Sentences with phrase «different brain diseases»

Ransohoff reminds the audience that dysfunctional microglia can cause several different brain diseases.
Richard Ransohoff (Biogen) studies a process called «inflammation» in the brain in different brain diseases.
«Now, our goal is to see how this mechanism is affected in different brain diseases and determine if it can be harnessed to protect neurons and ultimately preserve brain function.»

Not exact matches

After many setbacks, researchers have been trying different approaches to treating the neurodegenerative disease, such as starting treatment earlier and finding new ways to target the brain.
If the Sun or the Moon were a tiny bit different, perhaps we wouldn't be here; but perhaps we would be - and possibly we would be even better, with sturdier bodies, larger, more active brains, better resistance to disease, etc..
The symptoms are caused by different diseases, which affect the brain, such as Alzheimer's.
If conditions on Earth were different, we would be different — perhaps even better, though, with stronger bodies, fewer tendencies to disease and larger brains to figure out answers more easily and completely.
Since the first human brain organoids were created from stem cells in 2013, scientists have gotten them to form structures like those in the brains of fetuses, to sprout dozens of different kinds of brain cells, and to develop abnormalities like those causing neurological diseases such as Timothy syndrome.
By subdividing the brain more strategically, the map can help pinpoint particular sections» functions and help determine how different cortical regions contribute to development, aging and disease.
«The method supports detecting microRNAs directly from very small volumes of CSF to potentially get an indication of different types of diseases, including amyotrophic lateral sclerosis (ALS), Alzheimers, Huntingdon's, and traumatic brain injuries,» says Pregibon.
The behavioral tests used here modeled one dimension of the disease — an inability to experience pleasure from normal activities — but not others, such as stress and anxiety, and probably tap into different brain mechanisms in mice than in humans, he says.
As for the Lund researchers, the method provides a tool for studying how neurons cooperate inside a healthy brain and in animal models with different neurological diseases.
Raising further doubt, a team led by Douglas Galasko, director of the Alzheimer's Disease Research Center at the University of California, San Diego, twice tried to find BMAA in Chamorros and North Americans who died of brain disease — and both times came up empty - handed, though using a different method of chemical identification than the one employed by Cox and the MiamDisease Research Center at the University of California, San Diego, twice tried to find BMAA in Chamorros and North Americans who died of brain disease — and both times came up empty - handed, though using a different method of chemical identification than the one employed by Cox and the Miamdisease — and both times came up empty - handed, though using a different method of chemical identification than the one employed by Cox and the Miami team.
Neurodegenerative diseases are caused by the death of neurons and other cells in the brain, with different diseases affecting different regions of the brain.
Two kinds of mouse glial brain cells, microglia and astrocytes, making different versions of the APOE protein were grown with brain nerve cells, or neurons, that make disease - causing forms of tau.
To demonstrate the chip's efficacy in modeling disease, the team doped different regions of the brain with the drug Phencyclidine hydrochloride — commonly known as PCP — which simulates schizophrenia.
«This shows how important it is to implement different brain regions into in vitro models, especially when studying how neurological diseases impact connected regions of the brain
Brains of patients with Alzheimer's disease clog up too, but with plaques made from a different protein called amyloid beta peptide.
By comparing doctor's reports of a patient's symptoms with images of the patient's brain post-mortem, they may be able to classify different categories of Alzheimer's disease.
A molecule that helps cells stick together is significantly over-produced in two very different diseases — rheumatoid arthritis and a variety of cancers, including breast and brain tumors, concludes a new study.
The brain of a female migraineur looks so unlike the brain of a male migraineur, asserts Harvard scientist Nasim Maleki, that we should think of migraines in men and women as «different diseases altogether.»
They focused on three different types of PVD: arterial disease in the lower extremities, called peripheral artery disease; carotid artery stenosis, which is blockage in the carotid arteries, the major blood vessels in the neck that supply blood to the brain, neck and face; and abdominal aortic aneurysm, an enlargement of the lower aorta, the major blood vessel that supplies blood to the body.
A report published in The Lancet Neurology evaluates for the first time how well different types of brain imaging tests work to detect Alzheimer's and predict how the disease will progress.
BRAIN MAZE Even before symptoms show up, young people who have a version of a gene linked to Alzheimer's disease tap into different areas of the brain to navigate through a virtual reality BRAIN MAZE Even before symptoms show up, young people who have a version of a gene linked to Alzheimer's disease tap into different areas of the brain to navigate through a virtual reality brain to navigate through a virtual reality maze.
«New possibility of studying how Alzheimer's disease affects the brain at different ages.»
That variety cropped up in a different part of the brain than the other strains, and it also produced clumps of proteins akin to the amyloid plaques found in sporadic Creutzfeldt - Jakob disease, a fatal brain disease of unknown origin that usually affects those over age 55.
