Not exact matches
Hospitals use these medications for in - patients only, so those
drugs operate in a largely
different market than the rogue prescription
drugs, heroin and fentanyl fueling the nationwide
opioid epidemic, which claimed 268 lives in Erie County alone last year.
Because GABA B is in a
different class from
opioid receptors, potential side effects in such a
drug would be limited.
Scientists are searching for a
different kind of shot to prevent such tragedies: a vaccine to counter addiction to heroin and other
opioids, such as the prescription painkiller fentanyl and similar knockoff
drugs.
Bohn and colleagues figured out that mu
opioid receptors — the type of
opioid receptor targeted by most
drugs — send two
different streams of messages.
His team showed that mice lacking a
different opioid receptor, the delta receptor, tended not to show negative effects in response to the
drugs.
Despite the potential for new, better
opioids, other researchers are focused on an altogether
different set of pain - killing
drugs: the cannabinoids (made famous by marijuana, the dried leaves and other parts of the hemp plant, Cannabis sativa).