Among formula fed infants, the PAF for
diarrhoeal disease associated with not sterilising with chemicals / steam was 12 %.
Population attributable fractions (PAFs) for
diarrhoeal disease associated with infant feeding variables were estimated as (proportion of cases exposed) × (OR − 1) / OR.13 Survival analysis was used to estimate the prevalence of breast feeding at age 6 months while allowing for censoring, due to some infants being aged under 6 months.
1.35 million people in developing countries, most of them children, die every year from
diarrhoeal diseases associated with lack of access to safe drinking water, inadequate sanitation, poor hygiene and overcrowding.
Not exact matches
Months since breast feeding cessation and duration of breast feeding were both significantly
associated with
diarrhoeal disease, but much of these effects were due to the inclusion of the currently breast fed and never breast fed infants; neither was statistically significant when these infants were omitted.
For infants who had been weaned, information was not collected on the types of food they were weaned onto, but data were available on consumption of foods in the 10 days prior to symptoms in cases (interview in controls), but none were significantly
associated with
diarrhoeal disease (data not shown).
Breast feeding was
associated with significantly less
diarrhoeal disease, even in infants aged ⩾ 6 months.
Potential confounding factors
associated with
diarrhoeal disease (p < 0.10) were included in a multivariate model where infant feeding was the main exposure.
In the unadjusted analysis,
diarrhoeal disease was significantly
associated with lower social class, living in rented council accommodation, not having access to a food mixer, having contact with a person with diarrhoea / vomiting within or outside the household, formula feeding, and, in infants not being breast fed, not using chemicals / steam to sterilise bottles (table 1).
Receiving no breast milk and not receiving exclusive breast milk were both significantly
associated with an increase in
diarrhoeal disease (adjusted OR = 2.74 and 3.62 respectively).
Importantly, we found that in infants currently formula fed, having been breast fed for at least six months was not
associated with less
diarrhoeal disease than having never been breast fed.
Further, in infants currently formula fed, having been breast fed for at least six months was not
associated with less
diarrhoeal disease than having never been breast fed (for 6 + months versus never breast fed, adjusted OR = 1.14, 95 % CI 0.38 to 3.40, p = 0.81).