Sentences with phrase «different breast cancer»

The effect of a novel antagonist of growth hormone releasing hormone on cell proliferation and on the key cell signaling pathways in nine different breast cancer cell lines.

The researchers then compared tumor cells isolated from multiple different breast cancer patients and found that cells expressing lower amounts of Numb - 1 and -2 were more resistant to the chemotherapy agent cisplatin.

The researchers have isolated the sesquiterpene lactone damsin from the plant and studied its effect on cancer stem cells in three different breast cancer cell lines.

Not exact matches

When three researchers asked 12 breast cancer patients from central Mexico, for instance, what each did right after discovering a lump in her breast, the women's answers revealed a dozen different health care routes — paths that led, in some cases, to markedly different outcomes.

Breast milk has been discovered to have cancer - killing properties against many different types of cancer, in a petri dish and in the human body.

Each of us with breast cancer (and I include men) has a different set of genes, personal backgrounds and lifestyles.

Cancerous lumps include the different types of breast cancer.

The breasts of a woman who has gone through breast cancer are much different than those who haven't had to.

Listening to the individual's experience Everyone's experience of breast cancer is different and the medical treatments required will vary.

There are over 200 different types of cancer that can occur anywhere in the body; the most frequently occurring are lung, breast and bowel cancer.

Human breast cancers can be classified according to their histological and molecular features into different subtypes, including luminal, ERBB2 and basal - like tumors.

Bernard Friedenson, associate professor of biochemistry and molecular genetics at UIC, looked at the DNA sequences of breast cancers from 21 different women and found mutations in genes involved in immunity in every one of them.

The study has been tested in metastatic patients with different primary tumours such as breast, colon and lung cancer.

The mutations were different in each of the breast cancers he analyzed, but all the mutations would have affected some aspect of pathogen recognition and defense, especially against viruses, Friedenson said.

Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.

In the future, this model will be used to assess whether the clinical heterogeneity observed in breast cancers arises from their different cancer cell of origin.

In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.

Colon cancer requires different drug regimens than lung, breast, or skin cancer.

Professor Nigel Bundred, from The University of Manchester and University Hospital of South Manchester NHS Foundation Trust, who led the study, said: «We know that different subtypes of invasive breast cancer have different levels of disease recurrence.

«What's so cool is the same drug that stops breast cancer cells from undergoing coalescence also stops melanoma cells from undergoing coalescence, despite these cancers» whole history being different,» Soll says.

The large size and diverse racial / ethnic makeup of the Breast Cancer Family Registry allowed the researchers to evaluate mortality risk across different subtypes of breast cancer and subgroups of patients, and adjust for confounding faBreast Cancer Family Registry allowed the researchers to evaluate mortality risk across different subtypes of breast cancer and subgroups of patients, and adjust for confounding faCancer Family Registry allowed the researchers to evaluate mortality risk across different subtypes of breast cancer and subgroups of patients, and adjust for confounding fabreast cancer and subgroups of patients, and adjust for confounding facancer and subgroups of patients, and adjust for confounding factors.

Pre-clinical studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from human breast cancer patient biopsies.

The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.

The authors note that prior studies have reported elevated levels of distress among people with cancer, but they vary in quality due to small sample sizes, different diagnostic criteria and assessment standards, and an over-representation of women with breast cancer.

She has described the impact that different estrogen receptors have on breast, pancreatic, and colorectal cancer, including transcriptomic effects involving long noncoding RNAs and microRNAs.

The participants had various different types of cancer, and Hirotsu says the worms successfully identified cancer in all nine they were exposed to — stomach, colorectal, colon, oesophageal, pancreas, bile duct, prostate, breast and lung cancer.

Analysis of blood samples taken at several points in time from a group of patients with different forms of advanced metastatic breast cancer found CTC clusters in the blood of 35 percent of patients and that the survival of those with more clusters in their blood was significantly reduced.

«Our data confirmed that, while the rate of growth of triple - negative breast cancer was not affected by CDK 4/6 inhibitors, this class of drugs was able to significantly inhibit the spread of triple - negative breast cancer to distant organs when tested in multiple different triple - negative breast cancer models, including patient - derived xenografts.»

