Sentences with phrase «different genes involved»

has done some work looking at the different genes involved in differing parts of lipid metabolism, it may well be there's a subset of the population that does respond badly to saturated fat, just as there's a subset that responds well to high carb low fat diets (obviously these are not mainstream responses or we could all go home!)

There are about 20 different genes involved in atopic derm, and the skin has an issue in maintaining moisture, hence when it is dry out those afflicted suffer, unless they moisturize frequently.

Although this compound exhibits a preference for AT - rich regions, overall it is expected to affect expression of a multitude of different genes involved in diverse biological functions.

Han et al. demonstrated that in Caco2 cells, extracellular NAD + inhibited the binding of NF - kB to DNA by blocking the transcription of different genes involved in both inflammatory and aging pathways (interlukin - 6, interlukin - 1 beta, tumor necrosis factor alpha) 27.

Both Tsigelny and Kurzrock agreed that this finding is an excellent example of the power of collaboration between SDSC and the Moores Cancer Center, and that such modeling needed to be studied across tumors and with multiple different genes involved in cancer.

Not exact matches

Athletigen's process involves taking a sample of an athlete's saliva and subjecting it to genotyping analysis to search for 850,000 different gene variants that may play a role in the formation of athletic traits.

These conditions are each caused by mutations in a particular gene, and affect different enzymes involved in breaking down galactose.

«Through our research we discovered that defense against extracellular pathogens (ETD) involves different plant genes from those involved in the defense against intracellular pathogens.

Because different mutations in the same gene caused the three behaviors, we concluded that per is somehow actively involved both in producing circadian rhythm in flies and in setting the rhythm's pace.

Bernard Friedenson, associate professor of biochemistry and molecular genetics at UIC, looked at the DNA sequences of breast cancers from 21 different women and found mutations in genes involved in immunity in every one of them.

Susceptibility genes for diabetes may be involved in several different metabolic pathways in the body, including storage and release of fat for energy.

Comparisons of the Neandertal genome to the genomes of five present - day humans from different parts of the world identify a number of genomic regions that may have been affected by positive selection in ancestral modern humans, including genes involved in metabolism and in cognitive and skeletal development.

The researchers have compared various processes involved in gene expression, such as gene transcription and chromatin modification, and have repeated this in different tissues and cell types from both humans and mice.

This study showed the two subtypes have different genetic origins and involve a dramatically different number of chromosomal rearrangements, mutations and other gene variations.

With that in mind, the Penn Vet team chose to examine two of their well - established canine models of RP, which recapitulate many features of the human diseases, each involving mutations in different genes.

The study involved extracting Ribonucleic acid or RNA — found in the cells of all living organisms — to develop a transcriptome — the gene readouts in a cell — to examine what occurs during the different developmental stages of the cockroach pregnancy and to explore if those changes hold wider applications for other mammals.

Many hundreds of genes are likely to be involved, with each one playing a role in just a small fraction of cases, and contributing to risk in different ways in different individuals,» said Jones.

Gene drive is so different from other technologies involving genetic modification that it requires a whole new way of thinking about how to evaluate and regulate it, says Jennifer Kuzma, a natural and social scientist at North Carolina State University (NCSU) in Raleigh who helped organize a February workshop there.

«More than 250 genes and gene markers are involved with obesity, so there are obviously many different kinds,» Atkinson says.

But the researchers found no significant changes in the expression of genes known to be involved in calcification from prior studies comparing strains with dramatically different calcification levels.

One person takes a drug and has a set of side effects, all of which could involve different genes.

As a postdoc in the lab of Zefeng Wang, PhD, a member of the UNC Lineberger Comprehensive Cancer Center, Choudhury stumbled upon DAZAP1 while searching for proteins involved in alternative splicing — when a single gene organizes its genetic code to create different proteins with various functions.

The genetic causes of bipolar disorder are highly complex and likely involve many different genes, said Carrie Bearden, a senior author of the study and an associate professor of psychiatry and psychology at the UCLA Semel Institute for Neuroscience and Human Behavior.

The researchers targeted a different gene — one involved with the heart's built - in system for responding to heart attacks and other emergencies.

Lo's team confronted this problem by studying a couple who each carry different types of mutation in a gene involved in making hemoglobin.

Other genetic defects associated with hypertrophic cardiomyopathy — six different genes have been linked to the disease — may work similarly by producing abnormal proteins involved in contraction, says Sweeney.

The two groups, they found, had different versions of a crucial gene, one that coded for a protein involved in pigmentation.

Not only were levels of metabolic compounds different, but the expression of certain genes involved in metabolism was turned up, and the epigenome of the cells — molecular markers on DNA that change gene expression on a broader scale — was altered.

«The catalogue of genes involved in immune defence responses is well conserved among different bee species regardless of their level of social organisation,» explained Dr. Robert Waterhouse from the University of Geneva and the SIB Swiss Institute of Bioinformatics, «but it is much smaller than in solitary insects such as flies and mosquitoes that often live in more pathogen - rich environments.»

«But there are many different genes that could be involved: some control the virus's ability to enter immune cells, others control how the virus tricks cells into expressing its genes.

The current work shows that changes in the genetic code of a particular gene can control epigenetic marks at different genes, implying that a gene's genetic code can affect whether other genes are turned on and off, which makes it important to understand the function of all genes involved, not just the one with the so - called misspelling.

However, for some mouse DNA losses the case may be different, as in the mm10 genomic background they mostly occurred near genes involved in developmental processes.

One of the ten emerging technologies selected was the Human Cell Atlas, which aims to integrate research exploring all the «omes»: the genome (the full set of genes), the transcriptome (the RNA made from all genes), the proteome (the proteins), the metabolome (small molecules, such as sugars, fatty acids and amino acids, involved or generated by cellular processes), and the fluxome (metabolic reactions whose rates can vary under different conditions).

Although most adult leukemias involving MLL affect a different part of the gene, the breakpoints found in infant leukemias and secondary leukemias occur predominantly in the small region altered by the bioflavonoids.

He said they also are conducting field - level gene flow studies involving different genetic backgrounds and will grow harvested hybrid seed to observe growth characteristics and fitness.

Whereas IRF - 9 functions as an adaptor for tethering the different STAT dimers to ISRE, other members of IRF family have also been shown to be involved in the regulation of ISRE - containing genes.

Trypanosome and bacterial challenge result in upregulation of different genes, suggesting that different recognition pathways are involved in the two responses.

One common analysis applied to scRNA - seq data involves detecting differentially expressed (DE) genes between cells in different biological groups.

They hypothesized that mind - body interventions reverse the expression of genes involved in inflammatory reactions caused by stress, and so they conducted a systematic review of 18 different studies that used gene expression analysis in mind - body interventions.

All of these contexts utilize the same gene - based principles of energy metabolism — the biochemical machinery that we all share — but because they all involve different starting points as well as different goals or possible outcomes, they often require different action plans.

The team looked at 3 different genotypes involving adenosine receptor genes to see if any of them would indicate whether or not a person would have increased anxiety when consuming caffeine.

A: Every mutation is different; some are highly predictive of disease, and some are dependent on other factors, such as the breeds involved, or the influence of other genes, the environment, and even diet.

Mutations for monogenic epilepsies have been found primarily in genes coding for ion channels 32 as well as in two different proteins that may be involved in neurogenesis 33.

Their discovery was not accompanied by any attempt to demonstrate that the changes in gene architecture they found also involved a change in the function of the genes or were associated with different effects on bear physiology.

But because of its willingness to get involved in all types of businesses and to try different operational models, the company has the confidence to position itself to succeed in any market, says Gene Brake, Woods» general manager.