An engineer designing a protein that has 1000 amino acids may choose among some 101300
different amino acid sequences.
Not exact matches
When strung together in a
sequence,
amino acids create peptides and proteins with
different 3D structures and, consequently,
different biological functions.
Naturally occurring peptides can be composed of 20
different amino acids, so there is a great deal of possible variation in their
sequences.
Amino acids come in 20
different varieties; proteins typically contain between 100 and a few thousand linked in
different sequences.
«What's critical with this and what has never been done before is that a single peptide
sequence will work against the toxic versions of a number of
different amyloid proteins and peptides, regardless of their
amino acid sequence or the normal 3 - D structures.»
When they compared the
amino acid sequence of naked mole rat protein, the researchers found that three of these protein building blocks were
different from the rat version and one was also
different from the same protein in other mole rats.
Prions can exist as distinct strains — proteins that have the same
sequence of
amino acids but misfold in
different ways and have distinct biological behaviours, much as
different strains of a pathogenic virus can be aggressive or weak.
For dog - related rabies, host jumping was linked to multiple evolutionary patterns, such as parallel changes in
amino acid sequences between
different host species.
«For dog - related rabies, host jumping was linked to multiple evolutionary patterns, such as parallel changes in
amino acid sequences between
different host species, suggesting that dog - related rabies may not need to evolve much to jump to new carnivore hosts.»
Analysis of the DNA and encoded
amino acid sequences of A14 and B9 revealed that the first two are clonal variants which aligned most closely to the germ line denoted VHH Vg (T Verrips, unpublished data) and that the
sequence of B21 is highly divergent from both and also aligns to a
different germ line V gene
sequence Vu.
Although this intriguing possibility remains theoretical, the similarities in the
amino acid sequences of NGF and insulin are not great enough to result in any similarity of function: the two molecules have completely
different target cells and biological activities.
protein: A molecule made up of a
sequence of
amino acids (there are 23
different amino acids).
Dazl homologs contain slightly
different consensus
sequences for both RNP2 (VFVGGI) and RNP1 (KGYGFVSF), have distinct
sequences surrounding the RNPs, and have a conserved deletion of two
amino acids (Figure S2)[35].
Protein the building blocks of cells — each protein molecule is composed of its own unique
sequence of
amino acids (there are 20
different kinds of
amino acids in the human body).
The particular
sequence of
amino acids in the chain is what makes one protein
different from another.