Not exact matches
Researchers are developing many
different versions of CAR - T
cell therapies, but the basic premise is the same: Doctors remove a patient's T
cells (immune system
cells that attack invaders) from a blood sample and genetically modify them to produce artificial
proteins on their
surfaces.
Previous research had shown that nicotine seems to have conflicting effects on
different types of nicotinic acetylcholine receptors,
proteins on the
surface of brain
cells that respond to nicotine and the naturally occurring neurotransmitter acetylcholine.
T
cells are thought to be able to provide protection across
different strains, says Teijaro, because the bits of influenza virus the T
cells recognize do not mutate as much as the influenza
surface proteins, the target of antibodies.
(A)
Different biomolecules on the
surface of prepared silver nanoparticles (linker not shown); (B) in
cell culture media the nanoparticle - water interface is composed of ligands and ions but also of
proteins, the so - called
protein corona.
Subsequent work identified a
different protein on the
surface of T
cells — PD - 1 — as another key regulator of T
cell response.
Because the damaged
proteins on the
surfaces of tumor
cells look very
different from healthy
cells, the immune system is alarmed, and natural killer (NK)
cells and macrophages are immediately sent to the tumor.