Humans and chimps each have somewhere between 20,000 and 30,000 genes, so there are likely to be nucleotide
differences in every single gene.
Not exact matches
The Irish wolfhound stands a metre high and weighs as much as 30 chihuahuas, but the
difference in size between the two is due to a
single gene, which comes
in one form
in the large animal and another
in the small.
In many cases, the activity of particular genes was tied to a single genetic variant, with strong differences in frequency between European and African population
In many cases, the activity of particular
genes was tied to a
single genetic variant, with strong
differences in frequency between European and African population
in frequency between European and African populations.
But
in genes,
differences as small as a point mutation — the alteration of a
single base pair — can lead to disease.
They have discovered that a
single amino acid
difference in the structure of histone H3.3 enables it to serve as a kind of memory device for the cell, marking
genes that need to remain active.
The team found that a
single polymorphism (a
difference in one «letter» of the sequence)
in the BDNF
gene accounted for significant
differences in intelligence among those with similar injuries and comparable intelligence before being injured.
But many researchers, including Keller and Ross, didn't think variations
in a
single gene could account for all the
differences in size, fertility, odor, and aggression that separated the two ant groups.
The authors find that evolved
differences in UV absorbance between the species could be explained by changes to a
single gene, MYB - FL.
Mutations
in the
genes SLC24A5 and SLC45A2 are largely responsible for European pigmentation, showing only
single amino acid
differences between Europeans and West Africans.
No significant
differences were seen between the normoxic and hypoxic anoikis - resistant populations collected from MCF7 cells and a
single significant
gene change (PIP) was seen
in T47D (Table 1) suggesting that the CSC - enriched population remains virtually unchanged following hypoxic culture and the increase
in MFC, HFC, and tumor initiating cells is, therefore, due to expansion of the population, perhaps by increased symmetric self - renewal of the CSC or de-differentiation of early progenitor cells, rather than simply the acquisition of anoikis resistance
in non-CSC.
Genome - wide association studies use «genechip» technology to identify genetic variants (
single gene polymorphisms or «SNPs») that could explain
differences in health between individuals.