Sentences with phrase «different genes in the genome»

Six different genes in the genome could be statistically linked to the sex of Atlantic cod.

Not exact matches

In a study published in Neoplasia, researchers at the Washington University School of Medicine created a map showing which genes were switched on and off in different parts of the tumor, providing a «signature» of these switches throughout the genomIn a study published in Neoplasia, researchers at the Washington University School of Medicine created a map showing which genes were switched on and off in different parts of the tumor, providing a «signature» of these switches throughout the genomin Neoplasia, researchers at the Washington University School of Medicine created a map showing which genes were switched on and off in different parts of the tumor, providing a «signature» of these switches throughout the genomin different parts of the tumor, providing a «signature» of these switches throughout the genome.

The survey, described today in a Policy Forum published by Science, randomly presented people with different vignettes that described genome editing being used in germline or somatic cells to either treat disease or enhance a human with, say, a gene linked to higher IQ or eye color.

Sophien Kamoun of the Sainsbury Laboratory in Norwich, UK, and colleagues report that P. infestans has a genome three times as large as its closest relatives, because it keeps many different variants of its «attack» genes (Nature, DOI: 10.1038 / nature08358).

Comparisons of the Neandertal genome to the genomes of five present - day humans from different parts of the world identify a number of genomic regions that may have been affected by positive selection in ancestral modern humans, including genes involved in metabolism and in cognitive and skeletal development.

The nonredundant protein sets of flies and worms are similar in size and are only twice that of yeast, but different gene families are expanded in each genome, and the multidomain proteins and signaling pathways of the fly and worm are far more complex than those of yeast.

The genome - wide epigenetic changes clustered in certain chromatin domains and controlled «gene expression changes that specify different malignant traits, including the ability to form tumors,» McDonald said.

By compiling a database of 110 different prokaryote genomes, Todd J. Treangen and Eduardo P. C. Rocha of the Pasteur Institute in Paris calculated the number of genes that had been acquired through horizontal gene transfer.

They can thrive in so many different places because their genomes are incredibly flexible: they can alter, lose and duplicate genes almost at will.

The former target, say, using gene editing techniques to inactivate HIV receptors and achieve resistance of blood cells to the virus (which Sangamo BioSciences is working on in clincial trials) is different than helping parents who both carry genes for Huntington's Disease to have a child that is free of the disease (a change to the genome that would be passed on to future generations and would likely not be very commonly needed).

After arriving in their new homes, transferred genes follow a different evolutionary path than do genes that evolve within the same genome.

Because the genome for Dictyostelium has been sequenced, researchers are already deeply immersed in teasing apart different genes and traits that might help explain the differences between farmers and nonfarmers and how the symbiosis might have evolved in the first place.

Another illustrative finding was that the sirt1 nuclear gene, which is an important but controversial gene in aging research, Rand said, shows different effects on longevity given different mitochondrial genomes.

These variants are found in very different places in the genome: version H3.1 is found only in parts of the genome where genes are not being activated; version H3.3 is present only in places where genes are active.

However, Sonia Pascoal, a postdoc in Bailey's laboratory, performed a genome - wide scan that showed that the genes responsible are linked to different genetic markers.

Microsatellites are a gene mapper's dream: not only are they repeated different numbers of times in different people, but they are scattered throughout the genome.

And the third type is a translocation, in which half of the estrogen receptor gene is swapped for a completely unrelated gene from a different part of the genome.

Differences in gene expression may thus explain how largely similar genomes create such different organisms.

Bonthron's team scanned the genomes of six PHO patients from three different families and found that they all had a mutation in the HPGD gene.

She said her research, to understand specific genes» regulatory networks, can be a bridge between genome - wide studies of the ways trees in different environments adapt and the understanding of the role of specific genes in a process.

Mature miR - 7 is individually transcribed and processed from 3 different gene locus in human genome, and it is highly expressed in parts of the brain, eye, and pancreas, suggesting its role in the development of these organs (20 — 22).

