Women need daily doses of the antiviral medication Truvada to prevent HIV infection while men only need two doses per week due to the way the drug accumulates
in different body tissues, according to a new study from pharmacy researchers the University of North Carolina at Chapel Hill.
Our Areas of Interest IFATS current scientific areas of interest relate to facilitating the development of treatments for excess body fat, the generation of new fat tissue for reconstruction after cancer or birth - related defects and the use of adipose tissue as a source of mesenchymal stem cells that have the potential to regenerate and
repair different body tissues.
They counted the numbers of APs and ALs
in different body tissues — intestine, muscle, pharynx (i.e., the animal's foregut), and neurons — at different time points during the adult life of C. elegans, and used chemical blockers to learn more about the dynamics of the process.
They built a new software tool called MIxT (Matched Interactions across Tissues) that uses computational and statistical methods to find and investigate links between gene expression in
different body tissues.
In addition, drawing on earlier work, they determined that these effects varied depending on the location of the infection — leading them to the conclusion that IL - 8 monomers and dimers interact differently with GAGs in
different body tissues.