Sentences with phrase «different small molecules»

At Vertex, she's testing different small molecules in the hopes of finding candidates that prevent blood cells from sickling.

Not exact matches

On its own, the immune system boasts different molecules that detect harmful intruders, eradicate small infections and work to contain larger outbreaks.

The apparent gap between nonliving and living has now been bridged by nucleic acids, a class of polymeric organic molecules composed of a succession of small units (nucleotides) of four sorts, the order of which determines an indefinitely large number of different specificities.

Today the living world consists of at least ten million different small organic molecules and at least one trillion different proteins.

«When small molecules are administered, they can stick to many different proteins in the body because their size enables them to interact with many targets, not just the intended target, causing more side effects.»

«Two big advantages to the small - molecule catalysts we've developed are that they are very general — they can work on many different amino acid and peptide structures — and they are very easy to use.

The research centres on miRNAs, small molecules that have an important role in turning genes on and off in different parts of the body.

They demonstrated that their machine could build 14 different classes of small molecules, including ones with difficult - to - manufacture ring structures, all using the same automated building - block assembly.

By tweaking the smallest units of life, scientists are making bigger gains in producing alternative and renewable energy, with recent efforts aimed at molecule - level controls and promoting fractal growth patterns to create different fuels and improve efficiencies.

Green explains that siRNAs must be encapsulated in particles that are different from those used to carry DNA because siRNAs are about 250 times smaller than the DNA molecules usually used for gene therapy.

The team wanted to make the smaller, more flexible molecules better and efficient antimicrobials by attaching them to the carbon nanodot scaffolding, so they built two different molecules: CND - PAM1 and CND - PAM2.

A riboswitch is a short piece of RNA that can fold into different structures, depending on whether or not a small messenger molecule is binds to it.

Small shining molecules developed by scientists at Linköping University in Sweden can be designed to distinguish between plaque of different proteins in the brain.

The larvae are also permeable to small molecules, which will allow scientists to batch - test different drug compounds against the infection relatively quickly and easily, said co-author David Tobin, Ph.D., assistant professor in molecular genetics and microbiology and immunology at Duke.

«Although the two types of inhibitory neurons are very similar to each other in terms of morphology, synaptic connectivity, and the kinds of small molecules they use for signaling, they're very different in terms of the methylation pattern.

The aperture restricts light exposure to a very small fraction of a sample, limiting damage to cells and fluorescent molecules, and the method can be used to image multiple colors at the same time, so scientists can simultaneously track several different proteins.

They are responsible for adding sugar molecules to numerous different types of proteins, whether it's a cell wall, or it's a small signaling peptide, which is what's responsible for the phenotypes in tomato.»

Bacteria are incredibly small, yet pack an enormous diversity of different molecules such as DNA, mRNA and proteins.

Side chains are essentially small molecules of different shapes, sizes and chemical natures attached to the longer lipid - like peptoids.

Levels of a small non-coding RNA molecule called let - 7 appear to define different stages of cancer better than some of the «classical» markers for tumor progression, researchers from the University of Chicago report in the June 25, 2007, early online edition of the Proceedings of the National Academy of Sciences.

(That's different from manufacturing a small - molecule generic, which will have the exact chemical structure of the brand - name drug.)

So the nascent pharmaceutical industry took a different tack, using a series of techniques to produce small - molecule drugs.

Among their many uses, these small molecules stabilize membrane proteins in specific different active conformations for crystallization and detailed structural analysis.

One of the ten emerging technologies selected was the Human Cell Atlas, which aims to integrate research exploring all the «omes»: the genome (the full set of genes), the transcriptome (the RNA made from all genes), the proteome (the proteins), the metabolome (small molecules, such as sugars, fatty acids and amino acids, involved or generated by cellular processes), and the fluxome (metabolic reactions whose rates can vary under different conditions).

Then for postdoctoral research I moved to Yale University, where I worked in a lab that looked at all kinds of different disease areas using the approaches of a field called chemical biology, which is using small molecules — chemicals — to probe biological systems in the hopes of developing compounds that could be new drugs.

Such a similarity makes TNFΔARE a unique model of a complex human pathology appropriate for the simoultaneous testing of novel therapeutics and small molecule inhibitors on two different pathologies.

The molecules we have been working with all start with the same basic skeleton but we tweak them in different ways, so we make it a little bit bigger here, smaller there, we swap out a methyl group for a hydroxyl group.

A number of different strategies are being pursued, including small - molecule drugs and antisense therapies, all with the same goal in mind: to therapeutically boost the levels of full - length SMN protein.

The membrane of the small intestine allows only very small nutrients and fats, proteins and starches which are all broken down to very small particles to enter into the bloodstream, while the larger molecules and many different types of toxic compounds are kept out.

Caffeine is a small molecule present, not only in coffee, but also many different types of teas (except herbal teas); including green tea; energy drinks,

Use different lab equipment and arrange atoms to make ring, linear, small or big molecules and have fun.

Each of these research samples is a small organic solar panel made from different molecules, with varying degrees of transparency to visible light.

In explaining that «[m] any thoughtful and decent people are conflicted about, or strongly oppose, this research,» President Obama was acknowledging that, even in its earliest stages, the small group of cells that constitute an embryo are in some way different from a chemical reagent to be sold in a catalog or an industrially synthesized molecule to be integrated into a widget.

If, to take a very simple example, there were two molecules of ink and 14 molecules of water, in a 4 x 4 array, there are 16 x 15 / 2 = 120 different arrangements of the ink, only a small number of which have the two ink molecules adjacent.

Because different color LEDs offer different brightnesses and shelf life, particularly the blue light which degrades the quickest, panel manufacturers can opt to use different LED materials, such as small molecule, polymer, or phosphorescent, to optimize their design.