Concurrently, the research group is examining how the epigenetic profile of
different candidate genes predicts, and perhaps changes, in response to recovery from PTSD (and negative self - cognitions) along with its neural correlates.
Not exact matches
Then, they estimated enrichment factors by determining how frequently those known cancer - associated
genes occurred among the top
gene candidates identified by
different analysis methods.
«Humans also suffer from
different types of inherited chondrodysplasia, and the ITGA10
gene could represent a good
candidate gene for some of these disorders, which still have an unknown genetic cause,» tells Kaisa Kyöstilä, the first author of the paper.
His team performed embryology experiments, molecular cloning projects, and
candidate gene studies, coming at the problem from several
different angles at once.
«There are hundreds of
candidate genes to sort through, and a single genetic variant may have
different effects even within the same family.
Gene - expression profiling of
different arms of lymphatic vasculature identifies
candidates for manipulation of cell traffic.
An example of a «
candidate gene» experiment testing whether
different diploid genotypes are associated with
different trait values, or phenotypes.
In particular, the care taken to address issues of biological plausibility and the attempts to link specific aspects of the clinical phenotype to
different genes is notable and provides a platform for examining the role of
candidate genes on adolescent substance use.