Brain cells from different people vary in their susceptibility to Zika infections, says infectious disease researcher Scott Weaver, also at the University of Texas Medical Branch but not involved in the study.
Damage to the olfactory receptor neurons because of a respiratory infection, a head injury or a neurodegenerative disease can disrupt the brain's ability to process different smells.
This could, for example, be a normal brain and a diseased brain, or the same brain at two different stages of development.
Our investigations also open a new route for understanding how different physiological states of the body influence stem cells in the brain during health and disease, and opens new ways for thinking about therapy,» says Fiona Doetsch.
This is very different from the idea dominant in psychiatry, that mental illness is a brain disease.
Each form of Alzheimer's disease should perturb different brain networks and so influence the concentration of different proteins that can be measured in the blood.
«Although different types of brain stimulation are currently applied in different locations, we found that the targets used to treat the same disease are nodes in the same connected brain network,» says first author Michael D. Fox, MD, PhD, an investigator in the Berenson - Allen Center for Noninvasive Brain Stimulation and in the Parkinson's Disease and Movement Disorders Center at Bbrain stimulation are currently applied in different locations, we found that the targets used to treat the same disease are nodes in the same connected brain network,» says first author Michael D. Fox, MD, PhD, an investigator in the Berenson - Allen Center for Noninvasive Brain Stimulation and in the Parkinson's Disease and Movement Disorders Center atdisease are nodes in the same connected brain network,» says first author Michael D. Fox, MD, PhD, an investigator in the Berenson - Allen Center for Noninvasive Brain Stimulation and in the Parkinson's Disease and Movement Disorders Center at Bbrain network,» says first author Michael D. Fox, MD, PhD, an investigator in the Berenson - Allen Center for Noninvasive Brain Stimulation and in the Parkinson's Disease and Movement Disorders Center at BBrain Stimulation and in the Parkinson's Disease and Movement Disorders Center atDisease and Movement Disorders Center at BIDMC.
It binds to the beta - amyloid plaques that characterize Alzheimer's disease, helping to measure the extent to which plaques have formed in different brain regions.
For the last decade, neuroscientists have been using the non-invasive brain - mapping technique functional called magnetic resonance imaging or fMRI to examine activity patterns in human and animal brains in the resting state in order to figure out how different parts of the brain are connected and to identify the changes that occur in neurological and psychiatric diseases.
«As we're trying different types of brain stimulation for different diseases, the question comes up, «How does one relate to the other?
The mutations take place on a protein that serves as the precursor for amyloid beta, a different protein that forms plaques in the brains of individuals afflicted by Alzheimer's disease.
New York, NY (February 1, 2012)-- For decades, researchers have debated whether Alzheimer's disease starts independently in vulnerable brain regions at different times, or if it begins in one region and then spreads to neuroanatomically connected areas.
One is about understanding how the function of the brain circuitry is altered by different movement - related disease processes, such as stroke and Parkinson's disease.
It isn't too different from how electroshock therapy works to counter certain mental illnesses and how deep - brain stimulation smooths motion disorders such as multiple sclerosis and Parkinson's disease.
This unique pattern of brain cell death causes different symptoms in each disease.
By directly altering the gene coding for the prion protein (PrP), Whitehead Institute researchers have created mouse models of two neurodegenerative prion diseases, each of which manifests in different regions of the brain.
The mass die - off of nerve cells in the brains of people with Alzheimer's disease may largely occur because an entirely different class of brain cells, called microglia, begin to fall down on the job, according to a new study by researchers at the Stanford University School of Medicine.
The Group studies how transporter proteins (in normal and diseased brains of different ages) modulate the extracellular spatiotemporal concentration profiles of excitatory (glutamate and aspartate) and inhibitory (GABA and glycine) transmitter amino acids.
In addition to explaining how different diseases affect the brain, Jin's research might point the way for new therapies for these disorders.
In collaboration with the University of California, Davis, D'Azzo and her colleagues have begun checking NEU1 levels in brain tissue of Alzheimer's patients at different stages of the disease.
In this work, we transplanted hematopoietic stem and progenitor cells into the substantia nigra of brains of two different mouse models of Parkinson's disease.
«We've learned a lot about the brain from mice, but I think we can all agree that mice and humans are very different,» says Li - Huei Tsai, a neuroscientist at the Picower Institute for Memory and Learning at MIT who studies the neurobiology of Alzheimer's disease.
Extensive damage to white matter (myelin - rich brain areas) characterizes Alzheimer's disease, Huntington's disease, and Parkinson's disease, pointing to myelin damage and oligodendrocyte impairment as a common path to the progression of these diseases, even though each of these diseases may have a different cause.
The benefits of using olfactory receptor neuron samples to study psychiatric disorders and patient responsiveness include their similarity to brain neurons, the relatively easy biopsy procedure, and the potential for scientists to sample and compare cells from the same patients throughout several different stages of disease.
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