Sentences with phrase «different brain cell type»

It might be easier and more productive to use a different brain cell type called astrocytes.

Not exact matches

Only a special systemic order of atoms in certain molecules of different types of brain cells, steady activity of these cells and excitations coming from sensoric nerves and running to associative and motoric centers are the basis of the peculiarity of brain function.

In a new study published in Cell Reports, scientists at the Gladstone Institutes identified different types of neurons in a brain region called the reticular thalamus.

«Birds and primates share brain cell types linked to intelligence: Bird and reptile brains have a vastly different anatomy from mammalian brains, but contain cell types linked to mammalian cognitive abilities.»

«Each area of the brain is different with distinct cell types and connectivity, so if we can confirm that one area of circuitry is more involved in a particular symptom than another, we may eventually be able to treat a depression patient more efficiently than treating everyone the same way.»

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

These conditions are distinguished by the different types of brain nerve cells that are first affected and by the symptoms that first appear.

The Duke researchers who made this discovery say it may help explain how a relatively small number of genes can create the dazzling array of different cell types found in human brains and the nervous systems in other animals.

The olfactory system comprises six million to 10 million receptor cells (of which there are nearly 400 different types) and links to multiple brain structures and neural pathways, including those involved in memory, emotion and movement.

At Northwestern University, chemist Samuel Stupp and his research team have developed various types of amphiphile molecules (each end is chemically attracted to a different kind of material) that form self - assembling nanofibers, which in turn can prompt the regeneration of bone and brain cells.

«Disturbances to these processes may cause neuronal stem cells to develop into different types of cells or may cause neurons to migrate to different locations in the brain, changing neuronal circuitry and potentially leading to behavioral disorders like schizophrenia.»

Previous research had shown that nicotine seems to have conflicting effects on different types of nicotinic acetylcholine receptors, proteins on the surface of brain cells that respond to nicotine and the naturally occurring neurotransmitter acetylcholine.

To make sure she understood how nuclei, dendrites, and axons came together to form different types of brain cells, she pulled out her crochet hook and went to work.

Different abnormalities such as cleft palates, small skulls, and problems with higher brain function were seen depending on which cell types lacked Smc3 expression, but the phenotypes were similar to those seen in CdLS patients.

Different cell types — brain, blood, skin, gut etc. — all have unique and vital roles, yet they all start out the same.

Today, a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Partha Mitra describes a new mathematical model that combines large data sets to predict where different types of cells are located within the brain, based on their molecular identity.

The human brain consists of thousands of different types of nerve cells that are all formed out of what in simple terms can be described as immature stem cells.

One type of stem cell can produce multiple types of nerve cells at different stages of the brain's development.

Accurately labelling neurons with markers such as fluorescence, he says, will probably be the key challenge in the eventual goal of creating a «census» of different cell types in the brain.

To visualize different cell types in the brain, researchers often need genetic access to that cell — the ability to express a gene of interest only in, say, chandelier cells, but not neighboring neurons.

It has billions of parts, many used to activate and silence genes — an arrangement that allows individual cells to specialize as brain cells, heart cells and some 200 other different cell types.

In a paper published earlier this year in Molecular Cell, he and his team explored the activity of the FOS / JUN protein complex, which is expressed across many different cell types in the brain but appears to regulate unique programs in each different cell tCell, he and his team explored the activity of the FOS / JUN protein complex, which is expressed across many different cell types in the brain but appears to regulate unique programs in each different cell tcell types in the brain but appears to regulate unique programs in each different cell tcell type.

The number of receptors for the neurotransmitter in the brain amounts to 14, occurring in different cell types.

«We're interested in learning more about what other proteins LRP6 interacts with, as well as how it acts in different types of brain cells at different developmental stages of circuit development and refinement.»

Most of these trials involve stem cell - derived neural progenitor cells, which can turn into several different types of brain or spinal cord cells, or oligodendrocyte progenitor cells, which create the myelin sheaths that insulate and protect nerve cells.

