Sentences with phrase «dietary trial in»

Targeting insulin inhibition as a metabolic therapy in advanced cancer: a pilot safety and feasibility dietary trial in 10 patients.

Eugene Fine was also there with a poster on his just published pilot study on ketogenic diets and cancer — «Targeting insulin inhibition as a metabolic therapy in advanced cancer: A pilot safety and feasibility dietary trial in 10 patients.»

Not exact matches

That's just one of the reasons FloraGLO is trusted most by doctors — based on the results of the National Disease and Therapeutic Index syndicated report among physicians who recommend a dietary supplement with lutein for eye health between September 2009 and September 2010 — and is the brand being used in the National Eye Institute's AREDS 2 trial.

It's naturally rich in dietary fiber, particularly soluble fiber which was shown in clinical trials helps fight diabetes.

Screening, random assignment, and follow - up of the study participants in the Swedish dietary and exercise behavior - modification intervention trial in lactating overweight and obese women.

In the randomized controlled trial, 38 men with abdominal obesity followed a dietary pattern high in either carbohydrates or fat, of which about half was saturateIn the randomized controlled trial, 38 men with abdominal obesity followed a dietary pattern high in either carbohydrates or fat, of which about half was saturatein either carbohydrates or fat, of which about half was saturated.

In an effort to find out, Stephen P. Juraschek, M.D., Ph.D., research and clinical fellow in general internal medicine at the Johns Hopkins University School of Medicine, and his colleagues used data from the DASH (Dietary Approaches to Stop Hypertension) clinical trial, a widely popular and often - cited study whose results were first published in 199In an effort to find out, Stephen P. Juraschek, M.D., Ph.D., research and clinical fellow in general internal medicine at the Johns Hopkins University School of Medicine, and his colleagues used data from the DASH (Dietary Approaches to Stop Hypertension) clinical trial, a widely popular and often - cited study whose results were first published in 199in general internal medicine at the Johns Hopkins University School of Medicine, and his colleagues used data from the DASH (Dietary Approaches to Stop Hypertension) clinical trial, a widely popular and often - cited study whose results were first published in 199in 1997.

It typically takes many years to initiate such trials because of the stringent safety testing that must be done before testing in humans begins, but Reynolds said it may be possible to move faster as the therapy only involves modifying a patient's dietary intake and supplementing with a medium - chain triglyceride oil, both of which have no known side effects.

Furthermore, dietary antioxidants have failed as anticancer agents in clinical trials (4).

Results of the randomized clinical trial of the dietary combination, conducted by researchers at the Johns Hopkins University School of Medicine, were published in the Nov. 12 issue of Journal of the American College of Cardiology.

Their detailed review also assesses the dietary interventions that are being implemented in preclinical and clinical trials.

Overall, the investigators found that foods, nutrients, dietary patterns or supplement use assessed before the start of the clinical trial had no measurable influence on the effectiveness of a multivitamin on CVD risk in middle - aged and older men.

«In the absence of such a trial, results of the PURE study argue against reduction of dietary sodium to currently recommended levels as an isolated public health recommendation,» she said.

The article is entitled «A Randomized Crossover Trial of Dietary Sodium Restriction in Stage 3 - 4 Chronic Kidney Disease.»

Other evidence (including some from our own groups) suggests that the main dietary culprit for excess weight in society remains excess fat intake, not necessarily excess sugars, whilst trial evidence suggests all forms of diets work to lessen weight.

Hazard ratios (HRs) were estimated using Cox proportional hazards models stratified by age, prior disease (if appropriate), and randomization status in the WHI dietary modification trial.

These unfavorable effects of n - 6 LA shown in the SDHS are consistent with two other randomized controlled trials, in which experimental dietary conditions selectively increased n - 6 LA in the place of SFAs by replacing animal fats and common margarines with corn oil.50 51 Together, these three trials provide a rare opportunity to evaluate the specific effects of increasing n - 6 LA without confounding from concurrent increases in n - 3 PUFAs.

Johnson GH, Fritsche K. Effect of dietary linoleic acid on markers of inflammation in healthy persons: a systematic review of randomized controlled trials.

In a randomized controlled trial published in BMC Medicine, depression sufferers with poor dietary habits were divided into two groupIn a randomized controlled trial published in BMC Medicine, depression sufferers with poor dietary habits were divided into two groupin BMC Medicine, depression sufferers with poor dietary habits were divided into two groups.

The first was a 2010 trial in the American Journal of Epidemiology that examined the effect of lifestyle and dietary factors on mortality in middle aged women.

27 Studies cited by the 2010 DGAC Report demonstrate varied metabolic responses to lowered dietary saturated fat, with certain subpopulations exhibiting adverse rather than improved health outcomes.3 Two recent comprehensive meta - analyses indicate that saturated fat is not linked to heart disease.28, 29 In fact, in a definitive review of forty - eight clinical trials, with over sixty - five thousand participants, the reduction or modification of dietary fat had no effect on mortality, cardiovascular mortality, heart attacks, stroke, cancer, or diabetes.30 Yet, avoiding saturated fat remains a cornerstone of national dietary guidancIn fact, in a definitive review of forty - eight clinical trials, with over sixty - five thousand participants, the reduction or modification of dietary fat had no effect on mortality, cardiovascular mortality, heart attacks, stroke, cancer, or diabetes.30 Yet, avoiding saturated fat remains a cornerstone of national dietary guidancin a definitive review of forty - eight clinical trials, with over sixty - five thousand participants, the reduction or modification of dietary fat had no effect on mortality, cardiovascular mortality, heart attacks, stroke, cancer, or diabetes.30 Yet, avoiding saturated fat remains a cornerstone of national dietary guidance.

