The follow up Biosensors paper, provides a proof - of - principle use of these probes as tools to assess and compare GLUT5 and metabolic activity of different cell types, including normal cells and
different cancer subtypes.
Not exact matches
Human breast
cancers can be classified according to their histological and molecular features into
different subtypes, including luminal, ERBB2 and basal - like tumors.
Professor Nigel Bundred, from The University of Manchester and University Hospital of South Manchester NHS Foundation Trust, who led the study, said: «We know that
different subtypes of invasive breast
cancer have
different levels of disease recurrence.
The large size and diverse racial / ethnic makeup of the Breast
Cancer Family Registry allowed the researchers to evaluate mortality risk across different subtypes of breast cancer and subgroups of patients, and adjust for confounding fa
Cancer Family Registry allowed the researchers to evaluate mortality risk across
different subtypes of breast
cancer and subgroups of patients, and adjust for confounding fa
cancer and subgroups of patients, and adjust for confounding factors.
Then we can look for
different treatment options, guided either by a mutation unique to that person's
cancer or perhaps unique to that
subtype of tumor.
Navin's team developed a new sequencing approach called Nuc - Seq, revealing that
different subtypes of breast
cancer displayed varied tumor diversity.
In other disease areas, the Parkinson's disease map and the Atlas of
Cancer Signalling Network, have already begun the process of integrating knowledge about the involved mechanisms in order to understand the
different subtypes of these diseases.
«There is growing evidence that breast
cancer consists of
different subtypes of cells including non-
cancer stem cells and
cancer stem cells,» said Ince, who is also associate professor of pathology at the University of Miami Miller School of Medicine.
This finding suggests that patients with this
subtype may respond better to alternative treatments that target their tumors» unique genetic structure, which is
different than most cervical
cancers.
The ability to specifically target
different integrin
subtypes is an important step toward personalized medicine in which all kinds of
cancer can be fought on a patient - specific basis.
Different subtypes in the same
cancer behave differently, and that raises challenges for those of us who are seeking new treatments and for personalised treatment approaches.
They have demonstrated that what might be popularly thought of as a single disease — say, breast
cancer — is in fact several
different subtypes characterized by long lists of mostly
different mutated genes.
Such integrated approaches are used to investigate whether
different subtypes or stages of a
cancer can be distinguished, whether a
cancer has the potential to spread, and whether a given therapy will be successful.
As with
cancers and infectious illnesses, mental illnesses once lumped together as a single disorder are beginning to be understood as multiple illnesses or
subtypes that may stem from
different causes and require
different treatments.
Although myofibroblasts expressing CXCL12 are associated with the presence of axillary metastases in HER2 breast
cancers (BC), the therapeutic interest of targeting CXCR4 / CXCL12 axis in the
different BC
subtypes remains unclear.
A network of transcription factors may drive
different subtypes of aggressive bladder
cancer, allowing researchers to turn one type of tumor into another
16) Lockwood WW †, Wilson IM, Coe BP, Chari R, Pikor LA, Thu KL, Solis LM, Nunez MI, Behrens C, Yee J, English J, Murray N, Tsao MS, Minna J, Gazdar AF, Wistuba II, MacAulay CE, Lam S, Lam WL (2012) Divergent genomic and epigenomic landscapes of lung
cancer subtypes underscore the selection of
different oncogenic pathways during tumor development.
Dr. Carey is a nationally - recognized leader in the field of clinical / translational research in breast
cancer, with a particular interest in the clinical implications of
different molecular
subtypes of breast
cancer.
There are many
different subtypes of NHL, and they often show up in the form of an enlarged lymph node — although lymphomas can also start in other lymphatic tissue in the spleen, bone marrow, tonsils, or digestive tract, among other places, according to the American
Cancer Society (ACS).
There are also
different subtypes of the
cancer itself, referring to the type of
cancer cells rather than where they are found.