Sentences with phrase «different cancers use»

Dr Madhu Basetti, co-lead researcher also based at the Cancer Research UK Cambridge Institute, said: «Our study is the first to use this approach to compare how different cancers use and produce energy, and look for similarities.

The fact that prostate cancer grew independently of the presence of SLC13A5 supports the idea that different cancers use different methods to meet their high energy requirements.

Not exact matches

Discover what AI solutions are being used currently in hospitals, clinics, and health networks, and how they're improving operations in vastly different corners of the industry, from increasing efficiency in EMRs and data - mining all the way to providing life - saving cancer diagnoses.

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In the future, this model will be used to assess whether the clinical heterogeneity observed in breast cancers arises from their different cancer cell of origin.

Schwarz and her colleagues used three different drugs, alone and in combination, to deprive cervical tumors of glucose and block downstream metabolic pathways that help protect cancer cells from building up toxic free radicals.

Chinnaiyan and colleagues then conducted studies using cancer cells and found that the different FGFR fusion proteins all seemed to drive cancer cell proliferation by activating FGFR signaling.

The researchers then used a combination of existing United States Food and Drug Administration - approved drugs to target autophagy and found ovarian cancer cells to be highly sensitive to these drugs in several different mouse cancer models — even among cells resistant to standard chemotherapy.

«We can use different approaches to reverse methylation,» she says, «turning silenced genes back on, and seeing whether we can prevent the tumours from occurring or treat the cancer after it has appeared.»

Different types of studies use different stand - ins: Flies for genetics; zebrafish for early development; rats and mice and monkeys for cancer, neuroscience Different types of studies use different stand - ins: Flies for genetics; zebrafish for early development; rats and mice and monkeys for cancer, neuroscience different stand - ins: Flies for genetics; zebrafish for early development; rats and mice and monkeys for cancer, neuroscience and more.

«This could be useful in developing new combination therapies, where multiple drugs are used simultaneously to treat a cancer by attacking different parts of the cancer cells at the same time.»

A second study, out of MIT, used principles of computer engineering to design a molecular logic circuit that senses six different biomarkers, seeking out a chemical pattern unique to one type of cancer.

Use of this knowledge to screen several different drugs, or combinations of drugs, is emerging as an important approach to cancer treatment.

Using tumor samples from a patient, they do lab tests to determine which substances can first make the different types of cancer cells uniform and then effectively kill them.

«The phi test helps physicians distinguish prostate cancer from benign conditions by utilizing three different PSA markers (PSA, freePSA and p2PSA) as part of a sophisticated algorithm to more reliably determine the probability of cancer in patients with elevated PSA levels,» said Kevin Slawin, MD, director, Vanguard Urologic Institute at Memorial Hermann Medical Group, clinical professor of Urology at Baylor College of Medicine and director of Urology, Memorial Hermann Hospital ‐ Texas Medical Center, who performed some of the key research that led to the development of the phi test and who also began using the test in February.

Backman has been studying cell abnormalities at the nanoscale in many different types of cancers, using an optical technique he pioneered called partial wave spectroscopic (PWS) microscopy.

«This strategy can potentially be used to develop tailored drugs for different cancers.»

Slusher teamed up with Johns Hopkins Kimmel Cancer Center immunologist Jonathan Powell, M.D., Ph.D., who has studied how cancer cells use different metabolic pathways to evade destruction by immune Cancer Center immunologist Jonathan Powell, M.D., Ph.D., who has studied how cancer cells use different metabolic pathways to evade destruction by immune cancer cells use different metabolic pathways to evade destruction by immune cells.

The device has been used to separate different blood components, to separate cancer cells from blood and to manipulate nanorod motors inside living cells, to name only a few research areas.

To understand this spread, the Penn researchers developed a mouse model that uses multiple fluorescent proteins to tag and track different pancreatic cancer cells as they enter the bloodstream and spread to distant organs.

The authors showed that the use of this drug remains widespread in Asia and particularly in Taiwan, and that it appears to increase the risk of multiple different cancer types.

The team used five types of antibiotics — including one used to treat acne (doxycycline)-- on cell lines of eight different types of tumour and found that four of them eradicated the cancer stem cells in every test.

Prof Tony Green, an author from the Wellcome Trust - MRC Stem Cell Institute and Cambridge University, said: «The SC3 tool was able to use patterns of gene expression to distinguish, within an individual cancer, subclones that carried different mutations.

In this way our study took a very different approach as we have used chemistry to mimic genetic mechanisms that are able to block the development of Ras - dependent cancers.»

A different pathway is used to train students in the combined degree program at the University of Texas Health Science Center at Houston (UT Houston) and the University of Texas M. D. Anderson Cancer Center, where the goal is to produce physician - scientists who will pursue careers in clinical research.

«Although right now we are focusing on developing a cancer vaccine, in the future we could be able to manipulate which type of dendritic cells or other types of immune cells are recruited to the 3D scaffold by using different kinds of cytokines released from the MSRs,» said co-lead author Aileen Li, a graduate student pursuing her Ph.D. in bioengineering at Harvard SEAS.

The study used a well - known line of pancreatic cancer cells (AsPC - 1) in the laboratory and assessed how well this grew when treated with either the chemotherapy drug gemcitabine or different levels of commercially available chokeberry extract alone, and when treated with a combination of gemcitabine and chokeberry extract.

A similar principle is used in the medical field to detect biomarkers for different kinds of health conditions, including cancer, by taking breath samples.

Using all the existing data that was available, Andrechek, along with MSU doctoral student Daniel Hollern, analyzed 1,172 mouse mammary tumor samples from 26 different preclinical models and was able to compile one of the largest databases to show which strains of mice were best suited to study a particular type of human breast cancer.