The Canadian Trial of Carbohydrates in Diabetes (CCD), a 1 - y controlled trial of low - glycemic - index dietary carbohydrate in type 2 diabetes: no effect on glycated hemoglobin but reduction in C - reactive prTrial of Carbohydrates in Diabetes (CCD), a 1 - y controlled trial of low - glycemic - index dietary carbohydrate in type 2 diabetes: no effect on glycated hemoglobin but reduction in C - reactive prtrial of low - glycemic - index dietary carbohydrate in type 2 diabetes: no effect on glycated hemoglobin but reduction in C - reactive protein

Conversely, in 5 trials, yoga was reported as having no effect on systolic BP compared to dietary modification, enhanced usual care, relaxation or physical exercise.

A systematic review of all the dietary trials showed that much of the benefits of a low carbohydrate approach faded by 1 year.In the follow up to the DIRECT study, it was found that by 12 months, weight had started to regain in all patients, including the low carbohydrate group.

«In summary, randomized controlled trials that lowered intake of dietary saturated fat and replaced it with polyunsaturated vegetable oil reduced CVD by?

Some important studies include: • Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men (1976) • Response of non-insulin-dependent diabetic patients to an intensive program of diet and exercise (1982) • Diet and exercise in the treatment of NIDDM: The need for early emphasis (1994) • Toward improved management of NIDDM: A randomized, controlled, pilot intervention using a low fat, vegetarian diet (1999) • The effects of a low - fat, plant - based dietary intervention on body weight, metabolism, and insulin sensitivity (2005) • A low - fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes (2006) • A low - fat vegan diet and a conventional diabetes diet in the treatment of type 2 diabetes: a randomized, controlled, 74 - wk clinical trial (2009) • Vegetarian diet improves insulin resistance and oxidative stress markers more than conventional diet in subjects with Type 2 diabetes (2011) • Glycemic and cardiovascular parameters improved in type 2 diabetes with the high nutrient density (HND) diet (2012)

All studies had to be listed in the Cochrane Central Register of Controlled Trials, and the dietary interventions observed had to last at least 4 weeks.

Other publications on cancer chemoprevention include Comprehensive review of cancer chemopreventive agents evaluated in experimental carcinogenesis models and clinical trials, Chemopreventive effects of natural dietary compounds on cancer development, Organosulfur compounds in cancer chemoprevention, Cancer prevention by natural compounds, Cruciferous vegetables and cancer prevention, Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis, Cruciferous vegetables: cancer protective mechanisms of glucosinolate hydrolysis products and selenium.

Long term experience 1981 High carbohydrate high in fibre diet in diabetes 2004 Dietary management of diabetes mellitus in India and South East Asia 2014 Effect of brown rice, white rice, and brown rice with legumes on blood glucose and insulin responses in overweight Asian Indians: a randomized controlled trial

CAAT is proving effect in trials and case studies, and oncologists are relatively willing to recommend the treatment as it is non-invasive, consisting of predominantly dietary changes, supplements and foodstuffs added, especially those that have an antioxidant effect; certain foods containing «harmful» amino acids reduced or removed from the regimen altogether.

1935 Effects of the high carbohydrate - low calorie diet upon carbohydrate tolerance in diabetes mellitus 1955 Low - fat diet and therapeutic doses of insulin in diabetes mellitus 1958 Effect of rice diet on diabetes mellitus associated with vascular disease 1976 Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men 1977 Effect of carbohydrate restriction and high carbohydrates diets on men with chemical diabetes 1979 High - carbohydrate, high - fiber diets for insulin - treated men with diabetes mellitus 1981 High carbohydrate high in fibre diet in diabetes 1982 Response of non-insulin-dependent diabetic patients to an intensive program of diet and exercise 1983 Long - term use of a high - complex - carbohydrate, high - fiber, low - fat diet and exercise in the treatment of NIDDM patients 1994 Diet and exercise in the treatment of NIDDM: the need for early emphasis 1999 Toward improved management of NIDDM: A randomized, controlled, pilot intervention using a lowfat, vegetarian diet 2005 The effects of a low - fat, plant - based dietary intervention on body weight, metabolism, and insulin sensitivity 2006 A low - fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes 2006 Effect of short ‐ term Pritikin diet therapy on the metabolic syndrome 2009 A low - fat vegan diet and a conventional diabetes diet in the treatment of type 2 diabetes: a randomized, controlled, 74 - wk clinical trial

Again, data from randomized clinical trials in children as young as 7 months of age have demonstrated that these dietary recommendations are safe and do not interfere with normal growth, development, and sexual maturation.44, 46,48

The new SMILES trial was presented at the conference: the first randomized controlled diet depression study where ONE THIRD of the dietary intervention group saw improvements in their depression and anxiety symptoms by switching from processed / junk food to real food with no specific dietary restrictions.

