The effect of a novel antagonist of growth hormone releasing hormone on cell proliferation and on the key cell signaling pathways in nine
different breast cancer cell lines.
The researchers have isolated the sesquiterpene lactone damsin from the plant and studied its effect on cancer stem cells in three
different breast cancer cell lines.
Not exact matches
The researchers then exposed
cells from each of these
lines to a panel of 31
different drug treatments — including 23 chemotherapy compounds approved by the FDA for
breast and ovarian
cancers, six targeted
cancer drugs, and two common drug combinations.
The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple human
cancer cell lines to
different chemotherapy agents based on the
cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of
breast and ovarian tumor
cells to common classes of chemotherapy treatment.
To directly evaluate the relationship between ABL family kinases and metastasis, we analyzed ABL1 and ABL2 protein abundance in MDA - MB - 231 — derived
breast cancer cell lines with
different organ metastasis tropisms (19).
One study examined the cytotoxic effects of
different types of clove extract on
breast cancer cell lines, including water - based, alcohol - based and essential oil extracts.