As cells divide and differentiate, changes in transcriptional profile occur, leading to considerable phenotypical diversities forming
different subpopulation of cells and tissues in living organisms.
If, however, the scientists showed a picture of the opposite orientation,
a different subpopulation of neurons would respond with a flurry of activity.
As a follow - up to this study, our current grant from the NCI supports testing a tablet - based self - persuasion intervention to address the needs of
different subpopulations at Parkland — adolescent girls and boys, Hispanics, and African - Americans,» said Dr. Tiro.
For Helicobacter pylori, a pathogenic bacterium that colonizes over 40 percent of the world population and is associated with gastric cancer, the team discovered that epigenetic heterogeneity can quickly emerge as a single cell divides, and
different subpopulations with distinct methylation patterns have distinct gene expressions patterns.
As the animal moves,
different subpopulations of these cells become active depending on distance and direction, creating an internal map of its trajectory.
Cancers contain genetically
different subpopulations of cells, called subclones.
Apart from correlational studies that link MDI data to other measures, future studies also need to explore to what extent the MDI measures constructs similarly for
different subpopulations.
As we noted earlier, when studying whether a preventive intervention works differently for
different subpopulations, most investigators have focused only on general population characteristics such as gender or ethnicity.
Not exact matches
«As a result, we can now see the presence of multiple distinct
subpopulations in Europe and in Asia, and these in turn contribute
different amounts of ancestry to more recent
subpopulations.»
Rather,
subpopulations seem to be geared for
different stimulus types, now including music.
As another advantage, APC - mimetic scaffolds enabled us to tune the ratios of
subpopulations of T cells with
different roles in the desired immune responses, which in the future might increase their functionality,» said David Zhang, the study's second author and a Graduate Student working with Mooney.
He adds that the concept seeks to balance relationships both among
different species and among
subpopulations of a given species such as age groups, gender groups or regional schools.
The samples were then analyzed with a technique called polymerase chain reaction (PCR), used to amplify specific nuclear «microsatellites» for statistically measuring gene flow between the
different populations and
subpopulations located in the western South Atlantic (Breeding Stock A) and the eastern South Atlantic and Indian Ocean populations (Breeding Stocks B and C, and the Arabian Sea humpback whale population, respectively).
The authors point out that the findings support previous observations of individual male whales moving between populations in
different ocean basins, and that
subpopulations from both regions could share the same feeding ground in Antarctic waters.
In the past several years there has been growing evidence supporting this notion, revealing
subpopulations of cells representing
different arms of the immune system, as potential regulators of the immune system.
Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem cell - like
subpopulations, by a host of
different mechanisms which comprise inhibition of signaling pathways, of mitochondrial respiration, as well as of cellular stress responses and others.
The commentary highlights the possible fundamentally
different and even opposing functions of intestinal fibroblast
subpopulations in regulating inflammation and tumour formation and underscores the need to further characterize these cells to reveal new mechanisms underlying pathogenesis of chronic inflammation and cancer.
In particular, diversity of the nuclear genome is unlikely to be reciprocally monophyletic among
subpopulations, a phenomenon called incomplete lineage sorting, which results in support for
different topologies across loci (27).
We show that
subpopulations of human astrocytes, generated by activation of
different signaling pathways in the same population of human glial precursor cells, have markedly
different effects when transplanted into the injured spinal cord.
Interestingly, while these
subpopulations are equivalently and clonally interconvertible under self - renewing conditions, when induced to differentiate both in vivo and in vitro they exhibit
different behaviours.
While it has been demonstrated previously that more differentiated cells demonstrate a lower reprogramming efficiency [11] and
different somatic cell types possess differential reprogramming ability [12], [13], no study to date, to our knowledge, has identified
subpopulations of cells within a primary cell population possessing differential reprogramming potential.
In contrast to germline variants, somatic variants are not propagated to the whole individual but to a
subpopulation of cells in the body, with the final consequence that adult human tissues are a mosaic of genetically
different cells.
Table below the Figure indicates the proportion of cells in each
subpopulation for the
different cell lines.
QRT - PCR analysis of GDF - 3 expression in immunologically defined
subpopulations of four
different human ES cell lines.
The present study illustrated that certain
subpopulations of the purebred dog population were more likely to display certain conditions while other
subpopulations were not statistically
different than mixed - breed dogs in terms of disease prevalence.
These inconsistencies likely arise because of two reasons: (a) the literature is sparse with individual studies covering distinct time periods and examining distinct
subpopulations and (b) the various studies use
different operational definitions for age heterogamy (Drefahl, 2010; Rose & Benjamin, 1971; Shehan et al., 1991).
It may also be of special interest to study clinical
subpopulations known to have
different affective experiences than the average population.