Sentences with phrase «different cell signaling pathways»

ROS are important signaling molecules for a number of different cell signaling pathways, particularly those associated with stress - response, and we are stress - response machines.

Not exact matches

LKB1 is known to work through different pathways, primarily the mTORC1 and AMPK signaling pathways, in conventional T cells and other settings.

«Signaling pathways and gene expression profiles are very different in cells that grow in 2D and 3D cultures,» says Oksana Sirenko, a research scientist at Molecular Devices in Sunnyvale, California.

The cells of such different organisms as roundworms, flies and humans use the insulin / IGF signalling pathway.

They found that silencing the TOR signalling pathway — activated in many different types of cancer — increased ER stress in the cells.

Named after the BMP signal protein, this pathway controls the evolution of various cell types depending on the protein concentration, similar to the Wnt pathway, but in a different direction.

The SDF - 1 / CXCR4 interaction stimulates tyrosine phosphorylation of CXCR4, followed by the activation of multiple G protein - dependent signaling pathways, which may be different among cell types.

Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem cell - like subpopulations, by a host of different mechanisms which comprise inhibition of signaling pathways, of mitochondrial respiration, as well as of cellular stress responses and others.

Ionizing radiation has been shown to activate these signaling pathways in different intensities and in a cell type - dependent manner [6].

We show that subpopulations of human astrocytes, generated by activation of different signaling pathways in the same population of human glial precursor cells, have markedly different effects when transplanted into the injured spinal cord.

The effect of a novel antagonist of growth hormone releasing hormone on cell proliferation and on the key cell signaling pathways in nine different breast cancer cell lines.

For example, studies of cell signaling pathways in normal cells and cancer cells have contributed greatly to our knowledge about the disease, revealing molecular alterations that are shared among different types of cancer and pointing to possible strategies for treatment.

On a different note, coconut oil mitigates amyloid beta toxicity in cortical neurons by up - regulating signaling of cell survival pathways (Nafar, Clarke, & Mearow, 2017).