The researchers, led by Olli Kallioniemi, Director of SciLifeLab and faculty at Karolinska Institutet / SciLifeLab, used exome and amplicon sequencing to compare biopsies from three
different bone marrow compartments of two patients.
Not exact matches
Our menu has included items such as locally sourced Niman Ranch flank steak with asparagus and fingerling potatoes and touches of ricotta and fried
bone marrow paired with a glass of the Ruth Lewandowski 2012 Boaz (produced by Pago's own sommelier, Evan Lewandowski), or carrots presented five
different ways as a tasting appetizer with a glass of the 2010 L'Hereu Cava, or the famous «Pago Burger» — a mix of ground chuck, short rib and brisket in the succulent burger patty, topped high with artisanal bacon, Gruyere cheese, roasted mushrooms, pickled red onion and kale, on a toasted brioche bun slathered with black garlic aioli and Dijon vinaigrette — which has been written about at length in the local and national press.
These cells, which can become several
different types of blood cells, are similar to the specialized stem cells found in
bone marrow that can churn out new blood cells.
The project's goals were to explore and describe the range of epigenetic changes that take place in
bone marrow as stem cells develop into
different types of mature blood cell.
«There is a school of pessimists who believe that because of costs it will never materialize on a practice level, but I've heard that all my life about
different areas of medicine including
bone marrow transplants in the «60s.»
One single stem cell from the
bone marrow is not going to be able to treat disorders as
different as Alzheimer's disease and rheumatoid arthritis,» he says.
Bone marrow biopsies often produce limited numbers of tumor cells to test — as few as 50,000 tumor cells in this study — but for this technique that is enough to test many
different drugs and drug combinations.
Because
bone marrow, colon, and liver are significantly
different tissues, the investigators believe the pathway by which SW033291 speeds tissue regeneration is likely to work as well for treating diseases of many other tissues of the body.
«Our approach represents a
different way of looking at leukemia and considers the entire
bone marrow as an ecosystem, rather than the traditional approach of studying and trying to directly kill the diseased cells themselves,» said Allison Boyd, postdoctoral fellow with the research institute and first author of the study.
«Our group pioneered the development of cell culture technology for harvesting large numbers of stem cells from human
bone marrow and human umbilical cord blood,» Dr. Yeh said, noting that stem cells from these two sources are abundant and can be guided into
different types of cells using tissue engineering.
Bone marrow produces around 10
different types of blood cell, each with
different functions.
Leukemia starts in the «hematopoietic» stem cells in the
bone marrow that give rise to all the
different kinds of mature blood cells.
In this study, the ALS mice were given intravenous treatments of one of three
different doses of the
bone marrow stem cells.
For example, when the team independently analyzed datasets of the same
bone -
marrow stem cells, produced by two separate labs, they obtained strikingly
different results.
Previously Dr. Martini worked at Shire plc in Lexington, Mass., as Senior Director of Discovery Biology and Translational Research, Mass., focusing on fibrotic diseases of muscle, kidney, skin, lung,
bone marrow and metabolic liver diseases, with particular emphasis on
different therapeutic modalities for pathway modulation.
In the COBRE for Stem Cell Biology, Brown and Rhode Island Hospital researcher Dr. Jason Aliotta is studying the role, for better and for worse, of
different extracellular vesicles — blobs of material shed by cells — in mediating the production of harmful cells in
bone marrow.
There are many
different types of adult stem cells: umbilical cord blood stem cells,
bone marrow stem cells, mesenchymal stem cells, endothelial stem cells, cardiac stem cells, muscle stem cells, and others.
B cells (bursal or
bone marrow - derived cells) are lymphocytes that play a pivotal role in the adaptive immune system and disruption of B cell function is a common hallmark of many
different diseases.
Since 2005 his group is working on the immunomodulatory activities of human mesenchymal stem cells isolated from
different sources —
bone marrow, adipose tissue, endometrium, decidua.
Human embryonic stem cells can turn into a variety of
different cell types, including (A) gut, (B) neural cells, (C)
bone marrow cells, (D) cartilage, (E) muscle, and (F) kidney cells.
Our initial studies were on characterization of
different adult neural stem cell types from murine and human brain and human
bone marrow.
Microarray profiling using the Affymetrix Mouse Genome 430 2.0 array, defines sets of genes that are specific to
bone marrow - derived hematopoietic stem cells and their
different immunological progeny.
To confirm the finding, normal
bone marrow cells were exposed to either IMGN632 or X-ADC for 72 hours at a concentration highly active against AML cells (100 pM), and the degree of caspase 3 activation, a marker of apoptosis, in
different cell populations was assessed by flow cytometry (supplemental Figure 4).
There are many
different subtypes of NHL, and they often show up in the form of an enlarged lymph node — although lymphomas can also start in other lymphatic tissue in the spleen,
bone marrow, tonsils, or digestive tract, among other places, according to the American Cancer Society (ACS).
It can be made with
different animal
bones (some with fatty
marrow, some without), with
different added flavors (like onions and herbs) and with
different cooking methods (five hours of simmering versus 24 hours or more).
Bone broth made with several different cuts of bone meat, such as leg bones and joints, will have a boost from bone marrow in the soup
Bone broth made with several
different cuts of
bone meat, such as leg bones and joints, will have a boost from bone marrow in the soup
bone meat, such as leg
bones and joints, will have a boost from
bone marrow in the soup
bone marrow in the soup pot.
* [4]
Bone,
marrow and cartilage was no
different.
I started to prepare my own home - made
bone broth with grass - fed organic beef -
marrow bones and New Zealand lamb
bones, and make soups for her with lamb meat (NZ) mostly (and lots of
different veggies).
«In the dish, you only have a select subgroup of immune system cells versus the mouse, where all of these cells were interacting and living in correct tissues and developing in
different areas like
bone marrow and spleen.»
Lipman wants to get to know his new «family» before he makes such an important request of them as to donate some
bone marrow, but he soon discovers that he and Sheila's family are as
different as night and day; things aren't made any easier when Lipman becomes infatuated with Maureen (Amy Robbins), Derek's ex-wife.
She would turn into a completely
different dog if she had a
marrow bone or a rawhide.
The total number of cells and the relative percentages of the
different types of white blood cells can help diagnose infection, stress, leukemia (a type of blood cancer) and other
bone marrow disorders.
We have characterized equine, canine and feline stem cells isolated from
different tissues (i.e. fat,
bone marrow, umbilical cord blood and umbilical cord tissue) with a focus on adult - derived mesenchymal stem cells.
It causes severe damage to dividing cells at
different sites, mostly in the
bone marrow and gastrointestinal tract, leaving dogs with gastrointestinal symptoms and suppressed immune systems.
Dogs are correlated with
different forms of leukemia disease, i.e. acute and chronic.The size of the population of white blood cells in the
bone marrow represents the acuteness of disease.
Blood and
bone marrow data from case examples will be used to demonstrate the correlation between the
different methods of performing biopsies.
Soak rawhide and long
marrow bones in
different flavored soups.
Sometimes
bone marrow or even just a
different type or brand of chew can give a dog an upset tummy.
But realize down to your
bone marrow that it's a
different answer in
different cases.