB - percentage, hormone receptors, etc.), and therapy - related findings.

deCODE is continuing its research on both phenotypes to identify and analyze the roles of these genes, with the aim of finding novel diagnostic markers as well as drug targets that can be used to combat asthma and allergies by going to the underlying causes of both conditions.

The lack of specific markers of disease and the fact that the CFS diagnosis is controversial imply that the level of diagnostic accuracy and adherence to international criteria are likely to be variable.

Finally, we ask whether the mechanical differences between normal and cancer cells can be used as diagnostic or prognostic markers of cancer progression.

Examples include the study of allelic variation in the human genome and the development of computational methods for the discovery of cancer - associated genes and diagnostic cancer markers using genomic profiles derived from different tumor types.

Conversely, within non-diabetic populations, periods of IER (75 - 85 % ER on restricted days) do not typically affect fasting glucose levels 37, 41, 45, 48 or HbA1c 41, 48; results of which can often be replicated by short term CER studies.62 - 65These findings are unsurprising given that frank hyperglycaemia within the T2DM diagnostic range is effectively a late - stage manifestation of IR, which along with compensatory increases insulin secretion, can precede the onset of T2DM by many years.66, 67 Findings from one large scale prospective cohort study, Whitehall II, reveal a sharp increase in the trajectory towards fasting hyperglycaemia which is only detectable three years prior to diagnosis with T2DM.67 Consequently, it can be argued that changes in circulating insulin concentrations, fasting (hepatic) insulin sensitivity and glucose uptake / clearance are more sensitive markers of deteriorating glucose control than fasting glycaemia in non - diabetics.68 - 70

pH Alkalizer PM PROTM is specifically formulated with pH 7.5 TM to help maintain healthy pH levels; FruiteX - B ® Calcium Fructoborate helps to support healthy levels of C - Reactive Proteins (CRP), a diagnostic marker associated with inflammatory conditions; and SpectraTM Total ORACFN which may help to target the five major types of free radicals that studies suggest may be associated with unhealthy aging and chronic conditions.

pH Alkalizer PMTM is specifically formulated with pH 7.5 TM to help maintain healthy pH levels; FruiteX - BR Calcium Fructoborate helps to support minimum healthy levels of C - Reactive Proteins (CRP), a diagnostic marker associated with inflammatory conditions; and SpectraTM; Total ORACFN which may help to target the five major types of free radicals that studies suggest may be associated with unhealthy aging and chronic conditions.

Found in legumes, fruits, vegetables, herbs and wine, recent published human clinical research has demonstrated the ability of FruiteX - BTM to modulate key markers of inflammation and improve elevated serum levels of CRP, a diagnostic marker associated with inflammatory conditions.

It is considered the only diagnostic test for hypothyroidism and the most sensitive marker of peripheral tissue availability of thyroid hormones.

TRIB also acquired Fiomi Diagnostics, a Swedish company at an advanced stage in developing a panel of point - of - care cardiac marker assays, particularly for Troponin I. $ 60 mio «s already been spent on the technology, and it offers TRIB a slice of the $ 900 mio Cardiac POC diagnostics market, which is growing 14 % pa.

As markers flanking and successively closer to the disease gene are identified, the accuracy of a diagnostic linkage test is improved, but even relatively distant markers give some predictive information.

Various types of linkage tests have been most successful for identifying genetic markers located close enough to disease genes to be useful in diagnostic tests.

The three puzzle pieces (the three diagnostic indicators of attachment - based «parental alienation») are just easily identifiable definitive markers for cats in the garden.