Sentences with phrase «different mechanisms of action»

In the present study, we have demonstrated that rat pups exposed to DPP - IV inhibitors with different mechanisms of action in the early postnatal period might develop persistent behavioral disorders.

«Due to our prior successes in treating these patients with sorafenib and lenvatinib, patients are doing better, but they still ultimately progress, and we need additional agents with different mechanisms of action,» Brose said.

Researchers have found a number of different mechanisms of action for curcumin, and part of the answer as to why curcumin appears to be such potent medicine is because it can:

This is very different mechanism of action than other agents that also effect angiogenesis by inhibiting vascular endothelial growth factor (VEGF) such as bevacizumab (Avastin; Genentech).

«B. bacteriovorus kills bacteria by a whole different mechanism of action than classical antibiotics, and as such, predatory bacteria might in the future constitute a viable alternative to these antibiotics,» Koster says.

In the mouse model, treating node metastases with two angiogenesis inhibitors that have different mechanisms of action did not change the density of blood vessels or the growth of the metastases.

We are developing cutting - edge discovery platforms and product strategies for effective cancer immunotherapies that we believe take into consideration the limitations of other approaches, as well as leveraging different mechanisms of action to address the risk of reliance on a single approach.

That being said, sometimes inadequate dietary iron IS indeed the root cause of the issue, in which case, our Spleen product should be considered due to a totally different mechanism of action and the high heme iron content (5Xs more than liver) either in combination with the Liver (or) as a stand alone product.

Fetal and neonatal exposure to three typical environmental chemicals with different mechanisms of action: mixed exposure to phenol, phthalate, and dioxin cancels the effects of sole exposure on mouse midbrain dopaminergic nuclei.

What makes the study also significant is evidence that Rigosertib did not inhibit its reported target genes; there is reason to believe that the drug has a different mechanism of action at molecular level than anticipated.

«It's a different mechanism of action,» says Craik, who has tested the new drug in animals and hopes to begin human trials within two years.

«In addition, the different mechanism of action in comparison to other drugs for obesity creates an opportunity for combination drugs for the treatment of obesity,» Mantzoros said.

The Vanderbilt researchers believe that the current standard of care for Alzheimer's disease, cholinesterase inhibitors, has a different mechanism of action.

TRIP - Br2 appears to have a different mechanism of action than transcriptional co-regulators reported in previous studies,» says Dr. Kulkarni.

[22] The potential of synergies arising from these different mechanisms of action, the safety and lack of dose - limiting toxicities of the intralesional therapies, and the nonoverlapping toxicity profiles of the contemplated combinations, offer an attractive rationale.

Each component of the stack should utilize a different mechanism of action to achieve the end goal of losing weight / fat (or whatever the athlete's goal is).

A: It is a very good rule of thumb to run any test booster for only 8 - 12 weeks, and to take an 8 - 12 week break after or switch to a supplement that works through a different mechanism of action.

Besides, different diet pills have different mechanisms of action.

It has a different mechanism of action, which may work better for you.

Citrus bergamont is a newer option which has a different mechanism of action in the body than red yeast rice.

Each has a different mechanism of action, so they work together like a «1 - 2 punch» to keep your defenses strong.