Another interesting feature in their genomes is the abundance of transposable elements, «jumping genes» that can move to different parts of the genome to cause mutations or supply new elements to protein - coding genes.

Using machine learning technology, the researchers analyzed hundreds of existing datasets from six different cell types to look for patterns in the genome that identify where a gene and enhancer interact.

Genome editing is used in many different cell types and organisms to specifically modify genes for the interrogation of fundamental cellular pathways.

He studies the evolution of genomes and was the first to show a surprising amount of horizontal gene transfer (transmission of DNA between different genomes) in fungi, challenging our notion of how complex traits evolve within species.

«Having the genomes means we can now go in and systematically ask which genes allow Brucella to preferentially infect different animals,» says Boyle.

Current Predictions of Approximate Gene Number and Genome Size in Organisms in Different Evolutionary Lineages.

The initial goal of the project is to establish a large collection of Drosophila strains that each contain a single genetically engineered P transposable element insertion that mutates a different gene, in a genome free of other P elements.

Thanks to innovations in sequencing technology that have produced a cornucopia of genomes, plus some tweaks to the computational methods by different labs, the combined list of identified HARs now includes nearly 3,000 genome segments.4 But the original trend still holds; nearly all HARs are outside genes, some quite far away from any gene in the genome.

«Riding» different lines in the DNA Subway, users can predict and annotate genes in up to 100,000 base pairs of DNA (Red Line), and prospect entire plant genomes for specific genes (Yellow Line).

«Since two strains of the same species can have such different genomes, you really need to know what genes are there and what role they play in order to link someone's gut microbiota to BMI or disease.»

«Before there was the Human Genome Project, people were studying gene sequences — they were just doing it a million different ways in a million different labs,» Huerta says.

Scientists stitched together the complex genome of the California two - spot octopus, and analyzed 12 different tissues in search of the genes that allow these unique cephalopods to change skin color and control eight arms independently.

The researchers were able to assign these genes to, or reconstruct the genomes in part or in whole for, 87 different bacterial species.

They report that the genes encoding the different subunits of PDE6 in cones and rods arose from ancestral genes that duplicated in the early vertebrate genome doublings, and further expanded in teleosts due to the extra genome duplication that took place in this lineage.

Examples include the study of allelic variation in the human genome and the development of computational methods for the discovery of cancer - associated genes and diagnostic cancer markers using genomic profiles derived from different tumor types.

It is important to distinguish lineage specific gene expression shown here, which occurs at a high level and with a degree of specificity in the different population compartments, to the low level of genome wide transcription observed in ES cells by others [22], or with transcript initiation at many loci noted previously in ES cells [23].

All nine of the new genes discovered had not previously been implicated in skeletal disorders and were discovered by randomly screening different strains of mice engineered such that a single gene had been inactivated in their genome.

An international team of scientists sequenced the genome of the California two - spot octopus — the first cephalopod ever to be fully sequenced — and mapped gene expression profiles in 12 different tissues.

The first step in assessing our hypotheses will be to compare the Black - footed Ferret's genome with that of the domestic ferret in order to identify which genes in the immune system are different.

With the completion and publication of multiple fully sequenced Woolly Mammoth genomes, the Church lab is discovering potential cold climate adaptations in different genes.

To annotate the genome, the team generated transcriptome sequence data — which can be used to measure gene expression based on RNA levels — in 12 different tissues types.

These studies demonstrate that the two important protein complexes, condensin and cohesin, are both essential for the assembly of the functional genome architecture, but their roles in the 3D genome organization (gene contacts and topological domain organization) are significantly different.

Importantly, all of the building blocks of SARS - CoV genome, including the highly variable S gene, ORF8 and ORF3, could be found in the genomes of different SARSr - CoV strains from this single location.

«Even though a microbial genome is one - thousandth the size of the human genome, the total number of microbial genes in [the human] body is much greater than human genes because you have so many different species,» says Weinstock.

By comparing the genome sequence with other whipworm species such as the mouse whipworm (Trichuris muris), the students will identify new or different genes that could play an important role in the biology of the whipworm.