Different types of tumors show a preference for specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.
«Our work outlines the genetic similarities of the tissue and cells
in different types of tumors and shows the strong relationships mice can have to other human cancers too.»
-- discovery awarded international science prize Researcher Allison Cleary has, for the first time, demonstrated that
different types of tumor cells cooperate in the development and growth of breast cancer.
Their strategy, described in the Jan. 4, 2009 issue of the journal Nature Medicine, could not only prove a very useful method to faithfully
reproduce different types of tumors but also to elucidate the nature of elusive cancer stem cells.
The researchers also note that more investigation is needed to fully understand all the mechanisms by which HOXC10 mediates cell proliferation and death, and the roles it may play
in different types of tumors.
Researcher Allison Cleary has, for the first time, demonstrated that
different types of tumor cells cooperate in the development and growth of breast cancer.
The researchers tested this combination treatment in mice that were implanted with three
different types of tumors — melanoma, lymphoma, and breast cancer.
The circuit, which can be customized to respond to
different types of tumor, is based on the simple AND gates used in electronics.
«If we can understand the genetic events causing the development of
these different types of tumors, we can point away from certain types of treatments and refine the therapies we recommend,» said Mark Applebaum, MD, assistant professor of pediatrics at the University of Chicago Medicine.
Now we want to extend this technology to animal models, such as cancer bearing mice, to verify its practical use in
different types of tumors,» explains Park.
Different types of tumors are formed by specific kinds of microbes.