Although both types of memory were laid down in the medial prefrontal cortex, they were stored along separate paths or axonal projections, which in turn linked to different brain regions (Cell, DOI: 10.1016 / j.cell.2016.05.010).

For example, the researchers were able to identify previously unknown gene expression differences between the neural stem cells that give rise to the brain's deep structures versus its neocortical surface, and to show that molecular signatures of different neural cell types arise much earlier in brain development than previously realized.

The different types of resulting brain cells were then stained in the fluorescent colors seen here.

Different types of tumors show a preference for specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.

Because stem cells have the ability to develop into many different cell types in the body, researchers at USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery & Brain Repair have focused on using stem cells to restore function lost through neurodegenerative disorders or injuries.

In the researchers» petri dishes, different cell types develop, connect into a network, exchange signals and produce metabolic products typical of the active brain.

To regain function, connections from the brain to the spinal cord must regrow, different types of immune cells have to clear the injury site, and stem cells in the spinal cord need to generate new nerve cells, which then connect to the muscles.

VIDEO: 3D images of different Sst interneurons, or type of nerve cell, in the outer shell, or cerebral cortex, of the mouse brain.

Most of these trials involve stem cell — derived neural progenitor cells, which can turn into several different types of brain or spinal cord cells, or oligodendrocyte progenitor cells, which create the myelin sheaths that insulate and protect nerve cells.

Different Sst interneurons, or type of nerve cell, in the outer shell, or cerebral cortex, of the mouse brain.

Because most immune cells typically can't get into the brain, microglia are adapted to perform multiple functions that are normally handled by several different types of immune cells.

The study represents the first salvo of a larger BRAIN Initiative - funded project in Kriegstein's lab to understand the thousands of different cell types that occupy the developing human BRAIN Initiative - funded project in Kriegstein's lab to understand the thousands of different cell types that occupy the developing human brainbrain

«We compiled a list of the proteins we thought Zika and similar viruses like dengue were using to get inside of cells, and then we looked to see which of these proteins were abundantly present in the different cell types of the developing brain,» said Pollen, who did the work with Tomasz Nowakowski, PhD, and a UCSF graduate student Carmen Sandoval - Espinosa, BS, both in Kriegstein's lab.

Their ambitions are bold: These marquee projects aim to map the brain in unprecedented detail, creating a picture of its different cell types, their activity and their interconnections.

«We are studying an ecosystem of different, but related, cell types in the brain,» Pollen said.

During the next two to three months, the cells began to organize themselves into layers and clusters of different cell types, paralleling what happens during the first eight to 10 weeks of human fetal brain development.

In addition, his lab has used cutting - edge molecular tools to dissect how the different cell types in the downstream brain regions work together with dopamine for control of actions.

The results suggest that brain tumours adapt their chemical reactions in very similar ways to survive in the brain, despite starting in very different types of cells and regions.

Double immunogold labeling in mouse brain is used to distinguish different cell types.

Our initial studies were on characterization of different adult neural stem cell types from murine and human brain and human bone marrow.

Sten Linnarsson (Karolinska Institutet / SciLifeLab), Joakim Lundeberg (KTH / SciLifeLab) and Mats Nilsson (Stockholm University / SciLifeLab) is leading the investigations, which aims to characterize cell types of brain, lung and heart tissue using single - cell RNA sequencing, and and make a three dimensional map of where the different cell types are located in the embryo.

Another consideration when developing drugs is that the particular brain cells we'd like to rescue in HD - neurons - are very different from other types of cells.

«Those profiles can tell you the different types of cancer; they can tell you the different types of cells; they can distinguish stem cells from other cells; and they can distinguish skin cells from brain cells.

Among these achievements are the development of new techniques for classifying different types of neurons; automated methods for creating wiring diagrams of the connections between cells in the mammalian brain; new ways of recording and manipulating the electrical activity of hundreds, even thousands, of cells simultaneously; and, advanced microscopes that allow researchers to visualize the activity of all the cells in the brains of small animals.

The study specifically targets two different types of brain cells, called microglia and astrocytes, that work to keep the immune system in check and clear out old and damaged cells, preventing disease.