Sentences with phrase «different gene expression patterns»

The researchers also found different gene expression patterns after the flu vaccination in younger and older people.

Not exact matches

Even more striking, the gene - expression pattern in the hippocampi of THC - treated aged mice was radically different from that of untreated elderly mice.

Once the pattern of expression of these genes had been identified, Prof. Khatri and his colleagues tested it out on the remaining 900 samples from patients with different tropical diseases and from healthy people.

They found that gene expression is different at 209 sites in chronically lonely people and that many of those changes fit a pattern of elevated immune activation, inflammation, and depressed response to infection.

For Helicobacter pylori, a pathogenic bacterium that colonizes over 40 percent of the world population and is associated with gastric cancer, the team discovered that epigenetic heterogeneity can quickly emerge as a single cell divides, and different subpopulations with distinct methylation patterns have distinct gene expressions patterns.

A necklace of early stage developing wings, each labeled fluorescently to reveal a different pattern of gene expression.

Prof Tony Green, an author from the Wellcome Trust - MRC Stem Cell Institute and Cambridge University, said: «The SC3 tool was able to use patterns of gene expression to distinguish, within an individual cancer, subclones that carried different mutations.

Our work shows an exciting new way that eRNAs produce these different patterns of gene expression.

Understanding the best ways to work with RNA and the various RNA detection methods can help scientists advance our understanding of gene expression patterns and elucidate the roles of different genomic elements in cellular function and dysfunction.

In a 2015 study of 46 people, Bearden found that people with 22q11.2 deletion syndrome who have autism show different patterns of gene expression than do those with the syndrome who have schizophrenia3.

Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.

But brain cells that had been created using the direct conversion technique had different patterns of gene expression depending on whether they were created from young donors or older adults.

Bhaduri then used statistical algorithms to cluster different cells based on their patterns of gene expression.

Because genes on the Y chromosome often vary slightly in sequence — and even function — from the corresponding genes on the X, males could have slightly different patterns of gene expression throughout the body compared with females, due to not only their hormone levels, but also their entire Y chromosome.

Gene expression profiling tests, such as Oncotype Dx, analyze the patterns of 21 different genes within cancer cells to help predict how likely it is that a women's cancer will recur within 10 years after initial treatment and how beneficial chemotherapy will be to her.

«We showed that these genes have unique expression patterns in different brain regions at varying times during brain development.

Retinas recovering from hypoxia also showed distinct patterns of gene expression that were different from both normoxic control retinas and hypoxic retinas, indicating that hypoxia initiates a complex pattern of gene expression.

It therefore is clear that after 24 h of recovery, the retina remains markedly different than pre-hypoxic controls in terms of gene expression patterns.

The same can be said for patterns of gene expression changes in the same brain region for different age frames.

The research also showed that gene expression patterns of individual tumors varied considerably, and could exceed the variation observed between different cancer types.

Moreover, when analyzed with gene expression patterns of normal brain cells, the four GBM subtypes associate with different cell lineages.

Adipose tissues from various anatomical sites are characterized by different patterns of gene expression and regulation

Massively parallel RNA sequencing (RNA - Seq) was used to investigate in an unbiased fashion the expression of different genes, comparing the control and DAXX K / D expression patterns in PC3 cells (duplicate samples).

This way it is possible to obtain and compare the expression pattern of genes in the FunGenES database to the expression profiles in other tissues, experimental settings, or different stem cells types.

Besides information gathered to answer specific experimental questions, as determined by the interests of individual partners [35]--[41], the collective data offered the opportunity to search for coordinated gene expression patterns in a systematic exploration of the mouse ES transcriptome under a battery of different experimental settings, thus minimizing possible site - specific artifacts.

As an illustration, let us look at the expression patterns of a number of genes identified with different FSVs in the zebrafish embryo.

To better illustrate and map co-regulated genes with different activation and deactivation profiles, the levels of every transcript have been assigned to graphs of «Expression Waves» that follow a particular, predetermined, expression pattern (Expression Waves» that follow a particular, predetermined, expression pattern (expression pattern (Figure 5).