Based on the resource of more than 47,000 antibodies and a panel of > 20
different human cell lines, this facility has a unique position to investigate subcellular spatial proteomics for human and rodent biology.
Not exact matches
The work, funded by the US National
Human Genome Research Institute, aims to create human cell lines with subtly different genomes in order to test ideas about which mutations cause disease and
Human Genome Research Institute, aims to create
human cell lines with subtly different genomes in order to test ideas about which mutations cause disease and
human cell lines with subtly
different genomes in order to test ideas about which mutations cause disease and how.
The researchers tested the drug combinations against four
different human cervical cancer
cell lines.
As those
cells proliferated in laboratory dishes, the bits of
human DNA were also copied, creating
cell lines, each of which had a
different fragment.
In a paper published online yesterday in Stem
Cells, the researchers report that they succeeded in generating pluripotent human ES cell lines — i.e., cells that can develop into many different kinds of cells — from one of the 13 late - arrested emb
Cells, the researchers report that they succeeded in generating pluripotent
human ES
cell lines — i.e.,
cells that can develop into many different kinds of cells — from one of the 13 late - arrested emb
cells that can develop into many
different kinds of
cells — from one of the 13 late - arrested emb
cells — from one of the 13 late - arrested embryos.
The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple
human cancer
cell lines to
different chemotherapy agents based on the
cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor
cells to common classes of chemotherapy treatment.
«We've seen this in six
different types of
human cancer
cell lines in the lab,» Choudhury said.
Yet, «these studies using HeLa
cells had to rely on information from the «reference» sequence produced by the
Human Genome Project, even though there was evidence that the genomes of HeLa
cell lines were probably quite
different,» said Lars Steinmetz, Ph.D., who led the G3 study.
They tried hundreds of
different recipes; eventually they discovered that if they mixed liver precursor
cells (derived from iPS
cells) with two other types of standard
human cell lines known to be important for embryonic liver development, then the
cells would spontaneously form a 4 to 5 - millimeter 3D structure called a liver bud.
Initially, the Geneva researchers observed the vascularisation processes of
human tumour
cells from
different cell lines.
The authors studied a standard panel of 60 established
human tumor
cell lines representing nine
different human cancers, as well as several specimens of
human primary ovarian cancer.
Panel A. Staining for HNF4α was performed on enhanced hiPS - HEP
cells from three
different hiPS
cell lines (C12, C18, and C22) on Day 12 post-thawing and cryopreserved
human primary hepatocytes (hphep
cells) on Day 1 post-thawing.
We developed and implemented such a nomenclature for the European
human pluripotent stem
cell registry (hPSCreg), which needs to: 1) unambiguously identify a registered
cell line; 2) allow tracing of subclones of a particular
line; and 3) enable the assignment of
different lines to a specific donor origin.
The goal was to deepen the knowledge about the pharmacological and cytotoxic effects of the drug Temodex in vitro in
different human brain cancer
cell lines.
Originally three
cell lines, U-2 OS, A-431 and U-251 MG, originating from
different human tissues were chosen to be included in the immunofluorescent analysis.
QRT - PCR analysis of GDF - 3 expression in immunologically defined subpopulations of four
different human ES
cell lines.
Year 6 Science Assessments and Tracking Objectives covered: Describe how living things are classified into broad groups according to common observable characteristics and based on similarities and differences, including micro-organisms, plants and animals Give reasons for classifying plants and animals based on specific characteristics Identify and name the main parts of the
human circulatory system, and describe the functions of the heart, blood vessels and blood Recognise the impact of diet, exercise, drugs and lifestyle on the way their bodies function Describe the ways in which nutrients and water are transported within animals, including
humans Recognise that living things have changed over time and that fossils provide information about living things that inhabited the Earth millions of years ago Recognise that living things produce offspring of the same kind, but normally offspring vary and are not identical to their parents Identify how animals and plants are adapted to suit their environment in
different ways and that adaptation may lead to evolution Recognise that light appears to travel in straight
lines Use the idea that light travels in straight
lines to explain that objects are seen because they give out or reflect light into the eye Explain that we see things because light travels from light sources to our eyes or from light sources to objects and then to our eyes Use the idea that light travels in straight
lines to explain why shadows have the same shape as the objects that cast them Associate the brightness of a lamp or the volume of a buzzer with the number and voltage of
cells used in the circuit Compare and give reasons for variations in how components function, including the brightness of bulbs, the loudness of buzzers and the on / off position of switches Use recognised symbols when representing a simple circuit in a diagram