Not exact matches
«We have already demonstrated that these two synapses process
different types of information that in turn is likely to comprise the
cellular mechanisms for memory encoding and retrieval at these synapses» explains Hardy Hagena.
It supports proposals that use
different technologies to build up knowledge of functional
mechanisms and intracellular dynamics with atomic structure information and integrate these into an understanding of
cellular processes in the native environment and in real time.
Dr. Tarazi studies the behavioral, genetic, molecular, and
cellular mechanisms that mediate the actions of dissimilar psychotropic drugs by using animal models that mimic the core symptoms of
different neuropsychiatric diseases.
The lab focuses on clarifying the
mechanisms of brain plasticity, gene expression, and responses of
cellular elements to
different psychotropic drugs, and have identified several novel brain sites and pathways that constitute attractive targets for new drug development.
Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem cell - like subpopulations, by a host of
different mechanisms which comprise inhibition of signaling pathways, of mitochondrial respiration, as well as of
cellular stress responses and others.
The Dotiwala laboratory uses
cellular, molecular, biochemical and omics approaches, as well as sophisticated in vivo imaging, to dissect the
mechanism by which cell - based immunity (neutrophils, macrophages and killer lymphocytes) is activated in the presence of
different pathogenic bacteria, such as intra - and extracellular bacteria, fungi and protozoa.
These biochemical
mechanisms influence four
different actions, which are
cellular apoptosis, the inhibition of cell proliferation, the suppression of cytokine production and the reduction of white blood cells or leukocytes.
Therefore the group studies with sophisticated imaging technology in vitro and ex vivo: i) the molecular
mechanism driving the migration of HIV through the intestinal epithelial barrier; ii) the
cellular targets in the mucosa, in specific macrophages and DCs, to identify the possible pathways to invade the tissue and disseminate to other organs; iii) the involvement of DCs and their functional properties in mediating adaptive immune responses at mucosal level; and iv) the role of antibodies with
different effector functions in changing the pathways of the virus.
We examine the molecular and
cellular mechanisms through which androgens and estrogens, as well as the neuropeptide vasotocin, affect behavioral and brain responses to sensory cues that elicit
different types of social output, from courtship to aggression to withdrawal.
Working as a glutathione - activating agent via three
different mechanisms, Reg» Activ ® is set to impact the future of preventative and restorative health on a
cellular level.