Sentences with phrase «different human cancers»
The authors studied a standard panel of 60 established human tumor cell lines representing nine different human cancers, as well as several specimens of human primary ovarian cancer.
http://www.uchospitals.edu/ Not exact matches
Breast milk has been discovered to have cancer - killing properties against many different types of cancer, in a petri dish and in the human body.
Human breast cancers can be classified according to their histological and molecular features into different subtypes, including luminal, ERBB2 and basal - like tumors.
An analysis of the HPV16 genome from 5,570 human cell and tissue samples revealed that the virus actually consists of thousands of unique genomes, such that infected women living in the same region often have different HPV16 sequences and variable risks to cancer.
The researchers tested the drug combinations against four different human cervical cancer cell lines.
In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.
Pre-clinical studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from human breast cancer patient biopsies.
They tested these drugs one at a time for lethal interaction with 112 different tumor - suppressor gene mutations in human cancer cells growing in the lab.
Next, the researchers transplanted metastasizing human colon cancer cells into a different set of mice.
By producing the metabolite 2 - phosphoglycerate, PGAM1 regulates several different metabolic pathways, and the levels of this enzyme are abnormally elevated in various human cancers, including breast cancer, lung cancer, and prostate cancer.
A search of the CRISP database of NIH - funded research projects on three key words — mutant, androgen, and receptor — yields 24 projects funded since 1999 by nine different NIH institutes: the National Cancer Institute (eight projects), the National Institute of General Medical Sciences (NIGMS, three projects), the National Institute of Child Health and Human Development (three projects), the National Institute of Diabetes and Digestive and Kidney Diseases (two projects), and the National Center for Research Resources (two projects).
The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple human cancer cell lines to different chemotherapy agents based on the cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor cells to common classes of chemotherapy treatment.
One circuit senses levels of five different microRNAs, and if the levels match those typically found in human cervical cancer cells, the circuit produces a protein that kills the cell.
«We've seen this in six different types of human cancer cell lines in the lab,» Choudhury said.
«So perhaps in this age of cancer genomics showing how diverse and heterogenous human cancer is, we should be focusing on the common effects that different mutations lead to,» he says.
Linda Buck of the Fred Hutchinson Cancer Research Center and Richard Axel of Columbia University, both winners of the 2004 Nobel Prize in Physiology or Medicine, have found that the human nose contains about 1,000 different types of olfactory neurons, each type able to detect a particular set of chemicals.
Using all the existing data that was available, Andrechek, along with MSU doctoral student Daniel Hollern, analyzed 1,172 mouse mammary tumor samples from 26 different preclinical models and was able to compile one of the largest databases to show which strains of mice were best suited to study a particular type of human breast cancer.
Although most of the work has been carried out using in vivo studies, Asst Prof Gasser has been collaborating with Dr Joanne Ngeow at the National Cancer Centre Singapore to characterise the process in different types of human tumours.
«Our work outlines the genetic similarities of the tissue and cells in different types of tumors and shows the strong relationships mice can have to other human cancers too.»
The research highlights the importance of investigating different cell types in normal human tissues to understand the cellular origin of cancer and the factors that may contribute to its development.
The study analyzed data from The Cancer Genome Atlas (TCGA), a research program supported by the National Cancer Institute and National Human Genome Research Institute within the National Institutes of Health that is looking at genomic changes in more than 20 different types of cCancer Genome Atlas (TCGA), a research program supported by the National Cancer Institute and National Human Genome Research Institute within the National Institutes of Health that is looking at genomic changes in more than 20 different types of cCancer Institute and National Human Genome Research Institute within the National Institutes of Health that is looking at genomic changes in more than 20 different types of cancercancer.
Imaging of human subjects and small animals provides unique information on tissue structure and function, and is being applied in a variety of different applications in neuroscience, cancer research and studies of metabolism.
Kevan Shokat's group at the University of California, San Francisco, is approaching the Ras problem by exploiting the different mutant versions of Ras that are most prevalent in human cancers, and synthesizing compounds to bind specifically to their mutated residues.
the HGM 2012 (Human Genome Meeting 2012 in Sydney; Australia) and a series of PacRim Breast and Prostate Cancer Meetings in 3 different countries, he was a visiting professor at many universities, incl.
