We compared the transcriptomes from VNO and OM of both male and female mice to assess whether
differences in gene expression in these tissues could underpin sexually dimorphic behaviors [17].
To see what genes might be involved in this increased aggression, the team used microarrays to look for
differences in gene expression in fly brains.
A baseline study shows major
differences in gene expression in the hypothalamus and pituitary between male and female pigeons.
He has been studying
differences in gene expression in infected and uninfected plants and finds that the fungus seems to increase the activity of genes involved in seed production.
Not exact matches
Maternal care,
gene expression, and the transmission of individual
differences in stress reactivity across generations.
They examined whether there were
differences in the composition of the breast milks» microRNAs, snippets of RNA that affect
gene expression and can be passed to the infant.
«Human and chimpanzee
genes differ very little, so one hypothesis
in evolutionary genomics holds that humans and chimpanzees are so phenotypically different because of
differences in the way they regulate
gene expression.
We wanted to understand what types of
differences are always there, what is causing them, and what they mean,» says Juan Carlos Izpisua Belmonte, a professor
in Salk's
Gene Expression Laboratory and co-senior author, with Kelly Frazer of the University of California, San Diego, on the new paper, which was published
in Cell Stem Cell
in April 2017.
Prof. Khatri and his team studied the way the immune system responds to infection by looking at
gene expression — which
genes are active and which are not — and whether there are
differences in patients with malaria compared to other infectious diseases.
In the healthy weight subjects, the difference in gene expressions were not significan
In the healthy weight subjects, the
difference in gene expressions were not significan
in gene expressions were not significant.
For example, the nuclei
in the centers of the mutant organoids moved more slowly, and we saw significant
differences in gene expression.»
It isn't clear exactly why the
differences fade, Hochedlinger says, but it may be that the
expression of embryonic
genes is strengthened as the cells grow
in culture, gradually overwriting the cells» old
gene -
expression patterns.
«The 20 - year
difference in expression of the
gene abnormality shows the devastating consequences of recent environmental factors, such as eating high - glycaemic foods and a lack of exercise,» Froguel says.
An analysis of
gene expression of the known fungal partner
in the two species showed no
differences.
Their results showed that both forms of RP had clear
differences in gene expression compared to normal retinas.
When the researchers started taking weeds out of the corn at early points, such as when the corn had as few as two and four leaves, they still saw
differences in gene expression when compared to corn without weeds.
«There was also a big
difference in gene expression of a specific enzyme called nicotinamide N - methyltransferase.»
The researchers also found
differences in microRNA
expression in bipolar cells — tiny fragments of RNA that play key roles
in the «reading» of
genes.
When the team measured
gene expression first
in the stem cells, and then re-evaluated the cells once they had become neurons, very specific
differences emerged between the cells derived from bipolar disorder patients and those without the condition.
What we were surprised to find out was that the real
differences we could detect
in terms of when we did the swap experiments to say which yeast could outperform the other — what we learned was that the GAL1
gene, that the part [of] that, the DNA sequence is outside of the GAL1
gene, it acts as a switch to turn up or turn down GAL1
expression, that had evolved considerably from the ancestral situation; and same for the GAL3.And then what had happened was that each function had been optimized, that GAL3 had sort have been tuned to be sort of a loosely regulated kind of available anytime sensor of galactose and GAL1 had evolved to be an incredibly tightly regulated,
in fact, it's the most tightly regulated
gene you know of
in yeast.
«We are currently
in the process of identifying
differences in gene expression and neuroanatomy
in these birds to better understand the neural mechanisms of these cognitive deficits,» says Roth.
Most importantly, plants from the spring sites had
differences in the
expression of hundreds of
genes.
Despite
differences in brain size, the researchers found striking similarities between primate species of
gene expression in 16 regions of the brain — even
in the prefrontal cortex, the seat of higher order learning that most distinguishes humans from other apes.
Differences between populations
in gene expression have not been well characterized before.
In this case, the study authors say, differences in gene expression over the course of a day may cause a person's heart to heal more quickly in the afternoon than in the mornin
In this case, the study authors say,
differences in gene expression over the course of a day may cause a person's heart to heal more quickly in the afternoon than in the mornin
in gene expression over the course of a day may cause a person's heart to heal more quickly
in the afternoon than in the mornin
in the afternoon than
in the mornin
in the morning.
A large body of research has reported that Nanog is allelically regulated — that is, only one copy of the
gene is expressed at any given time — and fluctuations
in its
expression are responsible for the
differences seen
in individual embryonic stem (ES) cells» predilection to differentiate into more specialized cells.
