Sentences with phrase «different tumour types»

The next step is to try and understand how these seemingly very different tumour types are able to adapt their energy production to grow.

By comparing the conversations, the researchers made the surprising discovery that similar reactions were taking place in different tumour types.

Not exact matches

Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.

The researchers found five different sub-types of HL among the patients studied: 247 cases of the nodular sclerosis (NS) type, in which the tumour nodules are large; 105 of mixed cellularity, where a mixture of different types of inflammatory cells are involved; 58 lymphocyte rich, the sub-type with the best outcome; 68 «others»; and 143 «not otherwise specified» (NOS).

The team used five types of antibiotics — including one used to treat acne (doxycycline)-- on cell lines of eight different types of tumour and found that four of them eradicated the cancer stem cells in every test.

The use of whole genome sequencing enables researchers to accurately distinguish between tumour types with different treatment strategies.

The CNIO researchers show that cell defects caused by the inhibition of Cdh1 are independent of the presence of the p53 molecule, which is mutated in different types of tumours.

While it is present on a number of different types of cells in the body, it is expressed at higher levels on metastatic tumour cells, including those which have spread from the lung.

Although most of the work has been carried out using in vivo studies, Asst Prof Gasser has been collaborating with Dr Joanne Ngeow at the National Cancer Centre Singapore to characterise the process in different types of human tumours.

They analysed about a million different cell mutations in more than 7,000 tumours from the Cancer Genome Atlas covering 24 types of cancer.

We see extensive variability in genomes among tumours of different tissue types, among different patients within a tissue type and among subclones within a given patient's cancer.

Although these processes are affected by many different cell types within the tumour stroma, macrophages and other myeloid - derived cells are among the most important players.

Professor John Griffiths, co-lead researcher based at the Cancer Research UK Cambridge Institute, said: «The revelation that different types of brain tumours appear to be using similar tricks to survive was startling.

TCGA has generated vast amounts of data through the analysis of primary tumours from 33 different types of cancer, collecting 7 different data types.

The program works by looking for specific molecular patterns in cancer DNA that is free flowing in the patients» blood and comparing the patterns against a database of tumour epigenetics, from different cancer types, collated by the authors.

The results suggest that brain tumours adapt their chemical reactions in very similar ways to survive in the brain, despite starting in very different types of cells and regions.

Different types of brain tumours may use strikingly similar approaches to generate and use energy to survive in the brain, according to a new study * published in PLOS ONE.

While there are many different types of cancer, all of them stem from the abnormal growth of cells that invade numerous body sites, quickly leading to the formation of tumours that are either benign (restricted to a local area and removable) or malignant (invasive, spreading throughout the body).