In fact, the pathologist is cautious about calling the Colombian's illness «cancer» because those cells were different from normal human cancer cells, even though they behaved similarly.
• Detect Zika virus in blood and urine samples within hours and distinguish between its African and American strains • Distinguish between Zika and dengue • Discriminate different types of bacteria, like E. coli • Detect cancer cell mutations • Detect antibiotic resistance genes • Read human genetic information from saliva sample
Recent genetic research in humans has implicated mutations in the gene for Tet2 as a risk factor for many different diseases of aging, including cancer, cardiovascular disease, and stroke.
She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.
And we can also use what we know about the genetics of the human cancer to make mutations in normal cells, and see how different mutations drive invasion.»
The goal was to deepen the knowledge about the pharmacological and cytotoxic effects of the drug Temodex in vitro in different human brain cancer cell lines.
Researchers are also trying to learn about: - The level of MM - 121 that remains in the human body at different time points when MM - 121 is combined with docetaxel or pemetrexed - The relationship between the biomarker, heregulin, and cancer cell growth (disease progression) in people dosed only with docetaxel or pemetrexed.
To develop the methodology, the group analyzed the molecular profiles of human embryonic stem cells and compared them with data for 12,000 samples of 33 different tumor types held by The Cancer Genome Atlas (TCGA), a U.S. public database.
Dr. Smith, a professor in the Department of Laboratory Medicine and Pathology, wears many hats at the Mayo Clinic, including running a lab where he works on the characterization of the common fragile sites in the genome and on the role that human papillomaviruses play in the development of a variety of different cancers.
Examples include the study of allelic variation in the human genome and the development of computational methods for the discovery of cancer - associated genes and diagnostic cancer markers using genomic profiles derived from different tumor types.
Reykjavik, ICELAND, January 19, 2009 — Scientists at deCODE genetics (Nasdaq: DCGN) and colleagues from the US and ten European countries today announced a long - awaited first in cancer research: the discovery of common single - letter variations in the human genome (SNPs) linked to susceptibility not of one, but several different types of cancer, including those of lung, bladder, prostate, skin and cervix.
Animal models also help, but cancers in research animals such as mice are different from those in humans.
This year, though, a landmark study was published, pitting 34 common vegetables against eight different types of human cancers.
I wouldn't say this was a «great» article... Seems clear to me too that Jobs probably died because of his diet too tho... but what this article doesn't talk about is the health / unhealthiness of anyone who ate what jobs did but then also added meat and how long they lived or what diseases they had / or if they lived to be 110 years old... or someone who ate a different type of vegan diet like one with appropriate good proportions of whole foods in a plant based diet with fruit and no juice and how healthy or idk i've never heard of someone eating a good / human appropriate vegan diet and developing cancer but if one exists / existed i would imagine this site would of found them don't you?
Tests on animals and humans alike show that HAMLET kills over 40 different types of cancer cells, all without harming healthy cells.
The problem with cancer in dogs, as with humans, is that it comes in many different forms.
Unfortunately, just like humans, dogs also suffer from different types of cancer and because of this they must be kept a close eye on if they begin to lose weight really quickly for no apparent reason, are excessively tired and start acting usually down.
Recent studies in humans suggest that growth is a risk factor for a number of different cancers.»
Chromosome aberrations have been collated from assessment of over 62,000 human neoplasms, collectively representing approximately 75 different types of cancer.
Studies of dogs and cancer detection are based on the fact that cancerous cells release different metabolic waste products than healthy cells in the human body.
As dogs are a subspecies but their breeds are distinct genetic units, and because only certain breeds share the same type of cancers as humans, the differences in the genes of different breeds may be useful in human medical research.
FDA approval and on - going clinical trials attest to the potential of VEGF inhibition as a treatment for many different cancer types in humans, however, the therapeutic effects of VEGF neutralization on cancer growth and metastasis have not been evaluated in the dog.
Cell - based vaccine strategies that stimulate anti-tumor immunity have shown promise in the treatment of many different cancer types including non-Hodgkin's lymphoma (NHL) in humans.
Pets have a risk of developing different types of cancer just as humans do.
By noting patterns of cancer development, doctors and veterinarians may become aware of environmental factors that could be causing tumor progression in different species, including humans.»
This is very different from humans, where Helicobacter can cause serious irritation and even stomach cancer.