Sentences with phrase «different gene drives»

«When it spreads, breast cancer often does not spread as a single cell, but rather as a collection of cells that may have different genes driving them,» Siegel said.

Until recently, biologists had thought that different genes drove each instance of echolocation and that the relevant proteins could change in innumerable ways to take on new functions.

Not exact matches

What drew them into this exploratory process was not a Darwinian drive to the enhanced propagation of their genes, but an entirely different mechanism.

Gene drives aren't much different, says gene drive pioneer Austin Burt, an evolutionary geneticist at Imperial College LonGene drives aren't much different, says gene drive pioneer Austin Burt, an evolutionary geneticist at Imperial College Longene drive pioneer Austin Burt, an evolutionary geneticist at Imperial College London.

The project, which will look at how genes and environment interact to drive disease in kids, is different from its predecessors, says Kenneth Mandl, a physician, biomedical informaticist, and one of the project's leaders at Children's.

Arizona State University biologist Jim Collins, who convened a group of experts to explore the potential applications for gene drive technology earlier this year, echoed Esvelt, saying, «we need different arrangements.

Blocking the function of the Ras oncogenes is considered by many scientists to be the «holy grail» of cancer therapeutics because mutations in these genes drive the growth of so many different types of cancers.

In the current study, researchers tested two different CRISPR gene drive constructs in the model fruit fly, Drosophila melanogaster, to investigate the rise of resistance.

Gene drive is so different from other technologies involving genetic modification that it requires a whole new way of thinking about how to evaluate and regulate it, says Jennifer Kuzma, a natural and social scientist at North Carolina State University (NCSU) in Raleigh who helped organize a February workshop there.

Other organizations are looking at different aspects of gene drive.

Much more research is needed on how gene drive would work under different environmental conditions or whether the selected genes would spread to other species or change in some way over time.

The method is based on the knowledge that different tumors can be driven by different subsets of cancer genes.

When committee member Jennifer Kuzma, a policy analyst at North Carolina State University in Raleigh, asked what exactly represents a «different type of risk» from existing products, several regulators invoked another nascent technology, known as gene drive.

For instance, while I was flattered to find him quote one of my own review papers (2)-- although the quote is actually a chimera drawn from two very different parts of my review — he fails to even mention the review's (and many other papers») central point: that new genes did not drive the Cambrian explosion.

They're continuing to sequence prostate tumors to learn how frequently different mutations occur, as well as studying which of the rearranged genes are actually driving cancer.

«Many different groups and the interested public will need to come together to ensure that gene drives are developed and used responsibly,» said James P. Collins, PhD, an evolutionary ecologist at Arizona State University and senior author of the Science paper.

The federal government is launching a very different kind of cancer study that will assign patients drugs based on what genes drive their tumors rather than the type.

For example, the BR biosynthesis gene, Dwarf4 (Dwf4), had opposite effects on yield in rice when driven by different promoters (Reuzeau et al., 2006; Wu et al., 2008) and the interaction of BR and GA mutants was developmentally context - dependent in maize (Best et al., 2016).

Alterations accomplished using CRISPR, which enables scientists to edit a cell's DNA with unprecedented precision, are different in one crucial respect: The process can result in «gene drive,» a naturally occurring feature of some genes that enables them to spread through a population over generations, even if they do not help survival (and thus reproduction).

«Our study also highlights that growth of normal cells and cancer cells is driven by different gene switches, suggesting that further work to find ways to control the activity of such disease - specific switches could lead to novel, highly specific approaches for therapeutic intervention», says Professor Jussi Taipale, who led the study.

This generic daisy drive system, which would harbor the Cas9 gene in the B position but lack any A elements, could be used in three different ways.

The researchers believe that many of these paired genes with different functions have driven evolution.

So, when Seat's friendly neighbourhood racing driver and former WTCC man Jordi Gene first gets behind the wheel (testing kicks off just after the Geneva Motor Show), he'll find himself in a car that's radically different to drive in comparison to the Leon TCR.