Sentences with phrase «different time points when»

Researchers are also trying to learn about: - The level of MM - 121 that remains in the human body at different time points when MM - 121 is combined with docetaxel or pemetrexed - The relationship between the biomarker, heregulin, and cancer cell growth (disease progression) in people dosed only with docetaxel or pemetrexed.

Not exact matches

Two are equidistant from the warehouse, so I split my time between both, and with 100 % consistency at both locations, despite being under different management operators (I asked for the sake of this article to ensure it did not bias my arising point) when I order four Munchkins, they put six in the bag, when I order ten Munchkins, when put twelve in the bag, etc..

At different times investors would like correlated returns when markets are rising, uncorrelated returns when they're falling, absolute returns during a correction, downside protection against a crash, the ability to go both long and short in a sideways market, the ability to be tactical and time the market at the inflection points and, of course, you have to consistently beat the market.

So since everybody cherry - picks verses from the Bible, the only time you will ever get accused of cherry - picking is when they don't like the verses you picked to prove your point, because the verses they cherry - picked prove a different point.

This diversity is different from other epochs - for example, the time when a Princeton scholasticism dominated the 19th - century Protestant landscape, or even the recent period when neo-orthodoxy was at the least the common reference point for theological debate.

If at any point in time Golubka Kitchen decides to make use of any personally identifiable information on file, in a manner vastly different from that which was stated when this information was initially collected, the user or users shall be promptly notified by email.

I've got a smaller bundt pan and need to cut the bake time in half (I point this out because I didn't know they came in different sizes when I bought mine)

That's different from whether they have «0.0 leverage», and its also a point where there's no way to know who will be available when the time comes.

If I wanted to be a disingenuous putz, I could pretend that comparison meant something (as if the bodies of a high schooler and a grown - ass professional athlete wouldn't be markedly different), and I could point out that Jones sure had a noticeable dip in production when he turned 32 and then suddenly got much better (as if that kind of variance doesn't happen in baseball all the freaking time).

Let's face it goalkeepers tend to march to the beat of a different drum and Szczesny certainly fell into that category, but most of his antics were relatively harmless and simply reflected a certain level of immaturity that isn't uncommon for someone thrust into the limelight at such a young age... lord knows we've seen that happen with numerous players throughout the years and very few were ever banished for such behaviour... the only on - field action that drove me crazy was his inability to take a deep breath and not try to rush the play with an ill - timed throw at certain points in the game when common sense suggested holding the ball and slowing things down... the fact that he continued to do this probably had a lot to do with the glaring lack of coaching time spent with the goalkeepers... ultimately he made the fateful decision to take his frustrations out into the public sphere and paid dearly for it... in the end, his services were wanted by several of the best Italian squads, which is significant considering the historical importance placed on the defensive side of the ball in Serie A... all I know is that if someone asked me to pick the most athletically gifted goalkeeper we have had in our squad since the arrival of Wenger, without hesitation, he would be my pick and for that reason his departure is more than a little disappointing... what else is new though

If at any point in time Birmingham Fun And Family Magazine decides to make use of any personally identifiable information on file, in a manner vastly different from that which was stated when this information was initially collected, the user or users shall be promptly notified by email.

Discerning when you step into the role of an educator or advocate is another decision point that a person might weigh several times throughout a day, and the answer might change in different circumstances.

The UW team chose to study hunting weapons from the time of the earliest archaeological record in Alaska (around 10,000 to 14,000 years ago), a time that is less understood archaeologically, and when different kinds of projectile points were in use.

Such investigations are only possible when studies measure risk factors and health outcomes at different time points, and results are analysed with appropriate techniques.

In a matter of seconds, when you put the food in the fryer, water starts evaporating, vapors form and escape the surface, oil penetration starts, and heat begins to rise while at the same time there's evaporative cooling off at different points in the food.

Microarray analysis was performed at different time points to determine yeast genome - wide response when exposed to salt, acid, hypoxic conditions, and hydrogen peroxide, as well as ethanol, isopentenol, and other biofuels candidates.

This is a good point: in a sense each generation has its own sub-culture and if you are from a different sub-culture then there will be times when you can not quite see eye to eye or share the same ideas or feelings.

