Sentences with phrase «different types of cells using»

«Our group pioneered the development of cell culture technology for harvesting large numbers of stem cells from human bone marrow and human umbilical cord blood,» Dr. Yeh said, noting that stem cells from these two sources are abundant and can be guided into different types of cells using tissue engineering.

Not exact matches

Monica knew from the start that he wanted to use a different type of foam than the black, open - celled polyurethane that is standard among competitor models.

«What this research shows is that they're using the same cell types with the same kinds of connections we see in the neocortex, but with a very different kind of organization.»

In the journal Biomaterials, the team reports culturing cells to make extracellular matrix (ECM) of two types and five different alignments with the strength found in natural tissue and without using any artificial chemicals that could make it incompatible to implant.

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

In order to isolate the 3D structure of the chromosome during metaphase, the authors used a combination of chromosome conformation capture technologies (3C, 5C and Hi - C) developed by the Dekker lab over the last decade to map the points of contact along the mitotic chromosome in different cell types synchronized to divide at the same time.

Using tumor samples from a patient, they do lab tests to determine which substances can first make the different types of cancer cells uniform and then effectively kill them.

Cellular toxicity was unrelated to the type of «carrier» solution used in the cell cultures, the use of HES made from different origins (potato versus corn starch), or the time cells spent in culture with HES.

Human epidermal equivalents representing different types of skin could also be grown, depending on the source of the stem cells used, and could thus be tailored to study a range of skin conditions and sensitivities in different populations.»

Backman has been studying cell abnormalities at the nanoscale in many different types of cancers, using an optical technique he pioneered called partial wave spectroscopic (PWS) microscopy.

«When you look at the varying types of cell morphologies that correspond to different leukemias, you can statistically look at enough cells using this system to be able to classify different kinds of leukemias,» says Yousaf.

The team used five types of antibiotics — including one used to treat acne (doxycycline)-- on cell lines of eight different types of tumour and found that four of them eradicated the cancer stem cells in every test.

Using DNA strands just 58 nucleotides long to uniquely identify each particle allows researchers to skip the cell culture screening altogether — and test a hundred or more different types of nanoparticles simultaneously in just a handful of animals.

In a Developmental Cell paper publishing October 13, researchers demonstrate that the single - celled ancestor of animals likely already had some of the mechanisms that animal cells use today to develop into different tissue types.

To make the pigmented skin constructs, the team used three different types of skin cells — keratinocytes, melanocytes, and fibroblasts — and a two - step «drop on demand» bioprinting method.

«Although right now we are focusing on developing a cancer vaccine, in the future we could be able to manipulate which type of dendritic cells or other types of immune cells are recruited to the 3D scaffold by using different kinds of cytokines released from the MSRs,» said co-lead author Aileen Li, a graduate student pursuing her Ph.D. in bioengineering at Harvard SEAS.

Depositing the cells with the micro-fabricated, funnel - like insert allows the insert to be used with any type of chip platform or cell type, because it doesn't require patterning the chip's surface with different chemicals to adhere the cells to it.

Such measurements could be used to sort different types of cells — to distinguish cancerous cells from healthy ones, for example — or to measure how cells change when exposed to drugs.

It has billions of parts, many used to activate and silence genes — an arrangement that allows individual cells to specialize as brain cells, heart cells and some 200 other different cell types.

The next steps for Zhang and his team is to focus mostly on using the agent on different types of stem cells and to test them in vivo.

They used genetic knockout mice to look for the cells, silencing different types of TRCs, then flushing the rodents» mouths with water to see which cells responded.

The follow up Biosensors paper, provides a proof - of - principle use of these probes as tools to assess and compare GLUT5 and metabolic activity of different cell types, including normal cells and different cancer subtypes.

Christian Seiser says: «Our results highlight that it is crucial to understand the individual role the various HDAC variants in different cell types and hence different types of cancer, before HDAC inhibitors can be used safely as therapeutics.»

Using different types of perovskites across multiple layers could allow solar cells to more effectively absorb a broader range of photons.

Using tissue culture models of cartilage and the meniscus, Levenston's team stresses the cells and tissues and studies what happens to them structurally and biochemically — for example, whether different genes are expressed, whether metabolism changes, or whether different types of cartilage cells respond differently to the same stress.

