The problems are apparent in two
different gene tests, both discussed in this issue.
Not exact matches
In the current study, Whitney, along with colleagues John Hinson, WSU professor of psychology, and Hans Van Dongen, director of the WSU Sleep and Performance Research Center at WSU Spokane, compared how people with
different variations of the DRD2
gene performed on tasks designed to
test both their ability to anticipate events and their cognitive flexibility in response to changing circumstances.
The
tests especially differ in that they examine
different regions of the viral
gene.
Once the pattern of expression of these
genes had been identified, Prof. Khatri and his colleagues
tested it out on the remaining 900 samples from patients with
different tropical diseases and from healthy people.
The pilot project
tested a dozen or so of the most commonly used
gene promoters (regions of DNA that facilitate
gene transcription) and segments of DNA that encode ribosome - binding sites (sequences of messenger RNA that control protein translation) to determine whether they behave consistently in
different cellular contexts.
For comparison, dsRNAs targeting two
different genes were
tested.
For this study, they created several lines of transgenic Brazilian and African rice that overexpress this
gene, and with their CIAT and JIRCAS collaborators,
tested how well the rice grew in
different conditions in
different years.
Until now, the data and
test results for this ongoing work have all come from preexisting, online digital data sets of
gene expression from patients with
different kinds of infections — not from current patients.
Although many
different malaria resistance loci have been postulated over the years, this is one of very few that have stood up to stringent
testing in a large multi-centre study; the others include the
genes for sickle cell and the O blood group.
To
test whether the new spheroids were a better mimic for functional dermal papilla cells than those that had been grown in typical dishes, Christiano and her team determined what
genes were turned on and off in
different sets of dermal papilla cells.
The researchers isolated the milk ducts and purified the breast - tissue cells to create a cell culture, which was then
tested for
different gene regulation profiles.
They
tested these drugs one at a time for lethal interaction with 112
different tumor - suppressor
gene mutations in human cancer cells growing in the lab.
In the current study, researchers
tested two
different CRISPR
gene drive constructs in the model fruit fly, Drosophila melanogaster, to investigate the rise of resistance.
The researchers
tested this observation by infecting chick embryos with viruses carrying R - fng, causing the
gene to be expressed in many
different places.
To
test their hunch, Duda and Palumbi tracked down the
different versions of a
gene that encodes one type of neurotoxin.
In an attempt to answer the question of whether
genes that show high levels of variability across
different species could also be useful in population - level evolutionary studies, scientists in Brazil, Singapore, and the United Kingdom teamed up to
test the utility of numerous
genes previously found to be useful in inferring relationships of cactus species.
If a mother has two
different versions, or alleles, of a
gene, conventional genetic
testing can't work out which allele she passed on to her child, because her blood contains both.
Tomoaki Sakamoto of the University of Tokyo and his colleagues
tested 34
different varieties of rice plants in which individual
genes had been removed — specifically avoiding an approach in which genetically desirable traits are imported from other plants.
It is the first time that a
gene therapy based on genetically modified stem cells is
tested in a multicenter, international clinical trial that shows a reproducible and robust therapeutic effect in
different centers and
different countries.
Gene expression profiling
tests, such as Oncotype Dx, analyze the patterns of 21
different genes within cancer cells to help predict how likely it is that a women's cancer will recur within 10 years after initial treatment and how beneficial chemotherapy will be to her.
Paleoanthropologists Jean - Jacques Hublin and Luke Premo of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany,
tested this hypothesis by simulating how mating preferences alter
gene flow between individuals in
different groups.
There are
different blood and saliva
tests available for potential breast - cancer
gene mutations.
(At least one
test, Agilent's Mycoplasma Plus PCR assay, is based on a
different bacterial
gene.)
An example of a «candidate
gene» experiment
testing whether
different diploid genotypes are associated with
different trait values, or phenotypes.
There are already well established databases within the consortium, the London Pain Database (LPD) and QUAST (DFNS, Germany): The LPD is used for datamining of functional genomics data to help identify individual
genes and functional networks associated with chronic pain, QUAST on the other hand collects questionnaire data, clinical and neurophysiological findings and calculates valid clusters of phenotypes with
different interaction patterns of sensory loss with and without
different types of peripheral and central hyperalgesia based on QST (quantitative sensory
testing) data.
So far, we've seen
gene silencing drugs
tested in several
different animal models of Huntington's disease, successfully delaying symptom onset or even reversing symptoms.
All they did was they took two
different groups, they
tested their
genes and they had 1 group just do a basic standard exercise protocol.
So, when Seat's friendly neighbourhood racing driver and former WTCC man Jordi
Gene first gets behind the wheel (
testing kicks off just after the Geneva Motor Show), he'll find himself in a car that's radically
different to drive in comparison to the Leon TCR.
Because there is more than one form of PRA, if there should happen to be a second form in the breed and your dog had the
genes for that type it would be possible to
test your dog «for PRA» using the PRCD
test with clear results when the dog is actually affected — but with a
different form of PRA.
The
gene for HCM in Ragdolls is
different from the one in the Maine Coon, but it has been identified and there is a
test for it.
However, as science identifies the
genes responsible for the disease in
different breeds and as DNA screening
tests become available, epilepsy might be included in a breed's CHIC criteria.
For example, the prcd - PRA DNA
test detects one specific mutation in the prcd
gene and the XL - PRA
test detects a specific mutation in a
different gene.
The
test identifies seven mutations in three
different genes which permits identification of the «risk alleles,» which are not causative of GDV but are highly associated.
Doing a genetic
test and subsequently eliminating an individual from the breeding population may not be the best strategy, as by targeting a particular allele at one genetic locus for removal from the
gene pool of a particular breed, breeders may in fact increase allele frequency of genetic variants on alternative haplotypes at the same, or a
different locus, that are recessively deleterious.
POAG - NE mutation
test: A novel mutation in ADAMTS10
gene,
different from previously identified mutation in the same
gene that causes POAG in Beagles, has been found to be associated with POAG in Norwegian Elkhound (1).
«A genetic algorithm
tests different executions based on the strength of their various features or «
genes,» such as copy, layout, font and image.