Sentences with phrase «different cancer cell»

It's been shown to be anticancer, fights cancer in over 60 different cancer cell lines, meaning 60 different types of cancer.

Given their similar profiles, Seyedsayamdost and coworkers hypothesized that TDA might exhibit anticancer properties as well, and indeed observed its strong anticancer activity in a screen against 60 different cancer cell lines.

In the future, this model will be used to assess whether the clinical heterogeneity observed in breast cancers arises from their different cancer cell of origin.

One example is in tumor biology, where different cancer cells are likely to have different methylation patterns.

Because the different cancer cells within a tumorous tissue also develop different modes of defense against therapeutic measures, the treatment of patients is extraordinarily difficult.

Professor Scheffler provides a comparison for the procedure: «Like a car that is disassembled into its individual parts to check for damage, we examine the different cancer cells.»

Different cancer cells might bear any number of variations that let them escape the drug's effects.

By seeding elements with an assortment of antibodies, the device could be set up to capture several different cancer cells types using a single blood sample.

We also unraveled the role of PHD2 in different cancer cells during tumor development in mice.

Different cancer cells grow as a result of various risk factors, such as too much sun, which can cause the skin to form a melanoma or smoking addicts can risk developing cancer.

Not exact matches

This feat is possible because cancer cells emit a different kind of metabolic waste than healthy cells.

It is completely different in the most important ways, which is it does NOT feed cancer cells in the way highly processed white sugar does and it does NOT cause chemical reactions in the brain (exactly like heroin)-- keeping you craving more sugary foods / drinks like highly processed white sugar does.

«By studying the ways different proteins like keratin dynamically change within a cell, we can better understand the progression of cancers and other diseases,» they say.

In one respect the first look is unnerving, because the chemical mechanisms that seem to drive the cancer cell astray are not different in kind from mechanisms at work in the normal cell.

Seeking one mechanism to explain the induction of cancer by many different agents, Huebner and Todaro had suggested that retrovirus oncogenes are a part of the genetic baggage of all cells, perhaps acquired through viral infection early in evolution.

They looked at three different sets of lab - grown liposarcoma cells — a cancer of fat and connective tissues.

Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.

An analysis of the HPV16 genome from 5,570 human cell and tissue samples revealed that the virus actually consists of thousands of unique genomes, such that infected women living in the same region often have different HPV16 sequences and variable risks to cancer.

What's more, the highly connected «hub» miRNAs were often different for cancer cells (Genome Research, DOI: 10.1101 / gr.098046.109).

Other CAR - T cells that were tuned to different molecular targets also did not kill the DIPG cancer cells.

Metastasis, the process that allows some cancer cells to break off from their tumor of origin and take root in a different tissue, is the most common reason people die from cancer.

However, for patients with lymphoma, it may be a rather different story, as new research from the University of Copenhagen shows that toxins in the staphylococcus bacteria help cancer cells gain control over healthy cells.

Schwarz and her colleagues used three different drugs, alone and in combination, to deprive cervical tumors of glucose and block downstream metabolic pathways that help protect cancer cells from building up toxic free radicals.

Chinnaiyan and colleagues then conducted studies using cancer cells and found that the different FGFR fusion proteins all seemed to drive cancer cell proliferation by activating FGFR signaling.

What if proliferation is the norm for cells — and a very different theory of cancers» cause is waiting in the wings?

The researchers tested the drug combinations against four different human cervical cancer cell lines.

In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.

Cancer stem cells will need to be identified and treated in a different manner than the bulk tumor.»

«Different types of cancer cells with different strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more effDifferent types of cancer cells with different strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more effdifferent strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more efficiently.

The researchers then used a combination of existing United States Food and Drug Administration - approved drugs to target autophagy and found ovarian cancer cells to be highly sensitive to these drugs in several different mouse cancer models — even among cells resistant to standard chemotherapy.

«What's so cool is the same drug that stops breast cancer cells from undergoing coalescence also stops melanoma cells from undergoing coalescence, despite these cancers» whole history being different,» Soll says.

Pre-clinical studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from human breast cancer patient biopsies.

«Recent studies suggest that epigenetic modifications may contribute to the development of cancer progenitor cells that can induce drug resistance and the relapse of different types of cancer,» said Sibaji Sarkar, PhD, instructor of medicine at BUSM.

Cancer cells may produce unique metabolic profiles, in part because they grow very rapidly and have metabolic activity very different from normal cells.

The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.

«This could be useful in developing new combination therapies, where multiple drugs are used simultaneously to treat a cancer by attacking different parts of the cancer cells at the same time.»

Research based on such false cell lines would undermine the understanding of different cancers and possible treatments, and clutter the scientific literature with bogus conclusions.

What if proliferation is the norm for cells — and a very different theory of cancers» cause is waiting in the wings, ask Carlos Sonnenschein and Ana M. Soto

Plotting the total number of stem cell divisions over a lifetime against the lifetime risk of cancer in 31 different organs revealed a correlation.

Using tumor samples from a patient, they do lab tests to determine which substances can first make the different types of cancer cells uniform and then effectively kill them.

PTEN prevents tumor cells from growing uncontrollably, and mutations in the gene encoding this protein are commonly found in many different types of cancer.

For each patient, the suitable combination treatment could then be designed, which, in the first step, would turn the variety of different tumor cells into a mass of cancer cells of the same type.

«We're a very broad church, requiring many different areas of expertise,» says Fiona Watt, with the Cancer Research UK Cambridge Research Institute and the 2008 - 2009 president of the International Society for Stem Cell Research (ISSCR).

In a related study, published online on March 27 in the same journal, Green's group also showed that a different particle formulation could effectively carry and deliver so - called siRNAs to brain cancer cells.

From tissue and cell samples from five glioblastoma patients, the scientists obtained 33 individual cancer cells capable of reproduction, which grew into very different tumors in the lab.

Backman has been studying cell abnormalities at the nanoscale in many different types of cancers, using an optical technique he pioneered called partial wave spectroscopic (PWS) microscopy.

Slusher teamed up with Johns Hopkins Kimmel Cancer Center immunologist Jonathan Powell, M.D., Ph.D., who has studied how cancer cells use different metabolic pathways to evade destruction by immune Cancer Center immunologist Jonathan Powell, M.D., Ph.D., who has studied how cancer cells use different metabolic pathways to evade destruction by immune cancer cells use different metabolic pathways to evade destruction by immune cells.

If metastatic cancers are most often made up of cells with different genetic drivers, perhaps researchers should be targeting the primary tumor with multiple drugs to contain the cancer.

The device has been used to separate different blood components, to separate cancer cells from blood and to manipulate nanorod motors inside living cells, to name only a few research areas.

«Same cancer, different time zone: Cancer cells each grow at different speeds, study shows.&cancer, different time zone: Cancer cells each grow at different speeds, study shows.&Cancer cells each grow at different speeds, study shows.»