Life here began in Old Town, with its medieval roots; society was very different back when this part of town was still fresh faced and spry, though some of the old inns still stand if you feel like sampling a date from the heady and seductive Dark Ages... Then take a stroll through New Town, dripping in Georgian decadence; here, you will be reminded that once upon a time the dating scene was a raucous, dangerous place, full of lust and lewdness... Okay, perhaps not all that much has changed, but the point we are trying to make is that Edinburgh's dating scene has shifted across the centuries to become what it is today — fairly sedate compared with the city's tumultuous past, but no less magical or intoxicating.

A reality series in which a man and a woman date two different naked suitors on a remote exotic There was a time when reality TV was considered innocuous and then there was a turning point.

When I examine the effect of winning a school lottery separately at different points in time after the lotteries were conducted, however, I find larger effects in later years.

objectives include: Year 6 objectives • solve problems involving the calculation and conversion of units of measure, using decimal notation up to 3 decimal places where appropriate • use, read, write and convert between standard units, converting measurements of length, mass, volume and time from a smaller unit of measure to a larger unit, and vice versa, using decimal notation to up to 3 decimal places • convert between miles and kilometres • recognise that shapes with the same areas can have different perimeters and vice versa • recognise when it is possible to use formulae for area and volume of shapes • calculate the area of parallelograms and triangles • calculate, estimate and compare volume of cubes and cuboids using standard units, including cubic centimetres (cm ³) and cubic metres (m ³), and extending to other units [for example, mm ³ and km ³] • express missing number problems algebraically • find pairs of numbers that satisfy an equation with 2 unknowns • enumerate possibilities of combinations of 2 variables • draw 2 - D shapes using given dimensions and angles • recognise, describe and build simple 3 - D shapes, including making nets • compare and classify geometric shapes based on their properties and sizes and find unknown angles in any triangles, quadrilaterals, and regular polygons • illustrate and name parts of circles, including radius, diameter and circumference and know that the diameter is twice the radius • recognise angles where they meet at a point, are on a straight line, or are vertically opposite, and find missing angles • describe positions on the full coordinate grid (all 4 quadrants) • draw and translate simple shapes on the coordinate plane, and reflect them in the axes • interpret and construct pie charts and line graphs and use these to solve problems • calculate and interpret the mean as an average • read, write, order and compare numbers up to 10,000,000 and determine the value of each digit • round any whole number to a required degree of accuracy and more!

There are different points in the year which expose the condition known as «teacher tiredness»: the festive, nativity filled run up to Christmas; half way through the year when the mornings and evenings are dark and daylight is at a premium; the long, long summer term stretch and any time when there is an imminent phone call from some friendly inspectors.

When giving directions, address one point at a time and provide clear, short, and written guidelines that are visually accessible to students from different places in the classroom.

It was found that printing fluency, which we arbitrarily defined as 40 LPM or faster, is achieved at different times by different children, and that such fluency is an excellent indicator of when children will learn to read, as well as indicating which children have become successful at reading at any particular point in time.

What should you focus on when you're being pointed in 20 different directions, and all roads are potentially huge time sucks?

First of all, as Susanne Alleyn points out in her clever and very readable book, Medieval Underpants and Other Blunders: A Writer's (and Editor's) Guide to Keeping Historical Fiction Free of Common Anachronisms, Errors, and Myth, an author of historical fiction needs to recognize that the city of today can be vastly different from the city of whatever time period you are writing about, and this is true even when you are talking about a relatively young city like San Francisco and a time period that is only 132 years in the past.

When the Times allows a poorly researched, inaccurate anti-Amazon screed to appear, it makes me want to stand up for Jeff Bezos and Amazon, and present a very different point of view which I hope will balance out what I consider blatant propaganda.

Retirement may look different for each person; but when you boil it down to its basics, it is the point in time from which you derive most of your income from your investments (your capital) instead of from your job (or labor).

Also same advisors say various sectors will do well at different point of times, what better time to buy into a sector than when it is down.

When it's time to redeem your points, you have different options: pick from gift cards, merchandise, charitable donations, or you can go for good old - fashioned cash.

If you prefer gift cards, you will have a lot of different gift cards to choose from when it comes time to redeem your points.

You just enter five data points (asset name, dollar amount of it held, when it pays, and its annualized estimated yield - get it from the fund's prospectus, website, other source, or guess) into the green - shaded areas, and it automatically calculates all of the income generated in all of the different time frames (along with all of the totals).

At times these divers disagree with me, and I certainly appreciate hearing the different point - of - views these fellow enthusiasts have — even when I think they are wrong!

