For this purpose, at least 30
different cell lines derived from biopsies (HNSCC — head and neck cancer — patients) wil be collected and grown in culture to esstablish cell lines.
Not exact matches
They tried hundreds of
different recipes; eventually they discovered that if they mixed liver precursor
cells (
derived from iPS
cells) with two other types of standard human
cell lines known to be important for embryonic liver development, then the
cells would spontaneously form a 4 to 5 - millimeter 3D structure called a liver bud.
In parthenote -
derived cell lines, they found a distinctive signature: Most genes were
different on the two sets of chromosomes, but genes located close to the chromosome's center were largely identical.
The constitutive expression of these endothelial
cell adhesion molecules was very similar for most of the
lines derived from
different organs, i.e., very low expression levels of E-selectin and VCAM - 1 and more pronounced expression of ICAM - 1.
However, efforts to examine the in vitro behavior of tumor
cells with endothelial
cells from
different anatomical regions have been prohibited because, in large part, of the limited number of organ -
derived endothelial
cell lines available for study.
Enhanced hiPS - HEP
cells are available from three
different iPSC
lines derived from healthy donors.
To directly evaluate the relationship between ABL family kinases and metastasis, we analyzed ABL1 and ABL2 protein abundance in MDA - MB - 231 —
derived breast cancer
cell lines with
different organ metastasis tropisms (19).