Their recent study, which appears as the cover article in the May issue of Cancer Research, shows that mathematical models can be used to predict how different tumor cell populations interact with each other and respond to a changing environment.

While the 3D injectable scaffold is being tested in mice as a potential cancer vaccine, any combination of different antigens and drugs could be loaded into the scaffold, meaning it could also be used to treat infectious diseases that may be resistant to conventional treatments.

Another example is radiotherapy, used in the treatment of different cancers.

The follow up Biosensors paper, provides a proof - of - principle use of these probes as tools to assess and compare GLUT5 and metabolic activity of different cell types, including normal cells and different cancer subtypes.

Christian Seiser says: «Our results highlight that it is crucial to understand the individual role the various HDAC variants in different cell types and hence different types of cancer, before HDAC inhibitors can be used safely as therapeutics.»

This strategy could eventually help the researchers to determine which peptides to use for different types of cancer, and even for individual patients.

«These molecules» existence can also be used to classify cancer patients into subgroups of individuals with different survival outcomes,» adds Jones.

Although most of the work has been carried out using in vivo studies, Asst Prof Gasser has been collaborating with Dr Joanne Ngeow at the National Cancer Centre Singapore to characterise the process in different types of human tumours.

Through the study, researchers were also able to pinpoint three different brain changes caused by the progression of cancer and the drugs used in treatment.

To investigate why checkpoint inhibitors so often stop working, Velculescu; Valsamo Anagnostou, M.D., Ph.D., instructor of oncology at the Johns Hopkins University School of Medicine; Kellie N. Smith, Ph.D., a cancer immunology research associate at the Johns Hopkins University School of Medicine; and their colleagues at the Bloomberg ~ Kimmel Institute for Cancer Immunotherapy studied tumors of four patients with non-small cell lung cancer and one patient with head and neck cancer who developed resistance to two different checkpoint inhibitors: a drug called nivolumab that uses an antibody called anti-PD-1, or nivolumab used alone or in combination with a second drug called ipilimumab, which uses an antibody called anti-cancer immunology research associate at the Johns Hopkins University School of Medicine; and their colleagues at the Bloomberg ~ Kimmel Institute for Cancer Immunotherapy studied tumors of four patients with non-small cell lung cancer and one patient with head and neck cancer who developed resistance to two different checkpoint inhibitors: a drug called nivolumab that uses an antibody called anti-PD-1, or nivolumab used alone or in combination with a second drug called ipilimumab, which uses an antibody called anti-Cancer Immunotherapy studied tumors of four patients with non-small cell lung cancer and one patient with head and neck cancer who developed resistance to two different checkpoint inhibitors: a drug called nivolumab that uses an antibody called anti-PD-1, or nivolumab used alone or in combination with a second drug called ipilimumab, which uses an antibody called anti-cancer and one patient with head and neck cancer who developed resistance to two different checkpoint inhibitors: a drug called nivolumab that uses an antibody called anti-PD-1, or nivolumab used alone or in combination with a second drug called ipilimumab, which uses an antibody called anti-cancer who developed resistance to two different checkpoint inhibitors: a drug called nivolumab that uses an antibody called anti-PD-1, or nivolumab used alone or in combination with a second drug called ipilimumab, which uses an antibody called anti-CTLA4.

I have a chapter in my book Cancer Wars called «Doubt Is Our Product,» which is about the hundreds and hundreds of different industries that use these techniques of sowing doubt in order to minimize hazard, as do various trade associations.

By seeding elements with an assortment of antibodies, the device could be set up to capture several different cancer cells types using a single blood sample.

The CNIC research team generated cytotoxic memory T cells specifically targeting cancer by using different methods for vaccination with tumor antigens.

It also may have helped several others by boosting the power of a new type of cancer drug that uses a different mechanism to unleash an immune attack on the tumor.

Using a novel approach, scientists at the International Agency for Research on Cancer (IARC - WHO) showed that three different measurements of body size, BMI, waist circumference, and waist to hip ratio all predicted similar obesity - related cancer risk in older aCancer (IARC - WHO) showed that three different measurements of body size, BMI, waist circumference, and waist to hip ratio all predicted similar obesity - related cancer risk in older acancer risk in older adults.

Researchers from the Shanghai Cancer Institute and the US National Cancer Institute in Bethesda, Maryland, examined the volatile organic compounds given off by different oils at the high temperatures typically used for wok cooking.

Christofk studies the genes and proteins behind the way cancer cells use sugars to live and grow, which is different from how normal cells do.

To illustrate potential mutation - specific effects on absolute cancer risks, we used the hazard ratio estimates to derive approximate absolute risks and 95 % confidence intervals, based on published estimates for the overall risks of breast and ovarian cancer by age 70 years.26 These estimates are for illustration and do not represent absolute risk estimates that would be required in a genetic counseling setting, as they do not account for noncancer outcomes that may influence a woman's life expectancy, the effects of family history, and nonrandom ascertainment of mutation carriers in this sample and depend on assumptions about the prevalence of different mutation classes in the population.

This approach could be used to study nearly any gene in many different types of cancer, the researchers say.

Now we want to extend this technology to animal models, such as cancer bearing mice, to verify its practical use in different types of tumors,» explains Park.

The decade - old Biorepository at the Georgia Cancer Center also has a wide array of samples from different types of cancer that are used for diagnosis and research purCancer Center also has a wide array of samples from different types of cancer that are used for diagnosis and research purcancer that are used for diagnosis and research purposes.