«By looking comprehensively at
gene expression within cells, we can now spot numerous important
differences in complex tissues like the brain that are invisible today,» said George Church, Ph.D., a Core Faculty member at the Wyss Institute and Professor of Genetics at Harvard Medical School.
Rather than listing specific
genes that manifest themselves differently, or are differentially expressed, between queens and workers, the team looked for
genes with similar
expression patterns across samples that may be involved
in maintaining the structural, behavioural and functional
differences observed between queens and workers.
This information is not only important because it can now help scientists try to understand how the
differences between queen and worker may arise through interactions among
genes, but also for the evolution of ants, and
in the evolution of
gene expression more generally.
The researchers» results suggest that structural and functional
differences between queens and workers result from the differential
expression of evolutionary conserved sets of
genes, or
genes that are basically expressed
in the same manner throughout evolution among all ant species.
The MD Anderson team also is looking at
gene expression, mutations and immune profiling to identify potential
differences in melanoma
in obese and non-obese patients and developing preclinical models.
It's the first time scientists have shown
in selectively bred animals that the propensity for addiction is linked to
differences in expression of
genes for specific molecules
in a specific brain region.
The new study, published this month by Molecular Autism
in a special issue on sex
differences in autism, further shows a stronger correlation between the
expression level of RORA and that of
genes regulated by RORA
in males.
The authors are now working to understand how selection acts differently on males and females, and how this leads to
differences in gene expression between the sexes.
In fact, the researchers found gene expression differences between ASD and non-ASD in genes related to translation and immune / inflammation functions, as well as cell adhesion and cell cycl
In fact, the researchers found
gene expression differences between ASD and non-ASD
in genes related to translation and immune / inflammation functions, as well as cell adhesion and cell cycl
in genes related to translation and immune / inflammation functions, as well as cell adhesion and cell cycle.
For example, the researchers were able to identify previously unknown
gene expression differences between the neural stem cells that give rise to the brain's deep structures versus its neocortical surface, and to show that molecular signatures of different neural cell types arise much earlier
in brain development than previously realized.
In these images of rat brains, differences in gene expression of genes for fibroblast growth factor 2 (FGF2, top set) and dopamine 2 receptor (D2, bottom sett) can be seen in rats of two breeds before (left) and after (right) cocaine exposur
In these images of rat brains,
differences in gene expression of genes for fibroblast growth factor 2 (FGF2, top set) and dopamine 2 receptor (D2, bottom sett) can be seen in rats of two breeds before (left) and after (right) cocaine exposur
in gene expression of
genes for fibroblast growth factor 2 (FGF2, top set) and dopamine 2 receptor (D2, bottom sett) can be seen
in rats of two breeds before (left) and after (right) cocaine exposur
in rats of two breeds before (left) and after (right) cocaine exposure.
However, although fetal tissues from the mother mouse's grandchildren also had similar changes
in gene expression, surprisingly, the DNA
in these tissues did not carry these methylation
differences.
The team found deep conservation of certain processes that likely reflects similar underlying regulatory processes between mouse and man, but there were also significant
differences in gene expression during kidney development, as well as
in the timing, scale, organization, and molecular profile of key cell types and cell structures.
They compared space - flown endothelial cells to endothelial cells cultured under normal gravity, looking for
differences in gene expression and / or
in the profile of secreted proteins.
These
gene expression variances could explain the
differences in disease risks, or disease symptoms, between males and females, Clark says.
«There are incredible
differences in gene expression, especially
in the pituitary,» Calisi said.
Among older sets of twins, however, significant
differences in the
gene -
expression portraits were apparent for 35 percent of the study group.
Pääbo has also found that
differences in gene expression (how active a
gene is) may have played a role
in creating the gap between chimp and human brains.
Differences in gene expression may thus explain how largely similar genomes create such different organisms.
The team suspects the
difference may be due to the
expression of a
gene that codes for a growth factor called bone morphogenetic protein 2 (Bmp2);
expression was 30 % higher
in the developing forelimbs of bats than it was
in mice.
We know that all
differences between these appendages are specified by the
expression of the Hox
gene Ultrabithoax (Ubx)
in the haltere and its absence from the wing (1).
Differences in gene expression may have given us bigger brains, but
in this movie scene, the chimp comes out on top.
****, significant
differences in dosing regimen on the
expression of each membrane transporter
gene were observed as assessed by two - way ANOVA analysis, P <.0001; ***, significantly different by ANOVA, P <.001; **, significant
differences by ANOVA, P <.01; *, significant
differences by ANOVA, P <.1.
By evaluating DNA methylation, the researchers discovered
differences in gene networks and
gene expression linked to the central nervous system and interactions with HIV that appeared uniquely
in monocytes of HIV infected study participants with cognitive impairment.