Sentences with phrase «different cell bound»

Not exact matches

In my cell biology course, we investigate the biology and chemistry of a cell surface receptor that helps induce good feelings in us when it binds to a chemical compound found in incense; this may help explain why so many different cultures and religions have independently evolved the use of incense in their ceremonies and rituals.

In such patients, a phenomenon called «antibody - dependent enhancement» (ADE) takes place, during which antibodies that were generated during the first infection bind but do not destroy the slightly different newly infecting virus, but instead facilitate its infection of immune cells.

«It's exciting to learn that these different oligomeric structures bind differently with the human lipid cells,» Stahelin said.

The RNA - binding domains of mammalian hnRNP F / H proteins probably have a similar ability to bind two different types of RNA, allowing them to regulate diverse target RNAs within the cell.

They also have varying effects if they act on different receptors — proteins in cell membranes that bind neurotransmitters and control cell responses.

The study, «Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF - TNF - RII binding in rheumatoid arthritis,» which will be published online June 6 in The Journal of Experimental Medicine, may help explain the divergent efficacies of different TNF - targeting drugs.

Secreted by certain brain cells, APOE is known to regulate cholesterol metabolism within the brain and can bind to A-beta peptides, suggesting that the different forms of the protein may affect whether and how toxic A-beta plaques form.

Dialysis patients usually have to take 3 different medications to overcome these 3 complications related to kidney disease: drugs that bind phosphorus, erythropoietin - stimulating agents (ESA) that boost blood cell production, and intravenous (IV) iron.

These cells have different factors on their surfaces which determines how «sticky» the cells are and whether they are responsible for mediating the cancer cells binding to the blood vessel walls.

MHC I & II molecules then bind the antigen and present it to different arms of the adaptive immune system, potentially mobilizing T cells, B cells and natural killer (NK) cells.

Researchers have identified a set of DNA - binding proteins in the roots of the plant Arabidopsis thaliana that work in combination to help precursor cells selectively read different parts of the same genetic script and acquire their different fates.

PARTICLE acts in three different ways to prevent expression of the MAT2A gene: 1) by winding around the MAT2A gene to create a DNA: RNA triple helix structure locking down the MAT2A gene promoter, 2) by binding the messenger RNA product of the MAT2A gene and preventing it being used for MAT2A protein synthesis and 3) transferring MAT2A messenger RNA into intracellular vesicles that are subsequently ejected from the cell.

The genes for each transcription factor were made from different bits of DNA that code for the functional parts of proteins, such as a domain that can bind to DNA and another that provides the protein with access to the cell's nucleus.

When low levels of antibodies from a previous dengue infection sense a new serotype is around, they weakly bind to the different serotype, lead it to cells with receptors for their constant regions, and the new serotype ultimately enters those cells.

Once the intruder has been bound by the BCR, the B cell is activated and, together with other immune cells, can fight off a range of different types of pathogens.

This causes the body's white blood cells to release type 1 interferon - alpha, a small cytokine protein that acts as a systemic alarm, triggering a cascade of additional immune activity as it binds with receptors in different tissues.

After all, MERS is not SARS — it binds to a different cell receptor, so the binding site is slightly different.

X-ray studies at the Department of Energy's SLAC National Accelerator Laboratory, combined with Stanford biological studies and computational analysis, revealed remarkable similarities in the structure of binding sites, which allow a given T cell to recognize many different invaders that provoke an immune response.

Researchers compared the 3 - D structures of T cells and their unique receptors bound to different peptides at SLAC's Stanford Synchrotron Research Lightsource (SSRL).

Han et al. demonstrated that in Caco2 cells, extracellular NAD + inhibited the binding of NF - kB to DNA by blocking the transcription of different genes involved in both inflammatory and aging pathways (interlukin - 6, interlukin - 1 beta, tumor necrosis factor alpha) 27.

The overall score encompass several factors: reproducibility of the antibody staining in different cell lines (and if signal strength correlates with RNA expression levels); assays for enhanced antibody validation by using antibodies binding to different epitopes on the same target protein (independent antibodies), by knockdown / knockout of the target protein (genetic methods) and by matching of the signal with a GFP - tagged protein (recombinant expression); experimental evidence for location described in literature.

This visualization shows tightly - packed DNA in a mouse cell's nucleus at different stages of development, seen here in a semi-triangular form as a mature nerve cell; in a roundish shape as a multipotent stem cell; in a more oval form as a neuronal progenitor; and as a more fragmented structure that shows how removing a specialized binding protein (HP1β knockout) affects the structure of the DNA - packing material, called heterochromatin, in a mature neuron.

We use this in vitro model of spontaneous tumorigenesis to generate a library of cell lines with 25 different de novo JAK1 - activating mutations, 6 of which are targeting two residues, Phe958 and Pro960, located in the hinge region at the periphery of the ATP - binding pocket.

In the experiments described in the paper, the MGH team confirmed that their mesothelin - targeting fusion protein binds to mesothelin on either ovarian cancer or mesothelioma cells, activates dendritic cells, and enhances the cells» processing and presentation of several different tumor antigens, inducing a number of T - cell - based immune responses.

The team obtained not simply nanoparticles that can bind to certain types of cells, but particles that look for target cells when both of two different conditions are met, or when two different molecules are present or absent.

[PRESS RELEASE 2017-05-05] A new study in Science from Karolinska Institutet maps out how different DNA - binding proteins in human cells react to certain biochemical modifications of the DNA molecule.

Importantly, the blebs only become bound to cells that are associated with the macrophages at the time of isolation since co-preparation of LN cells from congenically distinct animals did not lead to cross acquisition of macrophage - derived blebs by innate - like lymphocytes from the different LNs (Gray et al., 2012).

Inside the cells, it binds to several different «molecular targets» and changes their function (4).

Now just like there are specialized stitches in sewing, there are other types of junctions that bind the cells together for different reasons.

Stick your nose deep into an old book and inhale deeply... As it turns out, dozens of different chemicals that are emitted by paper, binding, ink, and glue... break down over time... One prominent compound results from the breakdown of lignin, a polymer found in plant cell walls, as well as paper.