The results of two studies, published in Science (10 November), present a new «rule - book» to estimate the risk of
different cholera strains causing an epidemic.
The cholera studies led to the scuttling of a leading vaccine candidate, a finer understanding of effective immune responses, and, ultimately, compelling evidence that
a different cholera vaccine worked.
The results of two studies, published in Science, present a new «rule - book» to estimate the risk of
different cholera strains causing an epidemic.
Not exact matches
«We don't completely understand why those species occur during
cholera infection, but that phenomenon may offer clues as to why we observe
different species of gut bacteria among humans in
different parts of the world.
He and colleagues have determined what gives
cholera bacteria their curved shape and whether it matters (a polymer protein, and it does matter; the curve makes it easier for
cholera to cause disease), how
different wavelengths of light affect movement of photosynthetic bacteria (red and green wavelengths encourage movement; blue light stops the microbes in their tracks), how bacteria coordinate cell division machinery and how photosynthetic bacteria's growth changes in light and dark.
If Poinar gets
cholera DNA from Pozzeveri, it will let him compare the Philadelphia V.
cholerae genome with one from the same time but a
different place.
Mooi and his colleagues have looked at the DNA of free - living V.
cholerae, and found that the
different strains seem to have exchanged genes on a fairly regular basis.
This allowed the researchers to uncover that
different strains of Vibrio
cholerae can be assigned
different risks for causing large outbreaks.
Blokesch's lab grew the
cholera bacterium with
different sugars (e.g. glucose, sucrose) and starch from potatoes and rice to see how each would affect the
cholera toxin genes.
But Rita Colwell of Johns Hopkins University in Baltimore, Maryland, and colleagues report this week that of faecal samples taken from 81 people in November 2010, 17 had a
different V.
cholerae that does not make the deadly toxin made by the El Tor strain.
Given similar results from studies of a
different oral
cholera vaccine in Asia, the researchers argue that «additional evaluation of the optimal dosing schedule for oral
cholera vaccines with the goal of improving long - term immunity is warranted.»
Scholars have identified seven
different waves of
cholera pandemics beginning in 1817.
but that's no
different to arguing that botulism is better than
cholera — you really don't want to be facing either.