In a multicenter trial in Spain, we randomly assigned participants who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fatIn a multicenter trial in Spain, we randomly assigned participants who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fatin Spain, we randomly assigned participants who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fat).

In humans, data collected from 38 different trials of food consumption that used widely varying intakes of protein, from 8 to 54 % of energy, showed: «Percent dietary protein was negatively associated with total energy intake (F = 6.9, P < 0.0001) irrespective of whether carbohydrate (F = 0, P = 0.7) or fat (F = 0, P = 0.5) were the diluents of protein.

The scientist in me hopes to see randomized, controlled trials comparing the ability of raw milk, pasteurized milk, UHT - treated milk, and milk - free diets to prevent and treat asthma, and comparing their effects with and without other nutritional treatments, such as the inclusion of liver, bone broth, and other nutrient - dense foods, and dietary or lifestyle interventions aimed at increasing the metabolic rate.

, Role of Dietary Fats in Modulating Cardiometabolic Risk During Moderate Weight Gain: A Randomized Double - Blind Overfeeding Trial (LIPOGAIN Study), 2014

Human trials have shown that oatmeal, rich in beta - glucans, may increase satiety and reduce appetite when compared to a ready - to - eat breakfast cereal and other types of dietary fiber (13, 14, 79, 80).

In the ensuing years, many researchers published trials of dietary fat substitution, but most of them were poorly designed and poorly controlled.

The findings add to «a growing body of evidence from clinical trials that have found little cardiovascular benefit from moderate levels of dietary supplementation,» the researchers wrote in the journal article.

In a clinical trial, the study controls the dietary intake, which is more complicated than in observational studies where the participants control their own dieIn a clinical trial, the study controls the dietary intake, which is more complicated than in observational studies where the participants control their own diein observational studies where the participants control their own diet.

Long - term effects of 2 energy - restricted diets differing in glycemic load on dietary adherence, body composition, and metabolism in CALERIE: a 1 - y randomized controlled trial.

Subjects (n = 133) were enrolled in the Dietary Approaches to Stop Hypertension (DASH) trial in order to determine the effect of diet on blood pressure.

The first: «Targeted alteration of dietary n - 3 and n - 6 fatty acids for the treatment of chronic headaches: A randomized trial» [full text here] and the second: «Targeted alterations in dietary n - 3 and n - 6 fatty acids improve life functioning and reduce psychological distress among chronic headache patients: secondary analysis of a randomized trial.»

The effect of dietary flaxseed on improving symptoms of cardiovascular disease in patients with peripheral artery disease: Rationale and design of the FLAX - PAD randomized controlled trial.

In light of this evidence from randomized controlled trials, dietary guidelines should be re-visited advocating a healthy low carbohydrate dietary pattern as an alternative dietary strategy for the prevention of obesity and cardiovascular disease risk factors.»

Although short - term randomized clinical trials have shown a beneficial effect of high protein intake, 3,4,20,21 the long - term health consequences of protein intake remain controversial.8,9,22 - 25 In a randomized clinical trial with a 2 - year intervention, 4 calorie - restricted diets with different macronutrient compositions did not show a difference in the effects on weight loss or on improvement of lipid profiles and insulin levels.26 When protein is substituted for other macronutrients, the dietary source of protein appears to be a critical determinant of the outcomIn a randomized clinical trial with a 2 - year intervention, 4 calorie - restricted diets with different macronutrient compositions did not show a difference in the effects on weight loss or on improvement of lipid profiles and insulin levels.26 When protein is substituted for other macronutrients, the dietary source of protein appears to be a critical determinant of the outcomin the effects on weight loss or on improvement of lipid profiles and insulin levels.26 When protein is substituted for other macronutrients, the dietary source of protein appears to be a critical determinant of the outcome.

This session will review her personal story and the dietary and lifestyle interventions she uses in her clinics and in the clinical trials she conducts in the setting of progressive and relapsing - remitting multiple sclerosis.

In a prospective, randomized, controlled trial with a low fat and a low fat plus high Dietary Fiber groups, the group consuming high Dietary Fiber exhibited a greater average reduction (13 percent) in serum total cholesterol concentration than the low fat (9 percent) and the usual diet (7 percent) groups (Anderson et al., 1992aIn a prospective, randomized, controlled trial with a low fat and a low fat plus high Dietary Fiber groups, the group consuming high Dietary Fiber exhibited a greater average reduction (13 percent) in serum total cholesterol concentration than the low fat (9 percent) and the usual diet (7 percent) groups (Anderson et al., 1992ain serum total cholesterol concentration than the low fat (9 percent) and the usual diet (7 percent) groups (Anderson et al., 1992a).

In this randomized 2 by 2 factorial trial that tested the effects of (1) increased fruit and vegetable intake and (2) reduced fat intake, alone or combined, participants were counseled to maintain their energy intake while they made the dietary changes relevant to their assigned group.