Sentences with phrase «different aneuploidy»
By identifying phenotypes that are shared among tumors with different aneuploidies, we hope to discover pathways that can be manipulated to selectively eliminate aneuploid cells or to block aneuploidy's non-cell autonomous effects.
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PGS for gay couples helps determine if any of the embryos have extra or missing chromosomes, known as aneuploidy, or if any chromosomes have translocated, which means a piece of a chromosome has broken off and reattached itself to a different part of the chromosome or even to another chromosome.
«The organization of cell colonies and phenotypic switching between different types of colonies becomes a lot more flexible and rapid with reversible aneuploidy than if it depended on random mutations in the genes,» Skupin says.
The team's work highlights this by presenting a comprehensive view of genome evolution on many different levels (e.g., differences in ploidy, aneuploidy, genetic variants, hybridization, and introgressions) that is difficult to obtain at the same scale and accuracy for other eukaryotic organisms.
Here we use two different mutant conditions to address the consequences of aneuploidy during tissue development and homeostasis in Drosophila.
The alternation of two life stages in different environments (extracellular promastigotes and intracellular amastigotes) offers a unique opportunity to study the impact of environment on aneuploidy and gene expression.