Canine research has allowed researchers to identify genes linked to
different types of lymphoma in dogs that are also linked with lymphoma in humans.
Combined data from
different types of lymphoma demonstrated 44 % of overall survival and 39 % of complete remission.
BI-1206 showed remarkable success in mice in overcoming resistance to monoclonal antibodies like rituximab, currently used to treat
different types of lymphoma and leukemia.
The different types of lymphoma span from the aggressive to those that have a relatively mild outcome.
Not exact matches
This work was carried out with funding from the Association for International Cancer Research (United Kingdom), the
Lymphoma Research Foundation (USA) and the Instituto de Salud Carlos III (Spain), and illustrates how new genome sequencing technologies are revolutionizing the study
of different types of cancer.
In a study
of 30 patients who received CTL019 for three
different types of non-Hodgkin
lymphoma, the researchers found that 59 percent
of patients responded to the therapy (17
of 29, 15
of who experienced complete remissions
of their disease).
The treatment methods for these two
types of lymphomas are very
different.
Non-Hodgkin
lymphoma — sometimes also called non-Hodgkin's
lymphoma or just NHL — covers a number
of different cancers that start in a specific
type of white blood cells called lymphocytes.
Unlike NHL, which has many
different subtypes, Hodgkin
lymphoma is mostly distinguished by the presence
of what's called Reed - Sternberg cells, or abnormal
types of a specific lymphocyte.
Cell - based vaccine strategies that stimulate anti-tumor immunity have shown promise in the treatment
of many
different cancer
types including non-Hodgkin's
lymphoma (NHL) in humans.