Cells may use different rates of translation in different types of mRNA to produce the right amounts and ratios of required proteins.

By seeding elements with an assortment of antibodies, the device could be set up to capture several different cancer cells types using a single blood sample.

Because stem cells have the ability to develop into many different cell types in the body, researchers at USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery & Brain Repair have focused on using stem cells to restore function lost through neurodegenerative disorders or injuries.

So to be able to make the most efficient use of the sunlight, one of the possibilities is to build tandem - type structures, in other words, to fit the cells manufactured with different polymers one on top of the other,» explained Etxebarria.

Earlier this year, scientists at University of California, Los Angeles, and Advanced Cell Technology of Marlborough, Massachusetts, reported in The Lancet about the safe and successful use of RPE cells derived from human embryonic stem cells, rather than iPS cells, to treat a different type of AMD in a limited number of human patients.

Using the spinal cord as a model, Jessell deciphered at the molecular level how different types of nerve cells are generated as well as the steps that drive their assembly into the circuits mediating motor coordination and reflexive behaviours.

«We thought, why not use a different cell type — and we can easily get access to fat,» says Joseph Wu, a co-author of a study on this process and assistant professor of medicine at Stanford.

During the 20th century molecular techniques have enabled researchers to investigate how different genes and proteins are used in different parts of tissues, to understand how cell types collaborate in tissues.

Using machine learning technology, the researchers analyzed hundreds of existing datasets from six different cell types to look for patterns in the genome that identify where a gene and enhancer interact.

A research team, led by Chao Cheng, Ph.D., Assistant Professor in the Department of Genetics at The Geisel School of Medicine at Dartmouth, used gene expression data from breast cancer patients to computationally infer the presence of different types of immune cells.

Genome editing is used in many different cell types and organisms to specifically modify genes for the interrogation of fundamental cellular pathways.

Humans have many cell types - nerve cells, blood cells, skin cells, to name a few - and while each cell contains the same genetic instructions, different parts of the genetic information are used to produce proteins in each type of cell.

For instance, the trials underway in China and Australia use neural progenitor cells that can grow to become a variety of different cell types.

I and a colleague have attempted to use this on two different types of cell lines using Flow cytometry and fluorescence microscopy all of which proved unsuccessful.

Working in mice, Norbury's team used several methods to deplete different types of innate immune cells — collectively known as myeloid cells — at the three checkpoints before infecting the rodents with poxvirus.

Among the strengths of the study: instead of using just one method to deplete macrophages, the researchers used nine distinct methods to deplete different myeloid cells in various locations, allowing them to pinpoint the most important cell type and its primary location of action.

Mechanical properties of many different cell types including glial cells, platelets, cardiocytes, macrophages, endothelial cells, epithelial cells, fibroblasts, bladder cells and more have been determined using F - d spectroscopy.

«We compiled a list of the proteins we thought Zika and similar viruses like dengue were using to get inside of cells, and then we looked to see which of these proteins were abundantly present in the different cell types of the developing brain,» said Pollen, who did the work with Tomasz Nowakowski, PhD, and a UCSF graduate student Carmen Sandoval - Espinosa, BS, both in Kriegstein's lab.

Even though different cell types were used as the initial starting materials, and they were made to produce different sets of proteins, both groups identified and isolated cells nearly identical to human embryonic stem cells, and did so in the same timeframe.

The current study involved monitoring the patients for one year after completed stem cell transplantation and used mass cytometry to study the different cell types of the immune system and the so called ProSeek method for simultaneous protein analysis.

Yet this study brings us tantalisingly close to using skin cells to grow many different types of human tissues.

Using the spinal cord as a model, Jessell deciphered at the molecular level how different types of nerve cells are generated, as well as the steps that drive their assembly into the circuits mediating motor coordination and reflexive behaviors.

Even though different cell types were used as the initial starting materials, and they were made to produce different sets of proteins, both groups were able to identify and isolate hESC - like cell colonies only 20 to 30 days after transduction.

Teitell used embryonic stem cell lines that made different types of neurons and studied them with array CGH for comparison.

«The best case scenario is that from this one very accessible and highly proliferative source of stem cells, we will be able to obtain multiple different cell types that can be used for a broad range of applications in regenerative medicine,» he said.