What this means is that anyone can get these points when the time comes by opening a few different credit cards with good signup bonuses and the points will all transfer over — as long as it's one of the transferable currencies I mentioned.

If you prefer gift cards, you will have a lot of different gift cards to choose from when it comes time to redeem your points.

- for Sonic's 25th anniversary last year, Iizuka received a task to deliver some sort of product - the target was «dormant fans» who used to play the SEGA Genesis, but haven't really played any games since - Iizuka met Christian Whitehead, which lead to the creation of Sonic Mania - there was talk of another port, but Iizuka thought fans would desire something new from the old games - this is the first time Iizuka partnered with a team of devs spread across various countries - Iizuka said this team had a greater passion to create - this was in comparison to companies that set decisions on a pre-determined schedule (in meetings, etc)- the team had so many features they still wanted to add after the beta version was complete - since there were only a few spots with text that needed to be localized, they could bring the game to more places quicker - the game has Japanese, English, French, Italian, German, and Spanish support - the Studiopolis stage is included due to receiving the most requests from the Sonic Mania development team - Iizuka actually considered reducing the amount of stages at one point in order to meet the development schedule - Sonic Mania doesn't really have much in the way of cut content like scrapped stages - since Sonic Mania was only distributed digitally, the team was able to continue working very close leading up to launch - this let them put in practically all ideas, and there are currently no plans for DLC - Iizuka recommended Flying Battery Zone for inclusion becaues he likes the music - he also likes when the player goes inside and outside the ship - Iizuka likes Mirage Saloon because the stage structure will be different depending on the player character chosen - Puyo Puyo gameplay was added because there was a Puyo Puyo game released in the west for the SEGA Genesis - this game was originally called «Dr. Robotnik's Mean Bean Machine», and the team thought it would make a fun boss battle - Iizuka didn't have plans to feature Blue Sphere in the special stages - the Blue Sphere special stages were brought over to Mania as a test, but ended up staying for the final game - the team felt the need to continuously connect stages from various eras, which is doe with the Phantom Ruby story - for Sonic Mania, it was decided that the technological limit would be set at SEGA CD, - this is higher than the Genesis but lower than Saturn - in creating a SEGA CD - grade special stage, they would intentionally make SEGA CD - grade polygons

- the team has been adding weapons one by one because they want the same amount of attention for each weapon - the team learned that when they added two new weapons at once, one would end up getting overshadowed by the other - there were more new stages than returning stages because bringing back old stages would have little surprise - since they want to satisfy both new and returning players, they changed the order of stage additions - there weren't any major direction changes in balancing from Splatoon 1 - there have been more pattern combinations between weapons and stages, so there was more involved to balance them all - matchmaking is handled by getting 8 players with similar rank points, and then they're split by weapons - the rank point gap between S + players is bigger than ordinary players - only about one in 1,000 active players are in the S +40 to S +50 region in Ranked Battles - there's even less than one in 10 players that reach S +, while 80 % of the overall player base are in A or less - about 90 % of S + ranked players are within a + / -150 hidden ranked power range - rock was the popular genre in Splatoon, so they tried changing it for the sequel - they prioritized making good background music first before forming the band to play that music - the design team would make the CD jacket - like artwork afterwards - due to this, the band members would often change; some getting added while some others removed - Off the Hook is an exception, as they first decided they would be a DJ and rapper along with their visuals first - Off the Hook's song came afterwards - In Splatoon street fashion was the trend, but in Splatoon 2 they tried adding more uniqueness - the aim was to add Flow with ethnic clothing and Jelfonzo with high fashion - all Jellyfish in this world are born by splitting, which means Jelfonzo was born by splitting from Jelonzo - Jellyfish are like a hive mind - when they hold a wedding ceremony, they're just simply holding the ceremony - Jelonzo and Jelfonzo start gaining their own consciences so they can speak - Flow used her working holiday to go on a trip before reaching Inkopolis Square - during the trip, she met the owner of Headspace - the owner liked her, so she got hired to work there - Bisk has a unique way of speaking: anastrophe - the team tried to express him as an adult man - they made him into a giant spider crab because they wanted someone with high posture - he came from a cold country and broke up with his girlfriend to join a band - just like Flow, he became attracted to squids - Crusty Sean finally has his own shop, but he opened it because he's someone who follows the current trends - one of the trends happens to be people opening their own shops - drink tickets aren't stacked, but the probability is higher than a single brand - the music in Inkopolis Square changes depending on the player's location - sounds contribute to creating atmosphere in the location - the song at front of Grizzco Industries had an atmosphere that feels like some smell can radiate from the game screen - as for Salmon Run, they imagined it as a Japanese restaurant outside Japan that is not run by a Japanese person - each time the player moves between the shops, the game uses an arrange shift that shows the personality of each inhabitant - the arrangement in Shella Fresh is related to Bisk's guitar and mystery files that describe his past - with the Squid Sisters moved to Hero Mode, Off the Hook was put in charge in guiding battles and festivals - Bomb Rush Blush has an orchestra «because it would sound like the final boss» - the team wanted to express the feel of the story's real culprit with this music - the probability of each event occurring in Salmon Run is different - there are no specific requirements, meaning they're picked randomly - this means it's possible for fog to appear three times in a row - the Salmon have different appearances based on the environment they're raised in - if the environment is harsher, they would become large salmon - Steelheads and Maws have big bodies, while Scrappers and Steel Eels have high intelligence - Salmons basically wield kitchenware, but everybody else has a virtue in fighting to actually cook the Salmons - Grill is the ultimate form of this - when Salmons are fighting to the death, they can feel the same sense of unity - they would be one with the world if they were eaten by other creatures, and they also fight for the pride of their race - MakoMart is based on a large supermarket in America - the update also took place on Black Friday in America, which was why Squids are buying a lot of things in the trailer - Arowana Mall looks like it has more passages because there are changes in tenants and also renovation work - Walleye Warehouse has no changes at all, because the team wanted to have at least one map that stayed intact - the only thing different in this map is the graffiti, which is based on the winner of Famitsu's Squid Fashion Contest - all members in the band Ink Theory graduated from music university - they are well - educated girls who also do aggressive things - the band members wearing neckties are respecting the Hightide Era from the prequel - the team will continue adding weapons and stages for a year, and Splatfests for two years - the team will also continue to make more updates including balancing

