Sentences with phrase «different gene variants»

Athletigen's process involves taking a sample of an athlete's saliva and subjecting it to genotyping analysis to search for 850,000 different gene variants that may play a role in the formation of athletic traits.

Not exact matches

Some genes have a variety of different forms, which are located at the same position on a chromosome; an allele is such a variant form of a gene.

In fact, the MESA researchers had included 46 different variants of the gene in their sequencing database.

«Now, we know that epigenetic factors accumulate at a very different pace in each person, depending on the genetic variants of the lactase gene.»

Sophien Kamoun of the Sainsbury Laboratory in Norwich, UK, and colleagues report that P. infestans has a genome three times as large as its closest relatives, because it keeps many different variants of its «attack» genes (Nature, DOI: 10.1038 / nature08358).

So scientists can now use the so called gene chips to scan people's DNA for hundreds of thousands of genes and different variants of genes.

In a different sort of analysis, Pipes discovered that all aggressive foxes carry one form of the GRM3 glutamate receptor gene, while a majority of the friendly foxes have a different variant of the gene.

Here's a gene that's central to how nerve cells communicate with each other, so it's curious to us to see a grossly different protein variant.

Sex determining genes exist in several different variants, but close family members are likely to share the same variants.

Five decades on from the appearance of the first MRSA, multiple MRSA lineages have emerged which have acquired different variants of the resistance gene.»

«What we found is that if people have a specific polymorphism in the BDNF gene, they recovered to a greater extent than those with a different variant of the gene.»

What we need to do now is to see if other circadian gene variants in association with different stress factors cause the same effect.

While previous investigations into the protein's effects have used either mice in which gene expression was knocked out or transgenic animals that expressed human gene variants throughout their lifetimes, the MGH - MIND - led study used a different approach to investigate the effects of introducing the variant forms of the protein into brains in which plaque formation had already begun.

Scientists have long wondered what it is about these two variants that accounts for their different associations with genes — H3.1 with inactive genes and H3.3 with active ones.

These variants are found in very different places in the genome: version H3.1 is found only in parts of the genome where genes are not being activated; version H3.3 is present only in places where genes are active.

Mice prefer the smell of other mice with different variants of MHC genes to their own and tend to confirm this preference by mating with mice possessing dissimilar MHC genes.

Several different variants are all uniquely associated with pigmentation near these genes, and variants in these genes have been associated with pigmentation in animals.

«How a drug is going to work on a carrier of the gene variant could be worse or it could be better, but it's likely going to be different,» Connor said.

The genes have many different working variants, but one variant of each gene is much more common than all the others.

Engelhardt's group was responsible for mapping associations between genetic variants and gene expression levels on different chromosomes, a connection known as «trans - expression quantitative trait loci (trans - eQTLS).»

Not only do black - furred dogs and wolves have the same gene variant, but the DNA surrounding the K locus is also quite similar — and quite different from that of gray wolves — suggesting that the variant was introduced when wolves interbred with domestic dogs.

GenProfile focuses on the systematic analysis of DNA sequence variation in biomedically relevant genes in order to identify those variants, or combinations of variants (gene profiles), that determine an individual's genetic risk for disease, predict individually different drug response, and ultimately pave the way to a personalized medicine.

Different versions of the FRO2 gene («variants») fell into two groups, those that were associated with a short root and those that were associated with a long root.

A schizophrenic from Brazil might have a combination of rare - variant genes contributing to the disease that is different from the mix in a schizophrenic from Norway.

By focusing on several of these mutations and screening through guide RNA variants with different mismatch combinations, they were able to identify specific guide RNAs that stimulated Cas9 activity towards the mutated gene sequences but left the normal counterpart untouched.

The Neurogenomiks research group, linked to the Achucarro Basque Centre for Neuroscience (EHUgroup) and the University of the Basque Country (UPV / EHU), has just had a research article published in the scientific publication Journal of Immunology; it details how they have managed to show that the gene known as ANKRD55 produces 3 different transcripts of the messenger RNA, and that the genetic variant associated with MS greatly increases the production of these transcripts.

The teams used different genetic approaches, but both found that one variant of a gene called IL7R boosted MS risk by about 30 %.

A naturally occurring variant in a different gene, the so - called APOE2 allele, has been previously shown to protect against Alzheimer's disease, but Stefansson says the new variant, while rarer, confers much greater protection.

«There are hundreds of candidate genes to sort through, and a single genetic variant may have different effects even within the same family.

Transfers of DNA happen so much that bacteria can have all sorts of different combinations of genes and gene variants.

Analysis of the DNA and encoded amino acid sequences of A14 and B9 revealed that the first two are clonal variants which aligned most closely to the germ line denoted VHH Vg (T Verrips, unpublished data) and that the sequence of B21 is highly divergent from both and also aligns to a different germ line V gene sequence Vu.

The results also showed that polymorphism, a genetic variant that can change the way a particular gene functions, is possible under a wide range of conditions, which results in a single population playing a variety of different behavioral games.

Cardiomyopathy can be caused by a single mutation in any one of a number of genes, each one resulting in a slightly different variant of the disease.

Choose a gene, region or variant and then browse for relevant visualizations that include many different types of figures and tables.

But the variant gene gives slightly different protein - building instructions.

This revealed that both Satellite and Faeder males carry a «supergene» which is not a gene with superpower but a cluster of about 90 genes kept together by a chromosomal inversion which means that there is no genetic exchange between the three different variants.

Recent genetic association studies identified variants in a locus on chromosome 15 (specifically, in the adjacent genes HERC2 and OCA2) that are major determinants of eye color, but the trait is influenced by interaction among at least ten different genes.

«We found that different forms or variants of the human ASIC1a gene appear to be associated with panic disorder.

However, when we extracted gene expression levels from the brain transcriptome data following the methodology in Carneiro et al. [29], we found that levels of nucleotide diversity and the proportion of low frequency variants between lowly (bottom 5 %) and highly (top 5 %) expressed genes in our dataset (Table S7) were not significantly different in most comparisons (with the exception of π in O. c. cuniculus) nor did they consistently differ in the expected direction when assuming higher error rates in lowly expressed genes.

The gene variant for white colour in pigs differs from the gene variant found in wild boar, with at least five different mutations, four of which are duplications of DNA sequences.

At some point in the past, random mutations created a variant of one receptor gene, located on the X chromosome, producing two different receptor types.

According to the scientists, these results show that although the gene variants — which make individual humans different from each other — in general have a small impact on disease development, the gene switches in which they reside can play a major role.

There are many different variants of the MTHFR gene.

Several different variants in the Bestrophin gene (BEST1 (alias VMD2)-RRB- have been identified as likely causal mutations for CMR in the dog.

Doing a genetic test and subsequently eliminating an individual from the breeding population may not be the best strategy, as by targeting a particular allele at one genetic locus for removal from the gene pool of a particular breed, breeders may in fact increase allele frequency of genetic variants on alternative haplotypes at the same, or a different locus, that are recessively deleterious.