Not exact matches
Risk factors include: 1) age (most people are diagnosed
in their 20s - 30s), 2) race or ethnicity (Caucasians have the highest risk, but IBD can occur
in any race; there's an even higher risk if you are of Ashkenazi Jewish descent), 3) family history (risk is higher if a close relative has the disease), 4) cigarette smoking (the most important controllable risk factor for developing CD), 5) nonsteroidal anti-inflammatory medications (includes ibuprofen [Advil, Motrin IB, others], naproxen sodium [Aleve],
diclofenac sodium [Voltaren], and others), and 6) where you live (you are more likely to develop IBD if you live
in an industrialized country).
«The data unequivocally show that
diclofenac is responsible for the vulture population decline
in Pakistan,» he says.
Yadav points out that
diclofenac is not widely used
in India, which also experienced a large vulture die - off.
The cause was eventually traced to
diclofenac, a veterinary anti-inflammatory drug that relieved pain
in cattle, but proved highly toxic to vultures.
In Nepal, undercover pharmacy checks have shown a dramatic decline in the availability of diclofenac since the nation's only zone was created in 2012, with none found inside the zone since 201
In Nepal, undercover pharmacy checks have shown a dramatic decline
in the availability of diclofenac since the nation's only zone was created in 2012, with none found inside the zone since 201
in the availability of
diclofenac since the nation's only zone was created
in 2012, with none found inside the zone since 201
in 2012, with none found inside the zone since 2014.
Eventually, governments
in the region moved to save vultures by banning veterinary uses of
diclofenac.
A 2004 study estimated that
diclofenac contamination of as few as one
in 760 cow carcasses is enough to drive down vulture numbers.
(
In 2017, Bangladesh became the first government to ban ketoprofen in addition to diclofenac, though only inside the safe zones
In 2017, Bangladesh became the first government to ban ketoprofen
in addition to diclofenac, though only inside the safe zones
in addition to
diclofenac, though only inside the safe zones.)
Some vultures can't metabolize
diclofenac, a painkiller that became widely used
in the 1990s to treat fevers, udder inflammation, and other aches and pains
in cattle.
The Oriental white - backed vulture has experienced a critical decline
in its numbers, thought to be due to the veterinary drug
diclofenac.
Studies
in India, Pakistan, and Nepal have found extensive evidence of
diclofenac, a non-steroidal anti-inflammatory analgesic,
in dead vultures.
The drug,
diclofenac, is commonly used to treat pain
in livestock.
In Spain, the authors of today's letter are urging the Spanish government to rescind
diclofenac's approval for veterinary use under «the precautionary principle, which was recognized as a fundamental element of environmental policy at the Rio Conference of 1992.»
In 2003, researchers fingered
diclofenac as the cause of the sudden and widespread disappearance of three of India's most common vultures: the white - backed, the slender - billed, and the Indian vulture.
Investigators conducted a 5 - week effectiveness study of
diclofenac topical gel, an NSAID,
in 44 patients with knee OA (i.e., arthritis caused by a breakdown of the lining of the joints).
Also, the anti-inflammatory drug
diclofenac bioaccumulates
in fish, but its impact is unclear, said Diana Aga, a chemistry professor and researcher at the University of Buffalo who studies emerging chemicals
in the Great Lakes.
Examples of drugs identified as high - potential agents within the Repurposing Drugs
in Oncology (ReDO) project include mebendazole, cimetidine, nitroglycerin,
diclofenac and clarithromycin, among others [3].
«Regardless of dose, the prescription drug
diclofenac is the most effective drug among painkillers
in terms of improving pain and function
in osteoarthritis,» said lead researcher Dr. Sven Trelle.
«If you are thinking of using a painkiller for osteoarthritis, you should consider
diclofenac,» Trelle said, but also keep
in mind that like most NSAIDs the drug increases the risk for heart disease and death.
A published human trial of BCM - 95 curcumin compared it to the prescription NSAID
diclofenac sodium
in rheumatoid arthritis.
In practical terms, the chance of you hurting yourself with a drug like diclofenac sodium — ironically, in an attempt to reduce pain — as compared to a simple kitchen spice like turmeric, is infinitely highe
In practical terms, the chance of you hurting yourself with a drug like
diclofenac sodium — ironically,
in an attempt to reduce pain — as compared to a simple kitchen spice like turmeric, is infinitely highe
in an attempt to reduce pain — as compared to a simple kitchen spice like turmeric, is infinitely higher.
Both the curcumin and curcumin - plus -
diclofenac group experienced reductions
in their erythrocyte sedimentation rate of 11.2 and 13.3 percent respectively, while the group taking only the
diclofenac had a mere 8.3 percent reduction
in sedimentation rate.
The most common analgesics currently used
in rabbits include butorphanol, buprenorphine and nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, carprofen,
diclofenac, flunixin, ibuprofen, indomethacin, ketoprofen, meloxicam, acetominophen and piroxicam.
Indian vultures have suffered population declines of 97 - 99 %, with the annual rate of decline of 16 %
in the first part of this century, all because of exposure to the drug
diclofenac, given to farm animals to reduce joint pain and allow them to work longer.