-- Nintendo previously made Zelda games by making small areas and connecting them together — For Breath of the Wild, the team first had to figure out what needed to be placed on the map — Groups were created out of the over 300 devs to work on specific sections of the world — Game Informer's demo starts at Serenne Stable — Yammo runs this place — Link can rest in bed and restore health here — Stable also lets you store horses, meet with merchants, NPCs — Stables are located throughout the world — Each one is run by a distinct character — You can spend rupees on a more expensive bed, giving you an extra heart the next morning — These hearts are yellow and can't be recovered if you're hit in combat — Spending time by fires in the world passes time — Dynamic weather system in the game, with the world reacting as a result — Ex: when it starts raining, NPCs outside the stable quickly go inside — Beedle is back to sell you goods — Have to be careful during a thunderstorm, since your metal items can attract thunder — Metal weapons and shields can be discarded or thrown at enemies — Link can get killed by lightning — Difficulty dips / spikes depending on where you are, since you can go around it and avoid it until you're stronger — Over 100 Shrines — You can find an item that identifies Shrines — Discover a Shrine for it to be a fast - travel point — Shrines also give a Spirit Orb — Trade in orbs for unknown items — Dedicated team handled animal A.I. — Bears, wolves, deer move through the snow — You can get overwhelmed by enemies quickly — Link can keep multiple horses at a time — Affection / loyalty important with horses — Feed and take care of horses to raise their stats — Can call horses over to you, but horses need to be within a certain proximity to be called — Horses can be killed by enemies — Aonuma «wanted players to choose their own path», so no companion character in this game — Stamina meter encopasses sprinting, paragliding, climbing — Meter can be upgraded, but Nintendo won't say how — Different shields have different speeds and level of control for snowboarding — Can mine rocks which can be solid for rupees or used for crafting — Can place stamps to mark areas of interest — 100 of these symbols can be used on the map, including sword, shield, bow and arrow, pot, star, chest, skull, leaf, diamond — Every style of weapon has a unique set of animations and feel different — No invincible weapons in the game, Nintendo says — Zelda can get mad at you and scold you — Players can see the ending without seeing everything from the story — A certain element was added in the game to make for a more cohesive storyline — Most difficult Zelda game to make — Aonuma is still finding new things in Different shields have different speeds and level of control for snowboarding — Can mine rocks which can be solid for rupees or used for crafting — Can place stamps to mark areas of interest — 100 of these symbols can be used on the map, including sword, shield, bow and arrow, pot, star, chest, skull, leaf, diamond — Every style of weapon has a unique set of animations and feel different — No invincible weapons in the game, Nintendo says — Zelda can get mad at you and scold you — Players can see the ending without seeing everything from the story — A certain element was added in the game to make for a more cohesive storyline — Most difficult Zelda game to make — Aonuma is still finding new things in different speeds and level of control for snowboarding — Can mine rocks which can be solid for rupees or used for crafting — Can place stamps to mark areas of interest — 100 of these symbols can be used on the map, including sword, shield, bow and arrow, pot, star, chest, skull, leaf, diamond — Every style of weapon has a unique set of animations and feel different — No invincible weapons in the game, Nintendo says — Zelda can get mad at you and scold you — Players can see the ending without seeing everything from the story — A certain element was added in the game to make for a more cohesive storyline — Most difficult Zelda game to make — Aonuma is still finding new things in different — No invincible weapons in the game, Nintendo says — Zelda can get mad at you and scold you — Players can see the ending without seeing everything from the story — A certain element was added in the game to make for a more cohesive storyline — Most difficult Zelda game to make — Aonuma is still finding new things in the world

