Each of us develops from an unspecialized single cell into hundreds of
different specific cell types.
Not exact matches
«Just as normal
cells with the same genome differentiate into many
different cell types, a single tumor characterized by
specific genetic mutations can contain many
different types of
cells — stem - like and more differentiated
cells — with the difference being rooted in their epigenetic information.
«Unlike previous studies we isolated
different immune
cell types from the actual site of disease to determine whether
specific subsets of immune
cells (
specific T
cell groups) have equal sensitivity to vitamin D.»
The transplanted stem
cells differentiated to
different types of
cells with variable level of maturation,
specific for the nervous system.
The
specific pattern of epigenetic marks in a
cell type specifies identity and this epigenetic control is vital to what makes our
cells different, for example a skin
cell from a liver
cell, when they all contain the same genetic instructions.
In the
different cell types, the loops begin and end at
different specific chromosomal locations, so each
cell line's genome appears to have a unique population of loops.
Different GPCRs showed up on different neurons, allowing the scientists to parse specific cell types that might direct particular vagus nerve f
Different GPCRs showed up on
different neurons, allowing the scientists to parse specific cell types that might direct particular vagus nerve f
different neurons, allowing the scientists to parse
specific cell types that might direct particular vagus nerve functions.
This finding suggests their approach could be tailored to generate
specific cell types for patients with
different types of hypopituitarism.
Another example being explored by Wong and others is to engineer stem
cells so they develop into
specific cell types when prompted by
different signals.
Different types of tumors show a preference for
specific organs and tissues; circulating breast cancer
cells, for example, are likely to take root in bones, lungs, and the brain.
By recognising the
different flags with highly
specific antibodies, the researchers could accurately distinguish between the two stem
cell types.
While it is generally accepted that MSC are mostly quiescent during postnatal life, MSCs in
different niches can presumably differentiate into the
specific cells of closely related niches during physiological turnover, injury or disease, as shown for other stem
cell types (e.g., muscle satellite
cells).
We can obtain iPS
cells from an individual's skin or blood and program them into
different tissue
types to create patient -
specific Organ - Chips.
Specific emphasis will be given to various microfluidic designs targeted for use with
different cell types.
cell types may have evolved through cooption of temporal gene regulation in an ancestor whose
different phases were converted into germ - and soma -
specific expression programs.
These results suggest that V. carteri
cell types may have evolved through cooption of temporal gene regulation in an ancestor whose
different phases were converted into germ - and soma -
specific expression programs.
Luckily,
different cell types tend to have
different things on their surfaces, which play particular parts in their specialized roles in the tissue, so it is a matter of identifying and targeting
cell - surface markers that are
specific to these abnormal
cell types.
During development,
cells have to integrate
different types of molecular and physical information to proliferate, and to make decisions such as whether to maintain pluripotency or trigger differentiation and acquire specialisation for tissue -
specific functions.
The co-incidence of these 2 pathologies occurs also in humans suggesting a common pathological mechanism moving across the gut - joint axis, with TNF signals acting on
specific cell types directing pathogenesis at two
different locations.
Other
cells are multipotent, meaning they can generate a few
different cell types, generally in a
specific tissue or organ.
Although we have seen that sponges and eumetazoans share many common pathways related to morphogenesis and
cell -
type specification, there are notable genomic differences, including
different microRNA assemblages46, lineage -
specific domains and domain architectures, and the differential expansions of gene families.
We anticipate that
different cell types will require a distinct cocktail of pluripotent factors, under
specific timing and expression conditions.
In the
different cell types of the body,
different protein producing genes are active or inactive, and many medical conditions also depend on altered activity of
specific genes.
a) In the subsection «
Cell type -
specific NMDA - R pharmacology in cocaine - induced synaptic plasticity» we now more clearly introduce the Zweifel and Engblom studies as well as the differences between them: both of which used genetic ablation of Grin1 over 1 week but showed
different results with respect to DA neuron synaptic potentiation, which was due to methodological challenges with AMP - R compensation.
Non-Hodgkin lymphoma — sometimes also called non-Hodgkin's lymphoma or just NHL — covers a number of
different cancers that start in a
specific type of white blood
cells called lymphocytes.
Unlike NHL, which has many
different subtypes, Hodgkin lymphoma is mostly distinguished by the presence of what's called Reed - Sternberg
cells, or abnormal
types of a
specific lymphocyte.
As time passes and the
cells start dividing further and further, they start specializing into becoming a
specific type of tissue which has a
specific function, thus forming all the
different parts that comprise a human.
The immune system is made up of a team of
different types of
cells that, while each having their own
specific function, work together to protect the body from foreign invaders: B -
cells produce antibodies; T -
cells conduct surveillance for potentially dangerous molecules and kills dangerous
cells such as disease - causing bacteria; and macrophages are the scavenger
cells of your body acting like garbage trucks, cleaning up residue and removing potentially dangerous substances.