Navin's team developed a new sequencing approach called Nuc - Seq, revealing that different subtypes of breast cancer displayed varied tumor diversity.

«When it spreads, breast cancer often does not spread as a single cell, but rather as a collection of cells that may have different genes driving them,» Siegel said.

A given gene may perform a different function in breast cancer cells than in healthy cells due to changes in networks of interacting proteins, according to a new study published in PLOS Computational Biology.

An analysis of mutations in the BRCA1 and BRCA2 genes reveals that women with breast cancer and women with ovarian cancer harbored mutations in different regions of the genes.

A molecule that helps cells stick together is significantly over-produced in two very different diseases — rheumatoid arthritis and a variety of cancers, including breast and brain tumors, concludes a new study.

Hardy went to GS6 looking for possible international collaborators to continue her studies of breast cancer across different populations.

The researchers then exposed cells from each of these lines to a panel of 31 different drug treatments — including 23 chemotherapy compounds approved by the FDA for breast and ovarian cancers, six targeted cancer drugs, and two common drug combinations.

By producing the metabolite 2 - phosphoglycerate, PGAM1 regulates several different metabolic pathways, and the levels of this enzyme are abnormally elevated in various human cancers, including breast cancer, lung cancer, and prostate cancer.

The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple human cancer cell lines to different chemotherapy agents based on the cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor cells to common classes of chemotherapy treatment.

New Scientist spoke to breast cancer specialist Allison Kurian, of Stanford University in California who has developed a tool that enables women to determine how different treatment options can reduce their overall risk.

For the study, Dr. Hodgson's research team gathered published information from dozens of studies about the risk of developing breast cancer in childhood lymphoma survivors, the accuracy of different forms of breast cancer screening, and the rates at which women agree to be screened when asked.

The Nature Communications paper covers lung cancer cells; a similar phenomenon of collective invasion led by distinctive cells has been observed in breast cancer, but different genes and biochemical pathways appear to be important in each system.

Using all the existing data that was available, Andrechek, along with MSU doctoral student Daniel Hollern, analyzed 1,172 mouse mammary tumor samples from 26 different preclinical models and was able to compile one of the largest databases to show which strains of mice were best suited to study a particular type of human breast cancer.

In collaboration with Dr Gabriele Bonatz from the Augusta clinics in Bochum (Brustzentrum), Hatt's team confirmed the existence of TRPV1 in tumour cells in nine different samples from patients suffering from breast cancer.

Geneticists have so far concentrated on genes that are linked to disease: first the simple but rare inherited diseases like cystic fibrosis (the gene for which is on chromosome 7) or Huntington's (chromosome 4), then the environmental diseases for which different people inherit different susceptibilities, such as Alzheimer's (chromosome 19) or breast cancer (chromosomes 13 and 17).

The analysis also found that the chance of pregnancy was reduced in all age groups, with substantial variations between different cancer diagnoses — notably, reduced pregnancy rates in women with cervical cancer, breast cancer and leukemia.

«There is growing evidence that breast cancer consists of different subtypes of cells including non-cancer stem cells and cancer stem cells,» said Ince, who is also associate professor of pathology at the University of Miami Miller School of Medicine.

Different types of tumors show a preference for specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.

Dr. David Gilley's laboratory at the Indiana University School of Medicine in Indianapolis and Dr. Connie Eaves» laboratory at the BC Cancer Agency's Terry Fox Laboratory in Vancouver, Canada, collaborated to determine how telomeres are regulated in different types of normal breast cells.

«To evaluate these findings in a group with only one HER2 treatment, we are currently analyzing data from another clinical trial, the GeparQuinto clinical trial, which is a randomized, phase III clinical trial evaluating two different neoadjuvant therapy regimens with a single anti-HER2 treatment [trastuzumab or lapatinib] for women with HER2 - positive breast cancer,» said Loibl.

The Arf6 pathway may also boost the drug resistance of breast cancer cells, and Hashimoto et al. found that inhibiting Rab11b, or a component of the Arf6 pathway called EPB41L5, increased the sensitivity of MDA - MB - 231 cells to two different cytotoxic compounds.

«This was unexpected and suggests fundamental but unrecognized differences in drug action in tumor cells from different individuals having the same disease — in this case, breast cancer.»