On some levels, I had a difficult time beating the AI when I approached the level in a straightforward do - as - expected gameplay... but when I realized that I could instead «cheese» my opponent by simply spamming my swarming units early in the game, forcing the AI to overcompensate by building only towers effective against that unit type, at which point I could finish them off by suddenly switching to a different unit.

Although each series emerged at different times during the artist's career, he now often works simultaneously on all three in an organic manner, as he points out: «when I was working on Terrazzo, Coffin Paint, and Untitled, I didn't distinguish much between them, though they developed a complementary relationship as I worked.»

Now, when the slope of a linear regression changes drastically when you choose different end points of (say) 11, 10, 9, or 8 years, this tells you something important about the underlying time series.

Many things are different when Millennials are in the parenting seat, as the Times points out.

When I pointed out that I had revised my e-mail contact info some time ago and received many e-mails from the company at my correct address, he explained that cancellation notices were sent from a different server that had never been updated with my correct information.

Nicole Hyland: This is one time when I did because I originally did my analysis under the New York rules and someone pointed out that it might be different under New Mexico so I did take that extra step at that point to go and research New Mexico.

This grabs people through very specific location analysis and a bunch of different data points, to connect certain messages to real people at the right place and the right time, and probably when certain types of people are together.

• Eye of Obsidian adds a brand new chapter in the ReCore story • T8 - NK Corebot • 2 New Overworlds • 10 New Dungeons • Dynamic sandstorms in Shifting Sands • 3 new weapon modes for Joule's Energy Rifle • When dying reload times for combat encounters went from 30 - 60 seconds to < 5 seconds • Restarting traversals and arenas are now instantaneous • Added P - Cores for additional game play rewards • P - Core requirements fixed to a single value for the entire E-Tower • The Map displays everything that needs to be collected (audio logs, chests, prismatic cores) • The Map shows all visual parts of dungeon maps • Objective Markers improved • Fast Travel points now allow the player to complete Stash Transfers, Swap Cores and set Companion Party Configuration without having to go back to the Sandcrawler • The player can now warp anywhere there is a Fast Travel node via the Map • Intra-Level (e.g. within The Cradle) fast travel warping is now instantaneous • Added new Fast Travel nodes (Granite Steps, Lonely Basin, The Cradle) • New AoK gear for all Corebots • Armor stats now make each set vastly different from one another • Blueprint Inventory now sorts by Armor Type, Color and LVL requirement • Improved the Combo Meter • Enhanced visuals (increased resolution and HDR) • 20 New Achievements • Increased level cap from 30 to 40 • 4 new bosses and Tank challenges • Dialogue from Corebots and Violet is no longer in the Corebot language and is now readable

There are now three different ways to scramble over cover: by point the control stick forward and tapping «A» when you're already in cover, by holding «A» and «B» (which is just the worst) simultaneously as you run toward cover, or by tapping «A» to slide toward cover, then quickly tapping «B,» the timing of which is extremely tricky.

I can say that even though I may have started in REI when I was much younger, I could also say that I've restarted a number of times based on using a